Neuroendoscopy in the management of pineal tumors

Tai-Tong Wong, Hsin Hung Chen, Muh Lii Liang, Yu Shu Yen, Feng Chi Chang

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Introduction: Endoscopy has been applied for the management of pineal tumors and the associated obstructive hydrocephalus. The techniques include endoscopic third ventriculostomy (ETV), endoscopic biopsy, and endoscopicassisted open surgery of tumor in selected cases. The purpose of this study is to report our experience and techniques of endoscopic surgeries for pineal tumors in children. Methods: This is a retrospective review of 36 ETVs, 25 endoscopic transventricular biopsies (ETB), 2 endoscopic transnasal transsphenoid biopsies, and 5 endoscopic-assisted open resections of pineal tumors. Results: One patient died of delay tumor hemorrhage after ETV and ETB were excluded. With a mean follow-up period of 5.4 years, ETV failure occurred in 7 of 35 patients with long-term success rate of 80.0%. Histological diagnosis was established in 21 of 25 (84.0%) patients through ETBs. Tissue diagnosis was obtained in two selected patients with bifocal germ cell tumors by endsocopic transnasal transsphenoid approach to the intrasellar lesion. Direct radical resections were achieved in four of five selected patients of pineal tumors with hydrocephalus by endoscopic-assisted open surgery.

Original languageEnglish
Pages (from-to)949-959
Number of pages11
JournalChild's Nervous System
Volume27
Issue number6
DOIs
Publication statusPublished - Jun 1 2011
Externally publishedYes

Keywords

  • Endoscopic third ventriculostomy
  • Endoscopic transnasal transsphenoidal approach
  • Endoscopic transventricular biopsy
  • Endoscopic-assisted open surgery
  • Neuroendoscopy
  • Pineal tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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  • Cite this

    Wong, T-T., Chen, H. H., Liang, M. L., Yen, Y. S., & Chang, F. C. (2011). Neuroendoscopy in the management of pineal tumors. Child's Nervous System, 27(6), 949-959. https://doi.org/10.1007/s00381-010-1325-5