Neuroendoscopic techniques in the management of pineal region tumors

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In recent years, the use of the endoscope is a valid alternative to the classical microscopical approaches for the treatment of the pineal tumors. It can be used for endoscopic tumor biopsy (ETB) as well as endoscopic-assisted complete tumor removal in some cases. At the same time, if there is coexisting hydrocephalus, this can be treated endoscopically with endoscopic third ventriculostomy (ETV). The management of pineal region tumors can be summarized as follows: 1. In case of suspected germinoma or pineoblastoma with accompanying hydrocephalus and normal values of AFP and β-hCG, we propose endoscopic tumor biopsy and third ventriculostomy. If the biopsy provides tumor-type diagnosis, further oncological management is pursued as the next step. 2. In case of suspected mature teratoma, non-germinomatous malignant germ cell tumor (NGMGCT), or other tumors, we propose radical excision of the tumor, endoscopically assisted when needed and navigation assisted if necessary. 3. In case of midbrain tumors, we propose endoscopic third ventriculostomy combined with biopsy in selected cases. In some cases an endoscopic removal of the tumor can be achieved. Endoscopic third ventriculostomy has a high success rate in dealing with the hydrocephalus caused by pineal region tumors. At the same time, biopsy samples can be obtained with the endoscope from tumors which protrude in the third ventricle, with good yield rate, comparable to stereotactic biopsy. In selected cases, endoscopy-assisted surgical techniques can be employed to remove pineal region tumors. Complication rate for these procedures is low.

Original languageEnglish
Title of host publicationNeuroendoscopy
Subtitle of host publicationCurrent Status and Future Trends
PublisherSpringer Berlin Heidelberg
Pages161-173
Number of pages13
ISBN (Electronic)9783642390852
ISBN (Print)9783642390845
DOIs
Publication statusPublished - Jan 1 2014
Externally publishedYes

Fingerprint

Pinealoma
Ventriculostomy
Biopsy
Neoplasms
Hydrocephalus
Endoscopes
Brain Stem Neoplasms
Germinoma
Third Ventricle
Germ Cell and Embryonal Neoplasms
Teratoma
Endoscopy
Reference Values

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Wong, T-T. (2014). Neuroendoscopic techniques in the management of pineal region tumors. In Neuroendoscopy: Current Status and Future Trends (pp. 161-173). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-39085-2_14

Neuroendoscopic techniques in the management of pineal region tumors. / Wong, Tai-Tong.

Neuroendoscopy: Current Status and Future Trends. Springer Berlin Heidelberg, 2014. p. 161-173.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wong, T-T 2014, Neuroendoscopic techniques in the management of pineal region tumors. in Neuroendoscopy: Current Status and Future Trends. Springer Berlin Heidelberg, pp. 161-173. https://doi.org/10.1007/978-3-642-39085-2_14
Wong T-T. Neuroendoscopic techniques in the management of pineal region tumors. In Neuroendoscopy: Current Status and Future Trends. Springer Berlin Heidelberg. 2014. p. 161-173 https://doi.org/10.1007/978-3-642-39085-2_14
Wong, Tai-Tong. / Neuroendoscopic techniques in the management of pineal region tumors. Neuroendoscopy: Current Status and Future Trends. Springer Berlin Heidelberg, 2014. pp. 161-173
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