Neurocognitive attention and behavior outcome of school-age children with a history of febrile convulsions: A population study

Ying Chao Chang, Nai Wen Guo, Chao Ching Huang, Shan Tair Wang, Jing Jane Tsai

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Purpose: A prospective population-based case-control study was performed to ascertain whether febrile convulsion (FC) in early childhood is associated with neurocognitive attention deficits in school age. Methods: A total of 103 children, confirmed to have FC by age 3 years from a population survey of 4,340 live-birth newborns in Tainan City, Taiwan, was followed up until at least age 6 years. An achievement test, behavioral ratings, and computerized neurocognitive battery assessing various subcomponents of attention were given to 87 FC children (FC group) and 87 randomly selected population- matched control (CC group). Results: Compared with the CC group, the FC group did not have scholastic performance or behavioral outcome disadvantage. Overall FC group performance was distinguished by significantly higher scores in the achievement test and fewer missing errors (p <0.005) and commission errors (p <0.05), less variability in reaction time (p <0.005), and a nonsignificant trend of impulsivity. Attention performance of the FC and CC groups were comparable. Within the FC group, age at onset, complex FC, recurrence of FC, development of unprovoked seizures, or prior use of phenobarbital had no adverse effects on neurocognitive attention outcome. Conclusions: This population study suggests that FC in early childhood does not have adverse effects on behavior, scholastic performance, and neurocognitive attention. On the contrary, the FC group demonstrated significantly better control of distractibility and attention at school age.

Original languageEnglish
Pages (from-to)412-420
Number of pages9
JournalEpilepsia
Volume41
Issue number4
Publication statusPublished - 2000
Externally publishedYes

Fingerprint

Febrile Seizures
Population
Population Control
Impulsive Behavior
Live Birth
Phenobarbital
Taiwan
Age of Onset
Reaction Time
Case-Control Studies
Seizures

Keywords

  • Attention
  • Febrile convulsion
  • Neurocognition
  • Outcome

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Neurocognitive attention and behavior outcome of school-age children with a history of febrile convulsions : A population study. / Chang, Ying Chao; Guo, Nai Wen; Huang, Chao Ching; Wang, Shan Tair; Tsai, Jing Jane.

In: Epilepsia, Vol. 41, No. 4, 2000, p. 412-420.

Research output: Contribution to journalArticle

Chang, Ying Chao ; Guo, Nai Wen ; Huang, Chao Ching ; Wang, Shan Tair ; Tsai, Jing Jane. / Neurocognitive attention and behavior outcome of school-age children with a history of febrile convulsions : A population study. In: Epilepsia. 2000 ; Vol. 41, No. 4. pp. 412-420.
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