Neonatal outcomes in relation to sex differences: A national cohort survey in Taiwan

Yi Hao Weng, Chun Yuh Yang, Ya Wen Chiu

Research output: Contribution to journalArticle

11 Citations (Scopus)


Background: An extensive assessment investigating the association between sex differences and neonatal outcomes is lacking. In the current study, we estimated the correlation of gender with adverse birth outcomes in a large cohort population. Methods: National population-based data containing maternal and neonatal information in 2001 to 2010 were derived from the Health Promotion Administration, Taiwan. Singletons without high-risk pregnancy were further analyzed for the sex ratio of live births in relation to neonatal outcomes-including preterm birth, birth weight, neonatal death, delivery mode, and congenital anomaly. A multivariate logistic regression model was used to adjust for possible confounders. Results: In total, 2,123,100 births were valid for the analysis. Overall, the sex ratio at birth (male/female) was 1.096. Compared to multiple births, the sex ratio was significantly higher with singleton births (p <0.001). Among multiple births, the incidence of stillbirths was significantly higher in males than in females (p <0.05). The sex ratio at gestational age (GA)

Original languageEnglish
JournalBiology of Sex Differences
Publication statusAccepted/In press - Dec 9 2015


  • Birth outcome
  • Birth weight
  • Cesarean section
  • Congenital anomaly
  • Gender
  • Gestational age
  • Sex ratio

ASJC Scopus subject areas

  • Endocrinology
  • Gender Studies

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