Necrotising pneumonitis in children

Kin Sun Wong, Cheng Hsun Chiu, Kee Min Yeow, Yhu Chering Huang, Hui Ping Liu, Tzou Yien Lin

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

We retrospectively analysed the clinical features and outcome of children under 17 years of age with necrotising pneumonitis (NP). The radiographs and CT scans of the chest of children under 17 years of age between July 1995 and March 1999 who had complicating community-acquired pneumonia were reviewed. CT scans were obtained for persistent fever, respiratory distress and sepsis despite empiric antibiotic therapy and closed tube drainage. A total of 21 children had the radiographic features of NP of whom 11 (52%) patients were successfully managed using antibiotic therapy with or without closed tube drainage. Ten patients required thoracoscopic decortications and/or lysis of pleural adhesions or debridement of empyema due to refractory pleural sepsis, failure of pulmonary re-expansion and persistent air-leaks. The most common pathogens identified were Streptococcus pneumoniae (n = 3), Staphylococcus aureus (n = 2), and Haemophilus infiuenzae type b (n = 2). The days of hospital stay, duration of fever and days of C-reactive protein return to normal were significantly less for the medically versus the surgically treated children (P < 0.05). Conclusion: The clinical course of necrotising pneumonitis in children following complicated pneumonia is often prolonged despite adequate antibiotic therapy. Necrotising pneumonitis with co-existing multiple loculations, pneumothorax/bronchopleural fistula in the empyema and extensive pleural peel are poor prognostic factors for medical therapy. Thoracoscopic removal of loculated empyema lysis of adhesions and/or decortication are effective in relieving tachypnoea, chest pain, and controlling fever and improve the outcome, especially in children with empyema.

Original languageEnglish
Pages (from-to)684-688
Number of pages5
JournalEuropean Journal of Pediatrics
Volume159
Issue number9
Publication statusPublished - 2000
Externally publishedYes

Fingerprint

Pneumonia
Empyema
Fever
Anti-Bacterial Agents
Drainage
Sepsis
Pleural Empyema
Haemophilus
Tachypnea
Pneumothorax
Debridement
Therapeutics
Streptococcus pneumoniae
Chest Pain
C-Reactive Protein
Fistula
Staphylococcus aureus
Length of Stay
Thorax
Air

Keywords

  • Childhood necrotising pneumonitis
  • Empyema
  • Video-assisted thoracoscopic surgery

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Wong, K. S., Chiu, C. H., Yeow, K. M., Huang, Y. C., Liu, H. P., & Lin, T. Y. (2000). Necrotising pneumonitis in children. European Journal of Pediatrics, 159(9), 684-688.

Necrotising pneumonitis in children. / Wong, Kin Sun; Chiu, Cheng Hsun; Yeow, Kee Min; Huang, Yhu Chering; Liu, Hui Ping; Lin, Tzou Yien.

In: European Journal of Pediatrics, Vol. 159, No. 9, 2000, p. 684-688.

Research output: Contribution to journalArticle

Wong, KS, Chiu, CH, Yeow, KM, Huang, YC, Liu, HP & Lin, TY 2000, 'Necrotising pneumonitis in children', European Journal of Pediatrics, vol. 159, no. 9, pp. 684-688.
Wong KS, Chiu CH, Yeow KM, Huang YC, Liu HP, Lin TY. Necrotising pneumonitis in children. European Journal of Pediatrics. 2000;159(9):684-688.
Wong, Kin Sun ; Chiu, Cheng Hsun ; Yeow, Kee Min ; Huang, Yhu Chering ; Liu, Hui Ping ; Lin, Tzou Yien. / Necrotising pneumonitis in children. In: European Journal of Pediatrics. 2000 ; Vol. 159, No. 9. pp. 684-688.
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