Nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study: Design and methods

on behalf of the Taiwan Consortium for Acute Kidney Injury Renal Diseases (CAKs)

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Aim: Acute kidney injury (AKI) carries an increasing incidence rate worldwide and increases the risk of developing end-stage renal disease (ESRD) as well as the medical expenses during the post-AKI course. The Taiwan Consortium for Acute Kidney Injury and Renal Diseases (CAKs) has thus launched a nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study, which prospectively enrols critically ill patients with AKI. Through thoroughly evaluating the risk and prognostic factors of AKI, we hope to lower the incidence of AKI and ESRD from the perspective of AKI-ESRD interaction. Methods: The CAKs includes 30 hospitals which distribute widely through the four geographical regions (north, middle, south, and east) of Taiwan, and have a 1:1 ratio of medical centres to regional hospitals in each region. The NEP-AKI-D study enrols intensive care unit-based AKI patients who receive dialysis in the four seasonal sampled months (October 2014, along with January, April, and July 2015) in the included hospitals. The collected data include demographic information, pertaining laboratory results, dialysis settings and patient outcomes. The data are uploaded in a centre website and will be audited by on-site principal investigators, computer logic gates, and the CAKs staffs. The outcomes of interest are in-hospital mortality, dialysis-dependency and readmission rate within 90 days after discharge. Conclusion: The NEP-AKI-D study enrols a large number of representative AKI patients throughout Taiwan. The results of the current study are expected to provide more insight into the risk and prognostic factors of AKI and further attenuated further chronic kidney disease transition.

Original languageEnglish
Pages (from-to)758-764
Number of pages7
JournalNephrology
Volume21
Issue number9
DOIs
Publication statusPublished - Sep 1 2016

Fingerprint

Acute Kidney Injury
Dialysis
Epidemiology
Taiwan
Chronic Kidney Failure
Middle East
Incidence
Hospital Mortality
Chronic Renal Insufficiency
Critical Illness
Intensive Care Units
Research Personnel
Demography
Kidney

Keywords

  • acute kidney injury
  • dialysis
  • dialysis-dependency
  • end-stage renal disease
  • in-hospital mortality

ASJC Scopus subject areas

  • Medicine(all)
  • Nephrology

Cite this

on behalf of the Taiwan Consortium for Acute Kidney Injury Renal Diseases (CAKs) (2016). Nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study: Design and methods. Nephrology, 21(9), 758-764. https://doi.org/10.1111/nep.12670

Nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study : Design and methods. / on behalf of the Taiwan Consortium for Acute Kidney Injury Renal Diseases (CAKs).

In: Nephrology, Vol. 21, No. 9, 01.09.2016, p. 758-764.

Research output: Contribution to journalArticle

on behalf of the Taiwan Consortium for Acute Kidney Injury Renal Diseases (CAKs) 2016, 'Nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study: Design and methods', Nephrology, vol. 21, no. 9, pp. 758-764. https://doi.org/10.1111/nep.12670
on behalf of the Taiwan Consortium for Acute Kidney Injury Renal Diseases (CAKs). Nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study: Design and methods. Nephrology. 2016 Sep 1;21(9):758-764. https://doi.org/10.1111/nep.12670
on behalf of the Taiwan Consortium for Acute Kidney Injury Renal Diseases (CAKs). / Nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study : Design and methods. In: Nephrology. 2016 ; Vol. 21, No. 9. pp. 758-764.
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AU - Wu, Pei Chen

AU - Wu, Vin Cent

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AU - Yang, Ya Fei

AU - Lai, Tai Shuan

AU - Huang, Tao Min

AU - Wu, Che Hsiung

AU - Yang, Wei Shun

AU - Wu, Chih Jen

AU - Kao, Chih Chin

AU - Sun, Chiao Yin

AU - Huang, Chun Te

AU - Lee, Kuo Hua

AU - Lin, Chan Yu

AU - Chen, Te Chuan

AU - Hu, Fu Chang

AU - Liou, Hung Hsiang

AU - Lu, Kuo Cheng

AU - Chien, Kuo Liong

AU - Wang, Jian Jhong

AU - Kan, Wei Chih

AU - Kuo, Feng Chi

AU - Lin, Hugo You Hsien

AU - Chen, Cheng Min

AU - You, Zi Hong

AU - Tsai, Jen Pi

AU - Weng, Chih Jen

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AU - Chang, Chao Fu

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N2 - Aim: Acute kidney injury (AKI) carries an increasing incidence rate worldwide and increases the risk of developing end-stage renal disease (ESRD) as well as the medical expenses during the post-AKI course. The Taiwan Consortium for Acute Kidney Injury and Renal Diseases (CAKs) has thus launched a nationwide epidemiology and prognosis of dialysis-requiring acute kidney injury (NEP-AKI-D) study, which prospectively enrols critically ill patients with AKI. Through thoroughly evaluating the risk and prognostic factors of AKI, we hope to lower the incidence of AKI and ESRD from the perspective of AKI-ESRD interaction. Methods: The CAKs includes 30 hospitals which distribute widely through the four geographical regions (north, middle, south, and east) of Taiwan, and have a 1:1 ratio of medical centres to regional hospitals in each region. The NEP-AKI-D study enrols intensive care unit-based AKI patients who receive dialysis in the four seasonal sampled months (October 2014, along with January, April, and July 2015) in the included hospitals. The collected data include demographic information, pertaining laboratory results, dialysis settings and patient outcomes. The data are uploaded in a centre website and will be audited by on-site principal investigators, computer logic gates, and the CAKs staffs. The outcomes of interest are in-hospital mortality, dialysis-dependency and readmission rate within 90 days after discharge. Conclusion: The NEP-AKI-D study enrols a large number of representative AKI patients throughout Taiwan. The results of the current study are expected to provide more insight into the risk and prognostic factors of AKI and further attenuated further chronic kidney disease transition.

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KW - acute kidney injury

KW - dialysis

KW - dialysis-dependency

KW - end-stage renal disease

KW - in-hospital mortality

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