National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Po Yu Liu; Yu Lin Lee; Min Chi Lu; Pei Lan Shao; Po Liang Lu; Yen Hsu Chen; Shu Hsing Cheng; Wen Chien Ko; Chi Ying Lin; Ting Shu Wu; Muh Yong Yen; Lih Shinn Wang; Chang Pan Liu; Wen Sen Lee; Yao Shen Chen; Fu Der Wang; Shu Hui Tseng; Chao Nan Lin; Hung Jen Tang; Yu Hui Chen; Wang Huei Sheng; Chun Ming Lee; Ming Huei Liao; Po Ren Hsueh

doi:10.1128/AAC.01089-20

National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Po Yu Liu, Yu Lin Lee, Min Chi Lu, Pei Lan Shao, Po Liang Lu, Yen Hsu Chen, Shu Hsing Cheng, Wen Chien Ko, Chi Ying Lin, Ting Shu Wu, Muh Yong Yen, Lih Shinn Wang, Chang Pan Liu, Wen Sen Lee, Yao Shen Chen, Fu Der Wang, Shu Hui Tseng, Chao Nan Lin, Hung Jen Tang, Yu Hui ChenWang Huei Sheng, Chun Ming Lee, Ming Huei Liao, Po Ren Hsueh

Research output: Contribution to journal › Article

Abstract

A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.

Original language	English
Journal	Antimicrobial Agents and Chemotherapy
Volume	64
Issue number	10
DOIs	https://doi.org/10.1128/AAC.01089-20
Publication status	Published - Sep 21 2020

Keywords

carbapenemases
colistin
Enterobacteriaceae
KPC
mcr-1

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

Access to Document

10.1128/AAC.01089-20

Fingerprint Dive into the research topics of 'National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)'. Together they form a unique fingerprint.

Cite this

Liu, P. Y., Lee, Y. L., Lu, M. C., Shao, P. L., Lu, P. L., Chen, Y. H., Cheng, S. H., Ko, W. C., Lin, C. Y., Wu, T. S., Yen, M. Y., Wang, L. S., Liu, C. P., Lee, W. S., Chen, Y. S., Wang, F. D., Tseng, S. H., Lin, C. N., Tang, H. J., ... Hsueh, P. R. (2020). National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Antimicrobial Agents and Chemotherapy, 64(10). https://doi.org/10.1128/AAC.01089-20

National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates : Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). / Liu, Po Yu; Lee, Yu Lin; Lu, Min Chi; Shao, Pei Lan; Lu, Po Liang; Chen, Yen Hsu; Cheng, Shu Hsing; Ko, Wen Chien; Lin, Chi Ying; Wu, Ting Shu; Yen, Muh Yong; Wang, Lih Shinn; Liu, Chang Pan; Lee, Wen Sen; Chen, Yao Shen; Wang, Fu Der; Tseng, Shu Hui; Lin, Chao Nan; Tang, Hung Jen; Chen, Yu Hui; Sheng, Wang Huei; Lee, Chun Ming; Liao, Ming Huei; Hsueh, Po Ren.

In: Antimicrobial Agents and Chemotherapy, Vol. 64, No. 10, 21.09.2020.

Research output: Contribution to journal › Article

Liu, PY, Lee, YL, Lu, MC, Shao, PL, Lu, PL, Chen, YH, Cheng, SH, Ko, WC, Lin, CY, Wu, TS, Yen, MY, Wang, LS, Liu, CP, Lee, WS, Chen, YS, Wang, FD, Tseng, SH, Lin, CN, Tang, HJ, Chen, YH, Sheng, WH, Lee, CM, Liao, MH & Hsueh, PR 2020, 'National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)', Antimicrobial Agents and Chemotherapy, vol. 64, no. 10. https://doi.org/10.1128/AAC.01089-20

Liu PY, Lee YL, Lu MC, Shao PL, Lu PL, Chen YH et al. National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Antimicrobial Agents and Chemotherapy. 2020 Sep 21;64(10). https://doi.org/10.1128/AAC.01089-20

Liu, Po Yu ; Lee, Yu Lin ; Lu, Min Chi ; Shao, Pei Lan ; Lu, Po Liang ; Chen, Yen Hsu ; Cheng, Shu Hsing ; Ko, Wen Chien ; Lin, Chi Ying ; Wu, Ting Shu ; Yen, Muh Yong ; Wang, Lih Shinn ; Liu, Chang Pan ; Lee, Wen Sen ; Chen, Yao Shen ; Wang, Fu Der ; Tseng, Shu Hui ; Lin, Chao Nan ; Tang, Hung Jen ; Chen, Yu Hui ; Sheng, Wang Huei ; Lee, Chun Ming ; Liao, Ming Huei ; Hsueh, Po Ren. / National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates : Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). In: Antimicrobial Agents and Chemotherapy. 2020 ; Vol. 64, No. 10.

@article{67d907a53e7d4393929345548d2f6b2e,

title = "National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)",

abstract = "A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.",

keywords = "carbapenemases, colistin, Enterobacteriaceae, KPC, mcr-1",

author = "Liu, {Po Yu} and Lee, {Yu Lin} and Lu, {Min Chi} and Shao, {Pei Lan} and Lu, {Po Liang} and Chen, {Yen Hsu} and Cheng, {Shu Hsing} and Ko, {Wen Chien} and Lin, {Chi Ying} and Wu, {Ting Shu} and Yen, {Muh Yong} and Wang, {Lih Shinn} and Liu, {Chang Pan} and Lee, {Wen Sen} and Chen, {Yao Shen} and Wang, {Fu Der} and Tseng, {Shu Hui} and Lin, {Chao Nan} and Tang, {Hung Jen} and Chen, {Yu Hui} and Sheng, {Wang Huei} and Lee, {Chun Ming} and Liao, {Ming Huei} and Hsueh, {Po Ren}",

year = "2020",

month = sep,

day = "21",

doi = "10.1128/AAC.01089-20",

language = "English",

volume = "64",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "10",

}

TY - JOUR

T1 - National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates

T2 - Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

AU - Liu, Po Yu

AU - Lee, Yu Lin

AU - Lu, Min Chi

AU - Shao, Pei Lan

AU - Lu, Po Liang

AU - Chen, Yen Hsu

AU - Cheng, Shu Hsing

AU - Ko, Wen Chien

AU - Lin, Chi Ying

AU - Wu, Ting Shu

AU - Yen, Muh Yong

AU - Wang, Lih Shinn

AU - Liu, Chang Pan

AU - Lee, Wen Sen

AU - Chen, Yao Shen

AU - Wang, Fu Der

AU - Tseng, Shu Hui

AU - Lin, Chao Nan

AU - Tang, Hung Jen

AU - Chen, Yu Hui

AU - Sheng, Wang Huei

AU - Lee, Chun Ming

AU - Liao, Ming Huei

AU - Hsueh, Po Ren

PY - 2020/9/21

Y1 - 2020/9/21

N2 - A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.

AB - A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.

KW - carbapenemases

KW - colistin

KW - Enterobacteriaceae

KW - KPC

KW - mcr-1

UR - http://www.scopus.com/inward/record.url?scp=85091469900&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85091469900&partnerID=8YFLogxK

U2 - 10.1128/AAC.01089-20

DO - 10.1128/AAC.01089-20

M3 - Article

C2 - 32690650

AN - SCOPUS:85091469900

VL - 64

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 10

ER -