National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Po Yu Liu; Yu Lin Lee; Min Chi Lu; Pei Lan Shao; Po Liang Lu; Yen Hsu Chen; Shu Hsing Cheng; Wen Chien Ko; Chi Ying Lin; Ting Shu Wu; Muh Yong Yen; Lih Shinn Wang; Chang Pan Liu; Wen Sen Lee; Yao Shen Chen; Fu Der Wang; Shu Hui Tseng; Chao Nan Lin; Hung Jen Tang; Yu Hui Chen; Wang Huei Sheng; Chun Ming Lee; Ming Huei Liao; Po Ren Hsueh

doi:10.1128/AAC.01089-20

National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Po Yu Liu, Yu Lin Lee, Min Chi Lu, Pei Lan Shao, Po Liang Lu, Yen Hsu Chen, Shu Hsing Cheng, Wen Chien Ko, Chi Ying Lin, Ting Shu Wu, Muh Yong Yen, Lih Shinn Wang, Chang Pan Liu, Wen Sen Lee, Yao Shen Chen, Fu Der Wang, Shu Hui Tseng, Chao Nan Lin, Hung Jen Tang, Yu Hui ChenWang Huei Sheng, Chun Ming Lee, Ming Huei Liao, Po Ren Hsueh

Research output: Contribution to journal › Article › peer-review

Abstract

A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.

Original language	English
Journal	Antimicrobial Agents and Chemotherapy
Volume	64
Issue number	10
DOIs	https://doi.org/10.1128/AAC.01089-20
Publication status	Published - Sep 21 2020

Keywords

carbapenemases
colistin
Enterobacteriaceae
KPC
mcr-1

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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Liu, P. Y., Lee, Y. L., Lu, M. C., Shao, P. L., Lu, P. L., Chen, Y. H., Cheng, S. H., Ko, W. C., Lin, C. Y., Wu, T. S., Yen, M. Y., Wang, L. S., Liu, C. P., Lee, W. S., Chen, Y. S., Wang, F. D., Tseng, S. H., Lin, C. N., Tang, H. J., ... Hsueh, P. R. (2020). National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Antimicrobial Agents and Chemotherapy, 64(10). https://doi.org/10.1128/AAC.01089-20

National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates : Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). / Liu, Po Yu; Lee, Yu Lin; Lu, Min Chi; Shao, Pei Lan; Lu, Po Liang; Chen, Yen Hsu; Cheng, Shu Hsing; Ko, Wen Chien; Lin, Chi Ying; Wu, Ting Shu; Yen, Muh Yong; Wang, Lih Shinn; Liu, Chang Pan; Lee, Wen Sen; Chen, Yao Shen; Wang, Fu Der; Tseng, Shu Hui; Lin, Chao Nan; Tang, Hung Jen; Chen, Yu Hui; Sheng, Wang Huei; Lee, Chun Ming; Liao, Ming Huei; Hsueh, Po Ren.

In: Antimicrobial Agents and Chemotherapy, Vol. 64, No. 10, 21.09.2020.

Research output: Contribution to journal › Article › peer-review

Liu, PY, Lee, YL, Lu, MC, Shao, PL, Lu, PL, Chen, YH, Cheng, SH, Ko, WC, Lin, CY, Wu, TS, Yen, MY, Wang, LS, Liu, CP, Lee, WS, Chen, YS, Wang, FD, Tseng, SH, Lin, CN, Tang, HJ, Chen, YH, Sheng, WH, Lee, CM, Liao, MH & Hsueh, PR 2020, 'National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)', Antimicrobial Agents and Chemotherapy, vol. 64, no. 10. https://doi.org/10.1128/AAC.01089-20

Liu PY, Lee YL, Lu MC, Shao PL, Lu PL, Chen YH et al. National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). Antimicrobial Agents and Chemotherapy. 2020 Sep 21;64(10). https://doi.org/10.1128/AAC.01089-20

Liu, Po Yu ; Lee, Yu Lin ; Lu, Min Chi ; Shao, Pei Lan ; Lu, Po Liang ; Chen, Yen Hsu ; Cheng, Shu Hsing ; Ko, Wen Chien ; Lin, Chi Ying ; Wu, Ting Shu ; Yen, Muh Yong ; Wang, Lih Shinn ; Liu, Chang Pan ; Lee, Wen Sen ; Chen, Yao Shen ; Wang, Fu Der ; Tseng, Shu Hui ; Lin, Chao Nan ; Tang, Hung Jen ; Chen, Yu Hui ; Sheng, Wang Huei ; Lee, Chun Ming ; Liao, Ming Huei ; Hsueh, Po Ren. / National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates : Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). In: Antimicrobial Agents and Chemotherapy. 2020 ; Vol. 64, No. 10.

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abstract = "A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored blaKPC (n = 17), blaOXA-48 (n = 2), and blaVIM (n = 1) genes.",

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