Nasal-type extranodal natural killer/t-cell lymphoma mimicking recurrent sinusitis: A case report and review of the literature

Cheng Fu Ni, Liang Kung Chen

Research output: Contribution to journalReview article


Nasal-type extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is a rare type of lymphoma that is endemic to East Asia. It typically demonstrates as a destructive mass involving the midline facial tissues that causes rhinosinusitis symptoms such as nasal obstruction, sinusitis, ulcer, and epistaxis. The diagnostic tendency of nasal-type ENKTL is to use computed tomography (CT), but this may present infiltrative patterns without a prominent mass, making it difficult to distinguish ENKTL from benign inflammatory diseases. Here, we report a 59-year-old male with a chief complaint of rhinosinusitis symptoms, mimicking chronic sinusitis and a CT scan showing a typical right sinusitis pattern. Functional endoscopic sinus surgery was performed and a positive culture was consistent with the diagnosis. However, histopathological and immunohistochemical evaluation established the diagnosis of nasal type ENKTL. Follow-up positron emission tomography-computed tomography (PET-CT) also corresponded with this diagnosis, and therefore, radiotherapy and chemotherapy were indicated.

Original languageEnglish
Article numbere33054
JournalIranian Journal of Radiology
Issue number2
Publication statusPublished - Apr 1 2017
Externally publishedYes



  • Computed tomography
  • Extranodal NK-T-Cell
  • Functional endoscopic sinus surgery
  • Lymphoma
  • Sinusitis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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