Nasal-type extranodal natural killer/t-cell lymphoma mimicking recurrent sinusitis: A case report and review of the literature

Cheng Fu Ni, Liang Kung Chen

Research output: Contribution to journalReview article

Abstract

Nasal-type extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is a rare type of lymphoma that is endemic to East Asia. It typically demonstrates as a destructive mass involving the midline facial tissues that causes rhinosinusitis symptoms such as nasal obstruction, sinusitis, ulcer, and epistaxis. The diagnostic tendency of nasal-type ENKTL is to use computed tomography (CT), but this may present infiltrative patterns without a prominent mass, making it difficult to distinguish ENKTL from benign inflammatory diseases. Here, we report a 59-year-old male with a chief complaint of rhinosinusitis symptoms, mimicking chronic sinusitis and a CT scan showing a typical right sinusitis pattern. Functional endoscopic sinus surgery was performed and a positive culture was consistent with the diagnosis. However, histopathological and immunohistochemical evaluation established the diagnosis of nasal type ENKTL. Follow-up positron emission tomography-computed tomography (PET-CT) also corresponded with this diagnosis, and therefore, radiotherapy and chemotherapy were indicated.

Original languageEnglish
Article numbere33054
JournalIranian Journal of Radiology
Volume14
Issue number2
DOIs
Publication statusPublished - Apr 1 2017
Externally publishedYes

Fingerprint

Sinusitis
Nose
Natural Killer Cells
Lymphoma
Tomography
Nasal Obstruction
Epistaxis
Natural Killer T-Cells
Far East
T-Cell Lymphoma
Ulcer
Radiotherapy
Drug Therapy

Keywords

  • Computed tomography
  • Extranodal NK-T-Cell
  • Functional endoscopic sinus surgery
  • Lymphoma
  • Sinusitis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Nasal-type extranodal natural killer/t-cell lymphoma mimicking recurrent sinusitis : A case report and review of the literature. / Ni, Cheng Fu; Chen, Liang Kung.

In: Iranian Journal of Radiology, Vol. 14, No. 2, e33054, 01.04.2017.

Research output: Contribution to journalReview article

@article{b8439ef7021e4cc2a3c111954c0ba8bf,
title = "Nasal-type extranodal natural killer/t-cell lymphoma mimicking recurrent sinusitis: A case report and review of the literature",
abstract = "Nasal-type extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is a rare type of lymphoma that is endemic to East Asia. It typically demonstrates as a destructive mass involving the midline facial tissues that causes rhinosinusitis symptoms such as nasal obstruction, sinusitis, ulcer, and epistaxis. The diagnostic tendency of nasal-type ENKTL is to use computed tomography (CT), but this may present infiltrative patterns without a prominent mass, making it difficult to distinguish ENKTL from benign inflammatory diseases. Here, we report a 59-year-old male with a chief complaint of rhinosinusitis symptoms, mimicking chronic sinusitis and a CT scan showing a typical right sinusitis pattern. Functional endoscopic sinus surgery was performed and a positive culture was consistent with the diagnosis. However, histopathological and immunohistochemical evaluation established the diagnosis of nasal type ENKTL. Follow-up positron emission tomography-computed tomography (PET-CT) also corresponded with this diagnosis, and therefore, radiotherapy and chemotherapy were indicated.",
keywords = "Computed tomography, Extranodal NK-T-Cell, Functional endoscopic sinus surgery, Lymphoma, Sinusitis, Computed tomography, Extranodal NK-T-Cell, Functional endoscopic sinus surgery, Lymphoma, Sinusitis",
author = "Ni, {Cheng Fu} and Chen, {Liang Kung}",
year = "2017",
month = "4",
day = "1",
doi = "10.5812/iranjradiol.33054",
language = "English",
volume = "14",
journal = "Iranian Journal of Radiology",
issn = "1735-1065",
publisher = "Kowsar Publishing Company",
number = "2",

}

TY - JOUR

T1 - Nasal-type extranodal natural killer/t-cell lymphoma mimicking recurrent sinusitis

T2 - A case report and review of the literature

AU - Ni, Cheng Fu

AU - Chen, Liang Kung

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Nasal-type extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is a rare type of lymphoma that is endemic to East Asia. It typically demonstrates as a destructive mass involving the midline facial tissues that causes rhinosinusitis symptoms such as nasal obstruction, sinusitis, ulcer, and epistaxis. The diagnostic tendency of nasal-type ENKTL is to use computed tomography (CT), but this may present infiltrative patterns without a prominent mass, making it difficult to distinguish ENKTL from benign inflammatory diseases. Here, we report a 59-year-old male with a chief complaint of rhinosinusitis symptoms, mimicking chronic sinusitis and a CT scan showing a typical right sinusitis pattern. Functional endoscopic sinus surgery was performed and a positive culture was consistent with the diagnosis. However, histopathological and immunohistochemical evaluation established the diagnosis of nasal type ENKTL. Follow-up positron emission tomography-computed tomography (PET-CT) also corresponded with this diagnosis, and therefore, radiotherapy and chemotherapy were indicated.

AB - Nasal-type extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is a rare type of lymphoma that is endemic to East Asia. It typically demonstrates as a destructive mass involving the midline facial tissues that causes rhinosinusitis symptoms such as nasal obstruction, sinusitis, ulcer, and epistaxis. The diagnostic tendency of nasal-type ENKTL is to use computed tomography (CT), but this may present infiltrative patterns without a prominent mass, making it difficult to distinguish ENKTL from benign inflammatory diseases. Here, we report a 59-year-old male with a chief complaint of rhinosinusitis symptoms, mimicking chronic sinusitis and a CT scan showing a typical right sinusitis pattern. Functional endoscopic sinus surgery was performed and a positive culture was consistent with the diagnosis. However, histopathological and immunohistochemical evaluation established the diagnosis of nasal type ENKTL. Follow-up positron emission tomography-computed tomography (PET-CT) also corresponded with this diagnosis, and therefore, radiotherapy and chemotherapy were indicated.

KW - Computed tomography

KW - Extranodal NK-T-Cell

KW - Functional endoscopic sinus surgery

KW - Lymphoma

KW - Sinusitis

KW - Computed tomography

KW - Extranodal NK-T-Cell

KW - Functional endoscopic sinus surgery

KW - Lymphoma

KW - Sinusitis

UR - http://www.scopus.com/inward/record.url?scp=85027582554&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85027582554&partnerID=8YFLogxK

U2 - 10.5812/iranjradiol.33054

DO - 10.5812/iranjradiol.33054

M3 - Review article

AN - SCOPUS:85027582554

VL - 14

JO - Iranian Journal of Radiology

JF - Iranian Journal of Radiology

SN - 1735-1065

IS - 2

M1 - e33054

ER -