Myeloblastic leukemoid reaction in paroxysmal nocturnal hemoglobinuria associated with myelodysplasia

W. S. Ko, L. M. Chen, T. Y. Chao, W. S. Hwang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) has been observed to evolve into myelofibrosis and acute myeloid leukemia. Myeloblastic leukemoid reaction has not been described in PNH. We described a patient with PNH with myelodysplasia and septicemia. The marrow aspirates showed a picture of myeloblastosis which subsided when sepsis was controlled. The myeloblastic leukemoid reaction in our patient related to overwhelming sepsis, splenectomy and overt hemolysis.

Original languageEnglish
Pages (from-to)75-77
Number of pages3
JournalActa Haematologica
Volume87
Issue number1-2
Publication statusPublished - 1992
Externally publishedYes

Keywords

  • Myeloblastic leukemoid reaction
  • Paroxysmal nocturnal hemoglobinuria

ASJC Scopus subject areas

  • Hematology

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