Mycobacteriosis in patients with fever of unknown origin

Chuen Chin, S. S J Lee, Yao Shen Chen, Shue R. Wann, Hsi Hsun Lin, Wei R. Lin, Chun K. Huang, Chih Hsiang Kao, Muh Yong Yen, Yung Ching Liu

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Fever of unknown origin (FUO) is a common syndrome. A total of 94 patients (57 men and 37 women; mean age, 56.3 ± 19 years, range, 18-86 years) who met the criteria of FUO were included in this study. Mycobacteriosis was diagnosed in 22 (23%) of these patients (13 men and 9 women), including 9 with disseminated disease and 13 with pulmonary disease. There was no significant statistical difference in age, sex, short-term survival status (3 months), and other clinical parameters between patients with and without mycobacteriosis. Clinical manifestations may be specific or nonspecific. The most common initial presentations in patients with mycobacteriosis were respiratory tract symptoms, mainly of cough and dyspnea, observed in 11 (50%) patients, and disturbance of consciousness in 6 (27%). The associated conditions included malnutrition (4 patients, 18%), diabetes mellitus (3, 14%), and renal failure (3, 14%). Four (18%) patients had a history of pulmonary tuberculosis or tuberculous spondylitis in their early adulthood. The 2 most common findings on chest radiograph were interstitial (41%) and nonspecific infiltrative (32%) patterns. In conclusion, mycobacteriosis remains the leading cause of FUO in southern Taiwan and it is important to screen for this treatable disease in all cases of FUO.

Original languageEnglish
Pages (from-to)248-253
Number of pages6
JournalJournal of Microbiology, Immunology and Infection
Volume36
Issue number4
Publication statusPublished - Dec 2003
Externally publishedYes

Fingerprint

Fever of Unknown Origin
Spondylitis
Consciousness
Taiwan
Pulmonary Tuberculosis
Cough
Malnutrition
Respiratory System
Dyspnea
Lung Diseases
Renal Insufficiency
Diabetes Mellitus
Thorax
Survival

Keywords

  • Fever of unknown origin
  • Mycobacterial infection
  • Tuberculosis

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Chin, C., Lee, S. S. J., Chen, Y. S., Wann, S. R., Lin, H. H., Lin, W. R., ... Liu, Y. C. (2003). Mycobacteriosis in patients with fever of unknown origin. Journal of Microbiology, Immunology and Infection, 36(4), 248-253.

Mycobacteriosis in patients with fever of unknown origin. / Chin, Chuen; Lee, S. S J; Chen, Yao Shen; Wann, Shue R.; Lin, Hsi Hsun; Lin, Wei R.; Huang, Chun K.; Kao, Chih Hsiang; Yen, Muh Yong; Liu, Yung Ching.

In: Journal of Microbiology, Immunology and Infection, Vol. 36, No. 4, 12.2003, p. 248-253.

Research output: Contribution to journalArticle

Chin, C, Lee, SSJ, Chen, YS, Wann, SR, Lin, HH, Lin, WR, Huang, CK, Kao, CH, Yen, MY & Liu, YC 2003, 'Mycobacteriosis in patients with fever of unknown origin', Journal of Microbiology, Immunology and Infection, vol. 36, no. 4, pp. 248-253.
Chin C, Lee SSJ, Chen YS, Wann SR, Lin HH, Lin WR et al. Mycobacteriosis in patients with fever of unknown origin. Journal of Microbiology, Immunology and Infection. 2003 Dec;36(4):248-253.
Chin, Chuen ; Lee, S. S J ; Chen, Yao Shen ; Wann, Shue R. ; Lin, Hsi Hsun ; Lin, Wei R. ; Huang, Chun K. ; Kao, Chih Hsiang ; Yen, Muh Yong ; Liu, Yung Ching. / Mycobacteriosis in patients with fever of unknown origin. In: Journal of Microbiology, Immunology and Infection. 2003 ; Vol. 36, No. 4. pp. 248-253.
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