Mutagenicity of particulates from the laboratory combustion of plastics

Huei Lee, Lee Wang, Jung Feng Shih

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Carcinogenic polycyclic aromatic hydrocarbons (PAHs) and nitropolycyclic aromatic hydrocarbons (nitro-PAHs) have been identified in airborne particulate organic matter extracts. The pollutant sources were generally contributed by motor vehicles and industrial activity. Massive quantities of urban solid wastes, containing plastic materials such as PVC, PET, PS, and PE, burnt in the open air in local garbage dumps are frequently found in developing countries. In this study, the smog particulates from the combustion of these synthetic polymers were produced in a laboratory combustion chamber. The mutagenicity of acetone extracts from the smog particulates was evaluated with Salmonella typhimurium TA98 and TA100 in the presence and absence of S9 mix. Four samples in TA98 exhibited higher mutagenicity than those in TA100. The greatest mutagenicity was observed from the extracts of particulates from combustion of PVC followed by that of PS, PET, and PE. To determine the major mutagenic compounds in these samples, mutagens were partially purified through TLC and their mutagenicity was monitored with TA98. 1-NP and DNPs in the above samples were also determined by HPLC. The amounts of 1-NP and DNPs generally corresponded with their mutagenicity. Higher levels of 1-NP and DNPS from the combustion of PVC, PET, and PS. the combustion of synthetic polymer wastes might be responsible for the presence of high levels of 1-NP and DNPs in Taiwan urban air.

Original languageEnglish
Pages (from-to)135-144
Number of pages10
JournalMutation Research Letters
Volume346
Issue number3
DOIs
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Smog
Polyvinyl Chloride
Plastics
Polymers
Air
Garbage
Solid Waste
Aromatic Hydrocarbons
Particulate Matter
Polycyclic Aromatic Hydrocarbons
Mutagens
Motor Vehicles
Salmonella typhimurium
Acetone
Taiwan
Developing Countries
Salmonella
Solid wastes
Combustion chambers
High Pressure Liquid Chromatography

Keywords

  • Nitropyrene
  • Plastic combustion
  • Polycyclic aromatic hydrocarbon

ASJC Scopus subject areas

  • Genetics
  • Toxicology

Cite this

Mutagenicity of particulates from the laboratory combustion of plastics. / Lee, Huei; Wang, Lee; Shih, Jung Feng.

In: Mutation Research Letters, Vol. 346, No. 3, 1995, p. 135-144.

Research output: Contribution to journalArticle

Lee, Huei ; Wang, Lee ; Shih, Jung Feng. / Mutagenicity of particulates from the laboratory combustion of plastics. In: Mutation Research Letters. 1995 ; Vol. 346, No. 3. pp. 135-144.
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