Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck

陳 海雯(Helen Hw Chen), 方 麗麗, 丁 禮莉(Lai-Lei Ting), 梁 永昌(Henry Wc Leung), 雷 德, 黃 淑珍

Research output: Contribution to journalArticle

1 Downloads (Pure)

Abstract

Patients with cancer of the head and neck have been described to be particularly susceptible to the development of new cancers. To help our understanding of this issue, we evaluated all head and neck patients with multiple primary cancers in National Taiwan University Hospital (NTUH). A retrospective chart review with correlation of cancer registry records showed that second primary malignancies developed in 136 patients till Dec. 1991. Five of them had three separate cancers. Ninety eight of 136 had their first head and neck primary during 1977-1991 among 7,475 patients, providing the occurrence rate of 1.31%. The other 38 patients had their first cancer diagnosed before 1977. The median time to the development of a second malignant tumor was 4.58 years, with a maximum interval of 29.75 years. Most of the patients (110 in 136) developed a second cancer metachronously. A total of 91 (66.9%) patients had their second cancer in the head and neck, esophagus or lung. Second primary malignancies were most commonly associated with nasopharyngeal index tumors (62 in 136), nearly all of which (60 in 62) received radiation therapy; followed by laryngeal cancers (25 in 136), of which 16 had radiation therapy or surgery plus radiation therapy. In both nasopharyngeal and laryngeal index tumor groups, head and neck region was the most common site of multiple primary cancers.
Original languageEnglish
Pages (from-to)11-18
Number of pages8
JournalChinese Journal of Radiology
Volume19
Issue number1
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Head and Neck Neoplasms
Taiwan
Second Primary Neoplasms
Neoplasms
Neck
Radiotherapy
Head
Laryngeal Neoplasms
Esophagus
Registries
Lung

Keywords

  • 頭頸部腫瘤
  • 頭頸部腫瘤之放射治療學
  • Head and neck neoplasms
  • head and neck neoplasms, therapeutic radiology

Cite this

陳海雯(Helen H C, 方麗麗, 丁禮莉(Lai-Lei T, 梁永昌(Henry W L, 雷德, & 黃淑珍 (1994). Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck. Chinese Journal of Radiology, 19(1), 11-18.

Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck. / 陳海雯(Helen Hw Chen); 方麗麗; 丁禮莉(Lai-Lei Ting); 梁永昌(Henry Wc Leung); 雷德; 黃淑珍.

In: Chinese Journal of Radiology, Vol. 19, No. 1, 1994, p. 11-18.

Research output: Contribution to journalArticle

陳海雯(HelenHC, 方麗麗, 丁禮莉(Lai-LeiT, 梁永昌(HenryWL, 雷德 & 黃淑珍 1994, 'Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck', Chinese Journal of Radiology, vol. 19, no. 1, pp. 11-18.
陳海雯(HelenHC, 方麗麗, 丁禮莉(Lai-LeiT, 梁永昌(HenryWL, 雷德, 黃淑珍. Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck. Chinese Journal of Radiology. 1994;19(1):11-18.
陳海雯(Helen Hw Chen) ; 方麗麗 ; 丁禮莉(Lai-Lei Ting) ; 梁永昌(Henry Wc Leung) ; 雷德 ; 黃淑珍. / Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck. In: Chinese Journal of Radiology. 1994 ; Vol. 19, No. 1. pp. 11-18.
@article{8c0dac3c597f415c8ad3e2e758477bf1,
title = "Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck",
abstract = "Patients with cancer of the head and neck have been described to be particularly susceptible to the development of new cancers. To help our understanding of this issue, we evaluated all head and neck patients with multiple primary cancers in National Taiwan University Hospital (NTUH). A retrospective chart review with correlation of cancer registry records showed that second primary malignancies developed in 136 patients till Dec. 1991. Five of them had three separate cancers. Ninety eight of 136 had their first head and neck primary during 1977-1991 among 7,475 patients, providing the occurrence rate of 1.31{\%}. The other 38 patients had their first cancer diagnosed before 1977. The median time to the development of a second malignant tumor was 4.58 years, with a maximum interval of 29.75 years. Most of the patients (110 in 136) developed a second cancer metachronously. A total of 91 (66.9{\%}) patients had their second cancer in the head and neck, esophagus or lung. Second primary malignancies were most commonly associated with nasopharyngeal index tumors (62 in 136), nearly all of which (60 in 62) received radiation therapy; followed by laryngeal cancers (25 in 136), of which 16 had radiation therapy or surgery plus radiation therapy. In both nasopharyngeal and laryngeal index tumor groups, head and neck region was the most common site of multiple primary cancers.",
keywords = "頭頸部腫瘤, 頭頸部腫瘤之放射治療學, Head and neck neoplasms, head and neck neoplasms, therapeutic radiology, Head and Neck Neoplasms, Therapeutic radiology",
author = "陳, {海雯(Helen Hw Chen)} and 麗麗 方 and 丁, {禮莉(Lai-Lei Ting)} and 梁, {永昌(Henry Wc Leung)} and 德 雷 and 淑珍 黃",
year = "1994",
language = "English",
volume = "19",
pages = "11--18",
journal = "Chinese Journal of Radiology",
issn = "1018-8940",
publisher = "中華民國放射線醫學會",
number = "1",

}

TY - JOUR

T1 - Multiple Primary Cancers in NTUH Patients with Cancer of the Head and Neck

AU - 陳, 海雯(Helen Hw Chen)

AU - 方, 麗麗

AU - 丁, 禮莉(Lai-Lei Ting)

AU - 梁, 永昌(Henry Wc Leung)

AU - 雷, 德

AU - 黃, 淑珍

PY - 1994

Y1 - 1994

N2 - Patients with cancer of the head and neck have been described to be particularly susceptible to the development of new cancers. To help our understanding of this issue, we evaluated all head and neck patients with multiple primary cancers in National Taiwan University Hospital (NTUH). A retrospective chart review with correlation of cancer registry records showed that second primary malignancies developed in 136 patients till Dec. 1991. Five of them had three separate cancers. Ninety eight of 136 had their first head and neck primary during 1977-1991 among 7,475 patients, providing the occurrence rate of 1.31%. The other 38 patients had their first cancer diagnosed before 1977. The median time to the development of a second malignant tumor was 4.58 years, with a maximum interval of 29.75 years. Most of the patients (110 in 136) developed a second cancer metachronously. A total of 91 (66.9%) patients had their second cancer in the head and neck, esophagus or lung. Second primary malignancies were most commonly associated with nasopharyngeal index tumors (62 in 136), nearly all of which (60 in 62) received radiation therapy; followed by laryngeal cancers (25 in 136), of which 16 had radiation therapy or surgery plus radiation therapy. In both nasopharyngeal and laryngeal index tumor groups, head and neck region was the most common site of multiple primary cancers.

AB - Patients with cancer of the head and neck have been described to be particularly susceptible to the development of new cancers. To help our understanding of this issue, we evaluated all head and neck patients with multiple primary cancers in National Taiwan University Hospital (NTUH). A retrospective chart review with correlation of cancer registry records showed that second primary malignancies developed in 136 patients till Dec. 1991. Five of them had three separate cancers. Ninety eight of 136 had their first head and neck primary during 1977-1991 among 7,475 patients, providing the occurrence rate of 1.31%. The other 38 patients had their first cancer diagnosed before 1977. The median time to the development of a second malignant tumor was 4.58 years, with a maximum interval of 29.75 years. Most of the patients (110 in 136) developed a second cancer metachronously. A total of 91 (66.9%) patients had their second cancer in the head and neck, esophagus or lung. Second primary malignancies were most commonly associated with nasopharyngeal index tumors (62 in 136), nearly all of which (60 in 62) received radiation therapy; followed by laryngeal cancers (25 in 136), of which 16 had radiation therapy or surgery plus radiation therapy. In both nasopharyngeal and laryngeal index tumor groups, head and neck region was the most common site of multiple primary cancers.

KW - 頭頸部腫瘤

KW - 頭頸部腫瘤之放射治療學

KW - Head and neck neoplasms

KW - head and neck neoplasms, therapeutic radiology

KW - Head and Neck Neoplasms

KW - Therapeutic radiology

M3 - Article

VL - 19

SP - 11

EP - 18

JO - Chinese Journal of Radiology

JF - Chinese Journal of Radiology

SN - 1018-8940

IS - 1

ER -