Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

Wei Chen Huang, Hsin Yi Lai, Li Wei Kuo, Chia Hsin Liao, Po Hsieh Chang, Ta Chung Liu, San Yuan Chen, You Yin Chen

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

Original languageEnglish
Pages (from-to)4186-4193
Number of pages8
JournalAdvanced Materials
Volume27
Issue number28
DOIs
Publication statusPublished - Jul 1 2015
Externally publishedYes

Fingerprint

Nanostructured materials
Neurons
Structural properties
Brain
Anti-Inflammatory Agents
Tissue
Mechanical properties
Pharmaceutical Preparations

Keywords

  • drug delivery
  • hydrogel
  • nanocarrier(s)
  • neural implant
  • neural interface

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation. / Huang, Wei Chen; Lai, Hsin Yi; Kuo, Li Wei; Liao, Chia Hsin; Chang, Po Hsieh; Liu, Ta Chung; Chen, San Yuan; Chen, You Yin.

In: Advanced Materials, Vol. 27, No. 28, 01.07.2015, p. 4186-4193.

Research output: Contribution to journalArticle

Huang, Wei Chen ; Lai, Hsin Yi ; Kuo, Li Wei ; Liao, Chia Hsin ; Chang, Po Hsieh ; Liu, Ta Chung ; Chen, San Yuan ; Chen, You Yin. / Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation. In: Advanced Materials. 2015 ; Vol. 27, No. 28. pp. 4186-4193.
@article{afc2f013dbf74fcb993a82e51b1a5f7e,
title = "Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation",
abstract = "To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.",
keywords = "drug delivery, hydrogel, nanocarrier(s), neural implant, neural interface",
author = "Huang, {Wei Chen} and Lai, {Hsin Yi} and Kuo, {Li Wei} and Liao, {Chia Hsin} and Chang, {Po Hsieh} and Liu, {Ta Chung} and Chen, {San Yuan} and Chen, {You Yin}",
year = "2015",
month = "7",
day = "1",
doi = "10.1002/adma.201500136",
language = "English",
volume = "27",
pages = "4186--4193",
journal = "Advanced Materials",
issn = "0935-9648",
publisher = "Wiley-VCH Verlag",
number = "28",

}

TY - JOUR

T1 - Multifunctional 3D Patternable Drug-Embedded Nanocarrier-Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation

AU - Huang, Wei Chen

AU - Lai, Hsin Yi

AU - Kuo, Li Wei

AU - Liao, Chia Hsin

AU - Chang, Po Hsieh

AU - Liu, Ta Chung

AU - Chen, San Yuan

AU - Chen, You Yin

PY - 2015/7/1

Y1 - 2015/7/1

N2 - To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

AB - To improve the long-term performance of a neural implant, a nanocarrier-based neural interface is developed by implementing nanomanufacturing technology and multifunctional nanomaterials to provide structural and mechanical properties that mimic brain tissue, sustain the nonfouling property, and prolong the anti-inflammatory ability.

KW - drug delivery

KW - hydrogel

KW - nanocarrier(s)

KW - neural implant

KW - neural interface

UR - http://www.scopus.com/inward/record.url?scp=84937142072&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84937142072&partnerID=8YFLogxK

U2 - 10.1002/adma.201500136

DO - 10.1002/adma.201500136

M3 - Article

C2 - 26074252

AN - SCOPUS:84937142072

VL - 27

SP - 4186

EP - 4193

JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

IS - 28

ER -