Multidrug-resistant tuberculosis (MDR-TB) is defined by bacillary resistant to at least isoniazid and rifampicin in vitro. Although a great diversity of reasons accounting for MDR-TB, poor treatment adherence of patient or inappropriate prescription of physicians are still the major causes. Implementation of DOTS (directly observed therapy, short-course) could decrease incidence of MDR-TB. For MDR-TB, prevention is best strategy. Besides, implantation of DOTS-plus also could increase cure rate. To build efficacious framework system for managing tuberculosis is an important issue to prevent and treat MDR-TB.
- Multidrug-resistant tuberculosis
- Directly observed therapy, short-course