Multidrug-resistant non-typhoid Salmonella infections in a medical center

Chien Yu Lee, Cheng Hsun Chiu, Yu Yu Chuang, Lin Hui Su, Tsu Lan Wu, Luan Yin Chang, Yhu Chering Huang, Tzou Yien Lin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Due to the high incidence of antimicrobial-resistant Salmonella in Taiwan, the emergence of multidrug-resistant Salmonella has become of particular concern. This retrospective study assessed the clinical features of patients with multidrug-resistant Salmonella treated from January 1998 through June 2000. A total of 201 children and 33 adults with multidrug-resistant Salmonella infections treated during a 2.5-year period were included. Sixty-percent of these patients had used antibiotics before multidrug-resistant Salmonella infection developed. The incidence of extra-intestinal infections was higher in adults (51.4%) than in children (4.9%). Infection with an invasive serotype of Salmonella, such as Salmonella choleraesuis, and host factors appeared to be predisposing factors for bacteremia or extra-intestinal infections. None of the patients had mortality attributable to multidrug-resistant salmonellosis. The increasing rate of resistance to third-generation cephalosporins and fluoroquinolones and the high multidrug-resistant rate of S. choleraesuis found in this study indicate the importance of judicious use of antimicrobial agents in both humans and animals to reduce the selection and spread of resistant strains.

Original languageEnglish
Pages (from-to)78-84
Number of pages7
JournalJournal of Microbiology, Immunology and Infection
Volume35
Issue number2
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Salmonella Infections
Salmonella
Infection
Fluoroquinolones
Incidence
Cephalosporins
Bacteremia
Anti-Infective Agents
Taiwan
Causality
Retrospective Studies
Anti-Bacterial Agents
Mortality

Keywords

  • Extra-intestinal infection
  • Multidrug-resistant Salmonella

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Lee, C. Y., Chiu, C. H., Chuang, Y. Y., Su, L. H., Wu, T. L., Chang, L. Y., ... Lin, T. Y. (2002). Multidrug-resistant non-typhoid Salmonella infections in a medical center. Journal of Microbiology, Immunology and Infection, 35(2), 78-84.

Multidrug-resistant non-typhoid Salmonella infections in a medical center. / Lee, Chien Yu; Chiu, Cheng Hsun; Chuang, Yu Yu; Su, Lin Hui; Wu, Tsu Lan; Chang, Luan Yin; Huang, Yhu Chering; Lin, Tzou Yien.

In: Journal of Microbiology, Immunology and Infection, Vol. 35, No. 2, 2002, p. 78-84.

Research output: Contribution to journalArticle

Lee, CY, Chiu, CH, Chuang, YY, Su, LH, Wu, TL, Chang, LY, Huang, YC & Lin, TY 2002, 'Multidrug-resistant non-typhoid Salmonella infections in a medical center', Journal of Microbiology, Immunology and Infection, vol. 35, no. 2, pp. 78-84.
Lee, Chien Yu ; Chiu, Cheng Hsun ; Chuang, Yu Yu ; Su, Lin Hui ; Wu, Tsu Lan ; Chang, Luan Yin ; Huang, Yhu Chering ; Lin, Tzou Yien. / Multidrug-resistant non-typhoid Salmonella infections in a medical center. In: Journal of Microbiology, Immunology and Infection. 2002 ; Vol. 35, No. 2. pp. 78-84.
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