Multicentric reticulohistiocytosis in a Taiwanese woman with Sjögren syndrome

Lan hsin Cheng, Ying Yi Chiang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Multicentric reticulohistiocytosis is a rare, non-Langerhans cell histiocytosis characterized by specific skin lesions and destructive arthritis. Clinically, it generally presents with multiple reddish-brown papulonodules over the hands, face, and trunk. The associated destructive arthropathy tends to be severe, with 50% of patients developing arthritis mutilans. Approximately 25-30% of patients present with neoplasia. Coexisting autoimmune diseases are also commonly reported. Here we report the case of a 59-year-old Taiwanese woman with underlying Sjögren syndrome who presented with the typical skin manifestations of multicentric reticulohistiocytosis and early interphalangeal joint involvement. The patient later showed partial response to methotrexate treatment.

Original languageEnglish
Pages (from-to)42-45
JournalDermatologica Sinica
Volume34
Issue number1
DOIs
Publication statusPublished - Mar 1 2016

Fingerprint

Arthritis
Non-Langerhans-Cell Histiocytosis
Skin Manifestations
Joint Diseases
Methotrexate
Autoimmune Diseases
Hand
Joints
Skin
Neoplasms
Therapeutics

Keywords

  • Dermatomyositis
  • Erosive polyarthropathy
  • Multicentric reticulohistiocytosis
  • Non-langerhans cell histiocytosis
  • Sjögren syndrome

ASJC Scopus subject areas

  • Dermatology

Cite this

Multicentric reticulohistiocytosis in a Taiwanese woman with Sjögren syndrome. / Cheng, Lan hsin; Chiang, Ying Yi.

In: Dermatologica Sinica, Vol. 34, No. 1, 01.03.2016, p. 42-45.

Research output: Contribution to journalArticle

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