Mucinous cystadenocarcinoma of the breast coexisting with infiltrating ductal carcinoma

Wei Yu Chen, Ching Shyang Chen, Hsin Chi Chen, Yi Ju Hung, Jan Show Chu

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A recently described and rare variant of breast carcinoma, mucinous cystadenocarcinoma (MCA), is reported in a 65-year-old post-menopausal woman. She presented with a gradually enlarged breast tumor. A well-circumscribed tumor measuring about 3 cm in diameter was noted in the mammographic and ultrasonographic examinations. The mammographic and ultrasonographic findings were indistinguishable from more common mucinous carcinoma (colloid carcinoma) of the breast. The gross appearance of the tumor was well-defined and cystic, consisting of abundant transparent to bloody mucin, as well as whitish solid parts. Microscopically, the tumor was characterized by abundant extracellular and intracellular mucin. It looked like a mucinous cystic neoplasm of the ovary and pancreas. Particularly, few microscopic foci of ordinary intermediate-grade infiltrating ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS) were observed around the main lesion in this case. A transition from ordinary DCIS to MCA in situ was found. It might indicate MCA derives from a metaplasia process of ordinary DCIS. MCA can be easily differentiated from mucinous carcinoma by quite different histologic and immunohistochemical findings. According to the previously reported and present cases, MCA of the breast more commonly affects elderly women and has a relatively favorable prognosis.

Original languageEnglish
Pages (from-to)781-786
Number of pages6
JournalPathology International
Volume54
Issue number10
DOIs
Publication statusPublished - Oct 2004

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Mucinous Cystadenocarcinoma
Ductal Carcinoma
Breast
Mucinous Adenocarcinoma
Carcinoma, Intraductal, Noninfiltrating
Mucins
Breast Neoplasms
Neoplasms
Metaplasia
Pancreatic Neoplasms
Ovarian Neoplasms

Keywords

  • Breast
  • Mucinous carcinoma
  • Mucinous cystadenocarcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Mucinous cystadenocarcinoma of the breast coexisting with infiltrating ductal carcinoma. / Chen, Wei Yu; Chen, Ching Shyang; Chen, Hsin Chi; Hung, Yi Ju; Chu, Jan Show.

In: Pathology International, Vol. 54, No. 10, 10.2004, p. 781-786.

Research output: Contribution to journalArticle

Chen, Wei Yu ; Chen, Ching Shyang ; Chen, Hsin Chi ; Hung, Yi Ju ; Chu, Jan Show. / Mucinous cystadenocarcinoma of the breast coexisting with infiltrating ductal carcinoma. In: Pathology International. 2004 ; Vol. 54, No. 10. pp. 781-786.
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