Mortality and Risk Factors in Psychiatric Inpatient with Dementia

A 13-year Long-Term Data Analysis

Ruey Chen, Wu-Chien Chien, Hsin Chu, Huei-Ling  Chiu, Chi Hsiang Chung, Chyn-Yng Yang, Nae-Fang Miao, Kuei-Ru Chou

Research output: Contribution to journalArticle

Abstract

Objective: The study aimed at identifying mortality and risk factors of psychiatric inpatients with dementia, a 13-year long-term data analysis. Method: This study adopted retrospective cohort design. The original claims data of 1 million randomly sampled beneficiaries between 1997 and 2010 from Taiwan’s National Health Insurance Research Database were analyzed. Mortality risk and risk factors were assessed using Cox regression analysis. Results: Among 320 dementia patients, a total of 83.4% had Alzheimer disease and 16.6% had vascular dementia. The mortality rates within 1 year after admission were reported for patients with vascular dementia (41.7%) and patients with Alzheimer disease (19.1%). A 1-year increase in age was associated with 3% increase in the risk of hospitalization mortality. Mortality risk among male inpatients was 2.9 times higher than that of female inpatients (P<0.001). The mortality risks among delirium inpatients, those with delusional symptoms, and those with depression had hazard ratios of 2.84 (P=0.004), 2.17 (P=0.008), and 1.82 (P=0.075) respectively, relative to inpatients with uncomplicated symptoms. Conclusion: The factors that influenced the mortality of dementia patients admitted to the psychiatric department were male sex, old age, delirium symptoms, and delusional symptoms.
Original languageEnglish
Pages (from-to)930-941
Number of pages12
JournalNeuropsychiatry
Volume8
Issue number3
Publication statusPublished - 2018

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Psychiatry
Dementia
Inpatients
Mortality
Vascular Dementia
Delirium
Alzheimer Disease
National Health Programs
Hospitalization
Retrospective Studies
Regression Analysis
Databases
Depression
Research

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Mortality and Risk Factors in Psychiatric Inpatient with Dementia : A 13-year Long-Term Data Analysis. / Chen, Ruey; Chien, Wu-Chien ; Chu, Hsin; Chiu, Huei-Ling ; Chung, Chi Hsiang; Yang, Chyn-Yng; Miao, Nae-Fang; Chou, Kuei-Ru.

In: Neuropsychiatry, Vol. 8, No. 3, 2018, p. 930-941.

Research output: Contribution to journalArticle

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author = "Ruey Chen and Wu-Chien Chien and Hsin Chu and Huei-Ling  Chiu and Chung, {Chi Hsiang} and Chyn-Yng Yang and Nae-Fang Miao and Kuei-Ru Chou",
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N2 - Objective: The study aimed at identifying mortality and risk factors of psychiatric inpatients with dementia, a 13-year long-term data analysis. Method: This study adopted retrospective cohort design. The original claims data of 1 million randomly sampled beneficiaries between 1997 and 2010 from Taiwan’s National Health Insurance Research Database were analyzed. Mortality risk and risk factors were assessed using Cox regression analysis. Results: Among 320 dementia patients, a total of 83.4% had Alzheimer disease and 16.6% had vascular dementia. The mortality rates within 1 year after admission were reported for patients with vascular dementia (41.7%) and patients with Alzheimer disease (19.1%). A 1-year increase in age was associated with 3% increase in the risk of hospitalization mortality. Mortality risk among male inpatients was 2.9 times higher than that of female inpatients (P<0.001). The mortality risks among delirium inpatients, those with delusional symptoms, and those with depression had hazard ratios of 2.84 (P=0.004), 2.17 (P=0.008), and 1.82 (P=0.075) respectively, relative to inpatients with uncomplicated symptoms. Conclusion: The factors that influenced the mortality of dementia patients admitted to the psychiatric department were male sex, old age, delirium symptoms, and delusional symptoms.

AB - Objective: The study aimed at identifying mortality and risk factors of psychiatric inpatients with dementia, a 13-year long-term data analysis. Method: This study adopted retrospective cohort design. The original claims data of 1 million randomly sampled beneficiaries between 1997 and 2010 from Taiwan’s National Health Insurance Research Database were analyzed. Mortality risk and risk factors were assessed using Cox regression analysis. Results: Among 320 dementia patients, a total of 83.4% had Alzheimer disease and 16.6% had vascular dementia. The mortality rates within 1 year after admission were reported for patients with vascular dementia (41.7%) and patients with Alzheimer disease (19.1%). A 1-year increase in age was associated with 3% increase in the risk of hospitalization mortality. Mortality risk among male inpatients was 2.9 times higher than that of female inpatients (P<0.001). The mortality risks among delirium inpatients, those with delusional symptoms, and those with depression had hazard ratios of 2.84 (P=0.004), 2.17 (P=0.008), and 1.82 (P=0.075) respectively, relative to inpatients with uncomplicated symptoms. Conclusion: The factors that influenced the mortality of dementia patients admitted to the psychiatric department were male sex, old age, delirium symptoms, and delusional symptoms.

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