Miscibility, mechanical characteristic and platelet adhesion of 6-O-carboxymethylchitosan/polyurethane semi-IPN membranes

Shu Huei Yu, Fwu Long Mi, Shin Shing Shyu, Chia Hun Tsai, Chih Kang Peng, Juin Yih Lai

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Novel semi-interpenetrating polymer network (semi-IPN) membranes were synthesized from 6-O-carboxymethylchitosan (6-OCC) and waterborne polyurethanes (WPU) with ester or ether soft segments. Results from the dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM) showed that miscibility and mechanical properties of the 6-OCC/WPU semi-IPNs were varied with their compositions and the cross-linking/grafting reactions. 6-OCC had better miscibility with the waterborne polyurethane containing ester soft segments, and could interfere the formation of hydrogen bonds between the ester soft segments and the NH groups in hard-segments. The 6-OCC/WPU composite membranes demonstrated microphase-separated structures in which the 6-OCC particles were dispersed in the matrix of the WPU-rich phase. The 6-OCC/WPU composites were cross-linked with glutaraldehyde or cross-linked/grafted with ethylene glycol diglycidyl ether (EGDE) to form 6-OCC/WPU semi-IPN membranes. Generally speaking, cross-linking and grafting altered the miscibility of the 6-OCC/WPU semi-IPN membranes, resulted in their different tensile strength and modulus. The growth of a model bacterial - Escherichia coli and the adhesion of platelets on the surfaces of the 6-OCC/WPU semi-IPN membranes indicated that the antibacterial ability and blood compatibility of WPU membranes were improved by the addition of 6-OCC, and strongly related to their cross-linking/grafting network structures. It was concluded that the 6-OCC/WPU semi-IPN membranes could be good candidates for biomedical applications.

Original languageEnglish
Pages (from-to)68-80
Number of pages13
JournalJournal of Membrane Science
Volume276
Issue number1-2
DOIs
Publication statusPublished - May 1 2006
Externally publishedYes

Fingerprint

Interpenetrating polymer networks
Polyurethanes
Platelets
platelets
Polymers
adhesion
Blood Platelets
Adhesion
solubility
Solubility
membranes
Membranes
polymers
esters
ethers
Esters
composite materials
Ethers
Escherichia
O-carboxymethylchitosan

Keywords

  • Chitosan
  • Semi-interpenetrating polymer networks
  • Waterborne polyurethane

ASJC Scopus subject areas

  • Filtration and Separation
  • Polymers and Plastics

Cite this

Miscibility, mechanical characteristic and platelet adhesion of 6-O-carboxymethylchitosan/polyurethane semi-IPN membranes. / Yu, Shu Huei; Mi, Fwu Long; Shyu, Shin Shing; Tsai, Chia Hun; Peng, Chih Kang; Lai, Juin Yih.

In: Journal of Membrane Science, Vol. 276, No. 1-2, 01.05.2006, p. 68-80.

Research output: Contribution to journalArticle

Yu, Shu Huei ; Mi, Fwu Long ; Shyu, Shin Shing ; Tsai, Chia Hun ; Peng, Chih Kang ; Lai, Juin Yih. / Miscibility, mechanical characteristic and platelet adhesion of 6-O-carboxymethylchitosan/polyurethane semi-IPN membranes. In: Journal of Membrane Science. 2006 ; Vol. 276, No. 1-2. pp. 68-80.
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AU - Tsai, Chia Hun

AU - Peng, Chih Kang

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AB - Novel semi-interpenetrating polymer network (semi-IPN) membranes were synthesized from 6-O-carboxymethylchitosan (6-OCC) and waterborne polyurethanes (WPU) with ester or ether soft segments. Results from the dynamic mechanical analysis (DMA) and scanning electron microscopy (SEM) showed that miscibility and mechanical properties of the 6-OCC/WPU semi-IPNs were varied with their compositions and the cross-linking/grafting reactions. 6-OCC had better miscibility with the waterborne polyurethane containing ester soft segments, and could interfere the formation of hydrogen bonds between the ester soft segments and the NH groups in hard-segments. The 6-OCC/WPU composite membranes demonstrated microphase-separated structures in which the 6-OCC particles were dispersed in the matrix of the WPU-rich phase. The 6-OCC/WPU composites were cross-linked with glutaraldehyde or cross-linked/grafted with ethylene glycol diglycidyl ether (EGDE) to form 6-OCC/WPU semi-IPN membranes. Generally speaking, cross-linking and grafting altered the miscibility of the 6-OCC/WPU semi-IPN membranes, resulted in their different tensile strength and modulus. The growth of a model bacterial - Escherichia coli and the adhesion of platelets on the surfaces of the 6-OCC/WPU semi-IPN membranes indicated that the antibacterial ability and blood compatibility of WPU membranes were improved by the addition of 6-OCC, and strongly related to their cross-linking/grafting network structures. It was concluded that the 6-OCC/WPU semi-IPN membranes could be good candidates for biomedical applications.

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