Migraine and erectile dysfunction: Evidence from a population-based case-control study

Chao Yuan Huang, Joseph J. Keller, Jau Jiuan Sheu, Herng Ching Lin

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Background: This case-control study aimed to estimate the association between erectile dysfunction (ED) and migraines using a nationwide population-based database in Taiwan.Methods: The data used for this matched case-control study were retrieved from the Taiwan Longitudinal Health Insurance Database 2000. We identified 5763 patients with ED as the cases and randomly selected 17,289 patients as the controls. Conditional logistic regression was used to calculate the odds ratios (OR) for prior migraine between cases and controls.Results: After adjusting for hypertension, diabetes, hyperlipidaemia, renal disease, coronary heart disease, obesity, and alcohol abuse/alcohol dependence syndrome, conditional logistic regression revealed that among ED patients the odds of having been previously diagnosed with migraines was 1.63 (95% CI, 1.39-1.91) that of the control group. This risk was more pronounced in younger groups, with the highest risk being detected among those aged between 30 and 39 years. After adjusting for the above mentioned comorbidities, ED patients aged between 30 and 39 years were found to be at 1.98 (95% CI, 1.67-2.23) times the risk of controls for having been previously diagnosed with migraines.Conclusion: We conclude that ED is associated with having been previously diagnosed with migraines, particularly in younger populations.

Original languageEnglish
Pages (from-to)366-372
Number of pages7
JournalCephalalgia
Volume32
Issue number5
DOIs
Publication statusPublished - Apr 2012

Keywords

  • Migraine
  • epidemiology
  • erectile dysfunction

ASJC Scopus subject areas

  • Clinical Neurology

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