Microbiologic and histologic diagnosis of histoplasmosis in Taiwan

Tze Wah Kao, Chien Ching Hung, Po Ren Hsueh, Tzou Yien Lin, Mao Yuan Chen, Kwen Tay Luh, Chi Yen Chuang

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Histoplasmosis is one of the most common opportunistic fungal infections in immunocompromoised patients in endemic areas. We report the first two microbiologically documented cases of histoplasmosis in Taiwan. The first patient, with acquired immunodeficiency syndrome and a depleted CD4+ lymphocyte count, presented with a history of prolonged fever, papular skin rashes, pancytopenia and elevation of liver enzymes. He was diagnosed and treated initially for systematic toxoplasmosis, but the microbiologic and pathologic findings of the autopsied specimens disclosed disseminated infection caused by Histoplasma capsulatum. The second patient, an elderly man receiving corticosteroids for adrenal insufficiency, manifested with laryngeal histoplasmosis and was successfully treated with ketoconazole.

Original languageEnglish
Pages (from-to)374-378
Number of pages5
JournalJournal of the Formosan Medical Association
Volume96
Issue number5
Publication statusPublished - May 1997
Externally publishedYes

Fingerprint

Histoplasmosis
Taiwan
Histoplasma
Adrenal Insufficiency
Pancytopenia
Ketoconazole
Mycoses
Toxoplasmosis
Opportunistic Infections
CD4 Lymphocyte Count
Exanthema
Adrenal Cortex Hormones
Acquired Immunodeficiency Syndrome
Fever
Liver
Enzymes
Infection

Keywords

  • AIDS
  • Disseminated histoplasmosis
  • Histoplasma capsulatum
  • Laryngeal histoplasmosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kao, T. W., Hung, C. C., Hsueh, P. R., Lin, T. Y., Chen, M. Y., Luh, K. T., & Chuang, C. Y. (1997). Microbiologic and histologic diagnosis of histoplasmosis in Taiwan. Journal of the Formosan Medical Association, 96(5), 374-378.

Microbiologic and histologic diagnosis of histoplasmosis in Taiwan. / Kao, Tze Wah; Hung, Chien Ching; Hsueh, Po Ren; Lin, Tzou Yien; Chen, Mao Yuan; Luh, Kwen Tay; Chuang, Chi Yen.

In: Journal of the Formosan Medical Association, Vol. 96, No. 5, 05.1997, p. 374-378.

Research output: Contribution to journalArticle

Kao, TW, Hung, CC, Hsueh, PR, Lin, TY, Chen, MY, Luh, KT & Chuang, CY 1997, 'Microbiologic and histologic diagnosis of histoplasmosis in Taiwan', Journal of the Formosan Medical Association, vol. 96, no. 5, pp. 374-378.
Kao, Tze Wah ; Hung, Chien Ching ; Hsueh, Po Ren ; Lin, Tzou Yien ; Chen, Mao Yuan ; Luh, Kwen Tay ; Chuang, Chi Yen. / Microbiologic and histologic diagnosis of histoplasmosis in Taiwan. In: Journal of the Formosan Medical Association. 1997 ; Vol. 96, No. 5. pp. 374-378.
@article{82484ad32bfa46dea66a838a0742cce1,
title = "Microbiologic and histologic diagnosis of histoplasmosis in Taiwan",
abstract = "Histoplasmosis is one of the most common opportunistic fungal infections in immunocompromoised patients in endemic areas. We report the first two microbiologically documented cases of histoplasmosis in Taiwan. The first patient, with acquired immunodeficiency syndrome and a depleted CD4+ lymphocyte count, presented with a history of prolonged fever, papular skin rashes, pancytopenia and elevation of liver enzymes. He was diagnosed and treated initially for systematic toxoplasmosis, but the microbiologic and pathologic findings of the autopsied specimens disclosed disseminated infection caused by Histoplasma capsulatum. The second patient, an elderly man receiving corticosteroids for adrenal insufficiency, manifested with laryngeal histoplasmosis and was successfully treated with ketoconazole.",
keywords = "AIDS, Disseminated histoplasmosis, Histoplasma capsulatum, Laryngeal histoplasmosis",
author = "Kao, {Tze Wah} and Hung, {Chien Ching} and Hsueh, {Po Ren} and Lin, {Tzou Yien} and Chen, {Mao Yuan} and Luh, {Kwen Tay} and Chuang, {Chi Yen}",
year = "1997",
month = "5",
language = "English",
volume = "96",
pages = "374--378",
journal = "Journal of the Formosan Medical Association",
issn = "0929-6646",
publisher = "Elsevier Science Publishers B.V.",
number = "5",

}

TY - JOUR

T1 - Microbiologic and histologic diagnosis of histoplasmosis in Taiwan

AU - Kao, Tze Wah

AU - Hung, Chien Ching

AU - Hsueh, Po Ren

AU - Lin, Tzou Yien

AU - Chen, Mao Yuan

AU - Luh, Kwen Tay

AU - Chuang, Chi Yen

PY - 1997/5

Y1 - 1997/5

N2 - Histoplasmosis is one of the most common opportunistic fungal infections in immunocompromoised patients in endemic areas. We report the first two microbiologically documented cases of histoplasmosis in Taiwan. The first patient, with acquired immunodeficiency syndrome and a depleted CD4+ lymphocyte count, presented with a history of prolonged fever, papular skin rashes, pancytopenia and elevation of liver enzymes. He was diagnosed and treated initially for systematic toxoplasmosis, but the microbiologic and pathologic findings of the autopsied specimens disclosed disseminated infection caused by Histoplasma capsulatum. The second patient, an elderly man receiving corticosteroids for adrenal insufficiency, manifested with laryngeal histoplasmosis and was successfully treated with ketoconazole.

AB - Histoplasmosis is one of the most common opportunistic fungal infections in immunocompromoised patients in endemic areas. We report the first two microbiologically documented cases of histoplasmosis in Taiwan. The first patient, with acquired immunodeficiency syndrome and a depleted CD4+ lymphocyte count, presented with a history of prolonged fever, papular skin rashes, pancytopenia and elevation of liver enzymes. He was diagnosed and treated initially for systematic toxoplasmosis, but the microbiologic and pathologic findings of the autopsied specimens disclosed disseminated infection caused by Histoplasma capsulatum. The second patient, an elderly man receiving corticosteroids for adrenal insufficiency, manifested with laryngeal histoplasmosis and was successfully treated with ketoconazole.

KW - AIDS

KW - Disseminated histoplasmosis

KW - Histoplasma capsulatum

KW - Laryngeal histoplasmosis

UR - http://www.scopus.com/inward/record.url?scp=0030956364&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030956364&partnerID=8YFLogxK

M3 - Article

VL - 96

SP - 374

EP - 378

JO - Journal of the Formosan Medical Association

JF - Journal of the Formosan Medical Association

SN - 0929-6646

IS - 5

ER -