Methylpiperidinopyrazole attenuates estrogen-induced mitochondrial energy production and subsequent osteoblast maturation via an estrogen receptor alpha-dependent mechanism

Physics & Astronomy

• estrogens 100%
• osteoblasts 83%
• energy 17%
• oxidase 16%
• bones 11%
• adenosine triphosphate 9%
• collagens 8%
• pretreatment 8%
• rats 8%
• proteins 6%
• ribonucleic acids 6%
• osteogenesis 6%
• adenosines 6%
• osteoporosis 5%
• cytochromes 5%
• mitochondria 5%
• cytoplasm 4%
• progressions 4%
• enzymes 4%
• phosphates 3%
• induction 3%
• activation 3%
• synthesis 2%
• causes 2%
• augmentation 2%
• cells 2%

Medicine & Life Sciences

• Estrogen Receptor alpha 69%
• Osteoblasts 56%
• Estrogens 48%
• Estrogen Receptors 22%
• Bone Morphogenetic Protein 6 19%
• Collagen Type I 11%
• Oxidoreductases 10%
• Messenger RNA 10%
• mitochondrial messenger RNA 9%
• Adenosine Triphosphate 9%
• Adenine Nucleotides 7%
• Postmenopausal Osteoporosis 7%
• Electron Transport Complex IV 6%
• Bone Remodeling 6%
• Skull 5%
• Energy Metabolism 5%
• Osteogenesis 5%
• Mitochondria 4%
• Cytoplasm 4%
• Survival 3%
• Enzymes 3%
• Therapeutics 0%

Chemical Compounds

• Estrogen 63%
• Energy 27%
• Collagen 16%
• Adenosine Phosphate 14%
• Estradiol 9%
• Antagonist 7%
• Cytochrome 7%