Methodologic advances in the cytogenetic analysis of human solid tumors

Jeffrey Trent; Kent Crickard; Zenon Gibas; Angela Goodacre; Sen Pathak; Avery A. Sandberg; Floyd Thompson; Jacqueline Whang-Peng; Sandra Wolman

doi:10.1016/0165-4608(86)90372-9

Methodologic advances in the cytogenetic analysis of human solid tumors

Jeffrey Trent, Kent Crickard, Zenon Gibas, Angela Goodacre, Sen Pathak, Avery A. Sandberg, Floyd Thompson, Jacqueline Whang-Peng, Sandra Wolman

Research output: Contribution to journal › Article

43 Citations (Scopus)

Abstract

The major obstacle to successful cytogenetic analysis of human solid tumors is the acquisition of sufficient numbers of good quality metaphases for detailed cytogenetic analysis. At present, no single methodologic approach has been proven to provide successful chromosomal analysis of all human solid tumors. The technical aspects of cell culture, chromosome harvesting, and chromosome banding were the focus of considerable discussion during the First Workshop on Chromosomes in Solid Tumors. This report provides summaries of several technical protocols, emanating from several different laboratories, which have contributed to successful chromosome analysis of a variety of human solid tumors.

Original language	English
Pages (from-to)	57-66
Number of pages	10
Journal	Cancer Genetics and Cytogenetics
Volume	19
Issue number	1-2
DOIs	https://doi.org/10.1016/0165-4608(86)90372-9
Publication status	Published - Jan 1 1986
Externally published	Yes

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ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

Cite this

Trent, J., Crickard, K., Gibas, Z., Goodacre, A., Pathak, S., Sandberg, A. A., Thompson, F., Whang-Peng, J., & Wolman, S. (1986). Methodologic advances in the cytogenetic analysis of human solid tumors. Cancer Genetics and Cytogenetics, 19(1-2), 57-66. https://doi.org/10.1016/0165-4608(86)90372-9

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10.1016/0165-4608(86)90372-9