Abstract
The major obstacle to successful cytogenetic analysis of human solid tumors is the acquisition of sufficient numbers of good quality metaphases for detailed cytogenetic analysis. At present, no single methodologic approach has been proven to provide successful chromosomal analysis of all human solid tumors. The technical aspects of cell culture, chromosome harvesting, and chromosome banding were the focus of considerable discussion during the First Workshop on Chromosomes in Solid Tumors. This report provides summaries of several technical protocols, emanating from several different laboratories, which have contributed to successful chromosome analysis of a variety of human solid tumors.
| Original language | English |
|---|---|
| Pages (from-to) | 57-66 |
| Number of pages | 10 |
| Journal | Cancer Genetics and Cytogenetics |
| Volume | 19 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Jan 1 1986 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research
Cite this
Methodologic advances in the cytogenetic analysis of human solid tumors. / Trent, Jeffrey; Crickard, Kent; Gibas, Zenon; Goodacre, Angela; Pathak, Sen; Sandberg, Avery A.; Thompson, Floyd; Whang-Peng, Jacqueline; Wolman, Sandra.
In: Cancer Genetics and Cytogenetics, Vol. 19, No. 1-2, 01.01.1986, p. 57-66.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Methodologic advances in the cytogenetic analysis of human solid tumors
AU - Trent, Jeffrey
AU - Crickard, Kent
AU - Gibas, Zenon
AU - Goodacre, Angela
AU - Pathak, Sen
AU - Sandberg, Avery A.
AU - Thompson, Floyd
AU - Whang-Peng, Jacqueline
AU - Wolman, Sandra
PY - 1986/1/1
Y1 - 1986/1/1
N2 - The major obstacle to successful cytogenetic analysis of human solid tumors is the acquisition of sufficient numbers of good quality metaphases for detailed cytogenetic analysis. At present, no single methodologic approach has been proven to provide successful chromosomal analysis of all human solid tumors. The technical aspects of cell culture, chromosome harvesting, and chromosome banding were the focus of considerable discussion during the First Workshop on Chromosomes in Solid Tumors. This report provides summaries of several technical protocols, emanating from several different laboratories, which have contributed to successful chromosome analysis of a variety of human solid tumors.
AB - The major obstacle to successful cytogenetic analysis of human solid tumors is the acquisition of sufficient numbers of good quality metaphases for detailed cytogenetic analysis. At present, no single methodologic approach has been proven to provide successful chromosomal analysis of all human solid tumors. The technical aspects of cell culture, chromosome harvesting, and chromosome banding were the focus of considerable discussion during the First Workshop on Chromosomes in Solid Tumors. This report provides summaries of several technical protocols, emanating from several different laboratories, which have contributed to successful chromosome analysis of a variety of human solid tumors.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022573471&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(86)90372-9
DO - 10.1016/0165-4608(86)90372-9
M3 - Article
C2 - 3940180
AN - SCOPUS:0022573471
VL - 19
SP - 57
EP - 66
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 1-2
ER -