Methodologic advances in the cytogenetic analysis of human solid tumors

Jeffrey Trent, Kent Crickard, Zenon Gibas, Angela Goodacre, Sen Pathak, Avery A. Sandberg, Floyd Thompson, Jacqueline Whang-Peng, Sandra Wolman

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

The major obstacle to successful cytogenetic analysis of human solid tumors is the acquisition of sufficient numbers of good quality metaphases for detailed cytogenetic analysis. At present, no single methodologic approach has been proven to provide successful chromosomal analysis of all human solid tumors. The technical aspects of cell culture, chromosome harvesting, and chromosome banding were the focus of considerable discussion during the First Workshop on Chromosomes in Solid Tumors. This report provides summaries of several technical protocols, emanating from several different laboratories, which have contributed to successful chromosome analysis of a variety of human solid tumors.

Original languageEnglish
Pages (from-to)57-66
Number of pages10
JournalCancer Genetics and Cytogenetics
Volume19
Issue number1-2
DOIs
Publication statusPublished - Jan 1 1986
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

Cite this

Trent, J., Crickard, K., Gibas, Z., Goodacre, A., Pathak, S., Sandberg, A. A., Thompson, F., Whang-Peng, J., & Wolman, S. (1986). Methodologic advances in the cytogenetic analysis of human solid tumors. Cancer Genetics and Cytogenetics, 19(1-2), 57-66. https://doi.org/10.1016/0165-4608(86)90372-9