Metastatic choroidal tumors in Taiwan: An 11-year experience

Tsung Jen Wang, Chung May Yang, Tzyy Chang Ho, Jen Shang Huang, Chang Pin Lin, Chang Hao Yang, Muh Shy Chen, Luke Long Kuang Lin

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20 Citations (Scopus)

Abstract

PURPOSE: To report the clinical features, the primary sites, and overall prognosis of choroidal metastasis. DESIGN: Observational case series. METHODS: Included were all cases of choroidal metastases evaluated at National Taiwan University Hospital over an 11-year period. Patients with blood or lymphoproliferative diseases were excluded. Clinical features were correlated with disease entity and prognosis. RESULTS: A total of 36 patients with choroidal metastases were identified. The mean age was 53.9 ± 12.8 years. The mean follow-up period was 5.1 ± 4.2 months. The primary sites of tumors were lung in 18 (50%), breast in eight (22.2%), gastrointestinal tract in three (8.3%), pancreas in two (5.6%), ovary in two (5.6%), kidney in one (2.8%), liver in one (2.8%), and unknown in one (2.8%). Twenty-two patients (61%) died during follow-up. Mean life span after diagnosis was 4.3 months in these 22 patients. CONCLUSIONS: Lung and breast cancers represent more than two thirds of primary tumor sites. Choroidal metastases may indicate terminal status of the underlying malignancy and short survival time.

Original languageEnglish
Pages (from-to)735-737
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume140
Issue number4
DOIs
Publication statusPublished - Oct 2005
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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    Wang, T. J., Yang, C. M., Ho, T. C., Huang, J. S., Lin, C. P., Yang, C. H., Chen, M. S., & Lin, L. L. K. (2005). Metastatic choroidal tumors in Taiwan: An 11-year experience. American Journal of Ophthalmology, 140(4), 735-737. https://doi.org/10.1016/j.ajo.2005.03.068