Mercury concentration in meconium and risk assessment of fish consumption among pregnant women in Taiwan

Chuen Bin Jiang, Ching-Ying Yeh, Hung Chang Lee, Ming Jun Chen, Fang Yu Hung, Sheng Shiung Fang, Ling Chu Chien

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Meconium is a matrix that can be obtained easily and noninvasively and is useful for detecting antenatal fetal exposure to environmental toxins. Taiwan is an island with high fish consumption, and many pregnant women would like to enjoy the benefits of fish without jeopardizing their health or that of their child. The aim of this study is to assess the mercury concentration in meconium in relation to the health risk of mercury exposure. A total of 198 mother-infant pairs residing in the city of HsinChu were recruited for the study between January 2007 and June 2007. The average mean concentration of mercury in meconium was 79.2 ± 7.3 ng g- 1 dry wt We use the Monte Carlo technique to assess the uncertainty in risk assessment and the impact of these uncertainties on the estimation of expected risk of mercury intake from fish in mothers. Based on the FAO/WHO's tolerable daily intake of methylmercury (0.23 μg kg- 1 d- 1), we found that 17.3% and 14.0% of the daily mercury exposure estimated exceeded the reference dose for foreign-born and Taiwan-born mothers, respectively. We found that the mercury concentration in meconium was much higher than in other studies, except for one study done in Tagum in the Philippines where mercury is used in gold mining. This may be because Asia is the largest emitter of anthropogenic mercury, accounting for 53% of worldwide emissions. Sensitivity analysis suggests that mercury concentration in fish and the rate of ingesting fish may be the key parameters for governments offering risk management guidance to protect the health of mothers and unborn babies.

Original languageEnglish
Pages (from-to)518-523
Number of pages6
JournalScience of the Total Environment
Volume408
Issue number3
DOIs
Publication statusPublished - Jan 1 2010

Fingerprint

Mercury
Risk assessment
Fish
risk assessment
fish
Health
Gold mines
Health risks
Risk management
Sensitivity analysis
woman
mercury
consumption
Food and Agricultural Organization
methylmercury
health risk
toxin
sensitivity analysis
gold
matrix

Keywords

  • Daily mercury exposure
  • Meconium
  • Mercury concentration in fish
  • Monte Carlo simulation

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Waste Management and Disposal
  • Environmental Engineering

Cite this

Mercury concentration in meconium and risk assessment of fish consumption among pregnant women in Taiwan. / Jiang, Chuen Bin; Yeh, Ching-Ying; Lee, Hung Chang; Chen, Ming Jun; Hung, Fang Yu; Fang, Sheng Shiung; Chien, Ling Chu.

In: Science of the Total Environment, Vol. 408, No. 3, 01.01.2010, p. 518-523.

Research output: Contribution to journalArticle

Jiang, Chuen Bin ; Yeh, Ching-Ying ; Lee, Hung Chang ; Chen, Ming Jun ; Hung, Fang Yu ; Fang, Sheng Shiung ; Chien, Ling Chu. / Mercury concentration in meconium and risk assessment of fish consumption among pregnant women in Taiwan. In: Science of the Total Environment. 2010 ; Vol. 408, No. 3. pp. 518-523.
@article{9e262f773ece43ddb00caf5886f5bcb7,
title = "Mercury concentration in meconium and risk assessment of fish consumption among pregnant women in Taiwan",
abstract = "Meconium is a matrix that can be obtained easily and noninvasively and is useful for detecting antenatal fetal exposure to environmental toxins. Taiwan is an island with high fish consumption, and many pregnant women would like to enjoy the benefits of fish without jeopardizing their health or that of their child. The aim of this study is to assess the mercury concentration in meconium in relation to the health risk of mercury exposure. A total of 198 mother-infant pairs residing in the city of HsinChu were recruited for the study between January 2007 and June 2007. The average mean concentration of mercury in meconium was 79.2 ± 7.3 ng g- 1 dry wt We use the Monte Carlo technique to assess the uncertainty in risk assessment and the impact of these uncertainties on the estimation of expected risk of mercury intake from fish in mothers. Based on the FAO/WHO's tolerable daily intake of methylmercury (0.23 μg kg- 1 d- 1), we found that 17.3{\%} and 14.0{\%} of the daily mercury exposure estimated exceeded the reference dose for foreign-born and Taiwan-born mothers, respectively. We found that the mercury concentration in meconium was much higher than in other studies, except for one study done in Tagum in the Philippines where mercury is used in gold mining. This may be because Asia is the largest emitter of anthropogenic mercury, accounting for 53{\%} of worldwide emissions. Sensitivity analysis suggests that mercury concentration in fish and the rate of ingesting fish may be the key parameters for governments offering risk management guidance to protect the health of mothers and unborn babies.",
keywords = "Daily mercury exposure, Meconium, Mercury concentration in fish, Monte Carlo simulation",
author = "Jiang, {Chuen Bin} and Ching-Ying Yeh and Lee, {Hung Chang} and Chen, {Ming Jun} and Hung, {Fang Yu} and Fang, {Sheng Shiung} and Chien, {Ling Chu}",
year = "2010",
month = "1",
day = "1",
doi = "10.1016/j.scitotenv.2009.10.043",
language = "English",
volume = "408",
pages = "518--523",
journal = "Science of the Total Environment",
issn = "0048-9697",
publisher = "Elsevier",
number = "3",

}

TY - JOUR

T1 - Mercury concentration in meconium and risk assessment of fish consumption among pregnant women in Taiwan

AU - Jiang, Chuen Bin

AU - Yeh, Ching-Ying

AU - Lee, Hung Chang

AU - Chen, Ming Jun

AU - Hung, Fang Yu

AU - Fang, Sheng Shiung

AU - Chien, Ling Chu

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Meconium is a matrix that can be obtained easily and noninvasively and is useful for detecting antenatal fetal exposure to environmental toxins. Taiwan is an island with high fish consumption, and many pregnant women would like to enjoy the benefits of fish without jeopardizing their health or that of their child. The aim of this study is to assess the mercury concentration in meconium in relation to the health risk of mercury exposure. A total of 198 mother-infant pairs residing in the city of HsinChu were recruited for the study between January 2007 and June 2007. The average mean concentration of mercury in meconium was 79.2 ± 7.3 ng g- 1 dry wt We use the Monte Carlo technique to assess the uncertainty in risk assessment and the impact of these uncertainties on the estimation of expected risk of mercury intake from fish in mothers. Based on the FAO/WHO's tolerable daily intake of methylmercury (0.23 μg kg- 1 d- 1), we found that 17.3% and 14.0% of the daily mercury exposure estimated exceeded the reference dose for foreign-born and Taiwan-born mothers, respectively. We found that the mercury concentration in meconium was much higher than in other studies, except for one study done in Tagum in the Philippines where mercury is used in gold mining. This may be because Asia is the largest emitter of anthropogenic mercury, accounting for 53% of worldwide emissions. Sensitivity analysis suggests that mercury concentration in fish and the rate of ingesting fish may be the key parameters for governments offering risk management guidance to protect the health of mothers and unborn babies.

AB - Meconium is a matrix that can be obtained easily and noninvasively and is useful for detecting antenatal fetal exposure to environmental toxins. Taiwan is an island with high fish consumption, and many pregnant women would like to enjoy the benefits of fish without jeopardizing their health or that of their child. The aim of this study is to assess the mercury concentration in meconium in relation to the health risk of mercury exposure. A total of 198 mother-infant pairs residing in the city of HsinChu were recruited for the study between January 2007 and June 2007. The average mean concentration of mercury in meconium was 79.2 ± 7.3 ng g- 1 dry wt We use the Monte Carlo technique to assess the uncertainty in risk assessment and the impact of these uncertainties on the estimation of expected risk of mercury intake from fish in mothers. Based on the FAO/WHO's tolerable daily intake of methylmercury (0.23 μg kg- 1 d- 1), we found that 17.3% and 14.0% of the daily mercury exposure estimated exceeded the reference dose for foreign-born and Taiwan-born mothers, respectively. We found that the mercury concentration in meconium was much higher than in other studies, except for one study done in Tagum in the Philippines where mercury is used in gold mining. This may be because Asia is the largest emitter of anthropogenic mercury, accounting for 53% of worldwide emissions. Sensitivity analysis suggests that mercury concentration in fish and the rate of ingesting fish may be the key parameters for governments offering risk management guidance to protect the health of mothers and unborn babies.

KW - Daily mercury exposure

KW - Meconium

KW - Mercury concentration in fish

KW - Monte Carlo simulation

UR - http://www.scopus.com/inward/record.url?scp=70649086091&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70649086091&partnerID=8YFLogxK

U2 - 10.1016/j.scitotenv.2009.10.043

DO - 10.1016/j.scitotenv.2009.10.043

M3 - Article

VL - 408

SP - 518

EP - 523

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

IS - 3

ER -