Abstract
Background and Aim: In Taiwan, unsedated esophagogastroduodenoscopy (EGD) is widely used, but it is uncomfortable for some patients. While meperidine has been adopted in colonoscopy, its use in EGD has not received extensive attention. This was a prospective study to investigate the use of meperidine as a single sedative agent during EGD. Methods: One hundred and forty patients were randomized to receive either 25-mg meperidine (n=70) or placebo (n=70) by intramuscular injection before EGD. The primary outcome was patient discomfort scores. The secondary outcomes included patient, endoscopist, and EGD-related variables. Results: Patients in the meperidine group reported less discomfort during esophageal intubation (median score of 2.0 and interquartile range [IQR] of 0-4.0 vs median score of 4.8 and IQR of 1.7-7.0, respectively; P
| Original language | English |
|---|---|
| Pages (from-to) | 1167-1173 |
| Number of pages | 7 |
| Journal | Journal of Gastroenterology and Hepatology (Australia) |
| Volume | 28 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2013 |
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Keywords
- Esophagogastroduodenoscopy
- Meperidine
- Minimal sedation
ASJC Scopus subject areas
- Gastroenterology
- Hepatology
Cite this
Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double-blind, randomized, controlled study. / Hsieh, Yu Hsi; Lin, Hwai Jeng; Hsieh, Jin Jian; Tseng, Kuo Chih; Tseng, Chih Wei; Hung, Tsung Hsing; Leung, Felix W.
In: Journal of Gastroenterology and Hepatology (Australia), Vol. 28, No. 7, 2013, p. 1167-1173.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Meperidine as the single sedative agent during esophagogastroduodenoscopy, a double-blind, randomized, controlled study
AU - Hsieh, Yu Hsi
AU - Lin, Hwai Jeng
AU - Hsieh, Jin Jian
AU - Tseng, Kuo Chih
AU - Tseng, Chih Wei
AU - Hung, Tsung Hsing
AU - Leung, Felix W.
PY - 2013
Y1 - 2013
N2 - Background and Aim: In Taiwan, unsedated esophagogastroduodenoscopy (EGD) is widely used, but it is uncomfortable for some patients. While meperidine has been adopted in colonoscopy, its use in EGD has not received extensive attention. This was a prospective study to investigate the use of meperidine as a single sedative agent during EGD. Methods: One hundred and forty patients were randomized to receive either 25-mg meperidine (n=70) or placebo (n=70) by intramuscular injection before EGD. The primary outcome was patient discomfort scores. The secondary outcomes included patient, endoscopist, and EGD-related variables. Results: Patients in the meperidine group reported less discomfort during esophageal intubation (median score of 2.0 and interquartile range [IQR] of 0-4.0 vs median score of 4.8 and IQR of 1.7-7.0, respectively; P
AB - Background and Aim: In Taiwan, unsedated esophagogastroduodenoscopy (EGD) is widely used, but it is uncomfortable for some patients. While meperidine has been adopted in colonoscopy, its use in EGD has not received extensive attention. This was a prospective study to investigate the use of meperidine as a single sedative agent during EGD. Methods: One hundred and forty patients were randomized to receive either 25-mg meperidine (n=70) or placebo (n=70) by intramuscular injection before EGD. The primary outcome was patient discomfort scores. The secondary outcomes included patient, endoscopist, and EGD-related variables. Results: Patients in the meperidine group reported less discomfort during esophageal intubation (median score of 2.0 and interquartile range [IQR] of 0-4.0 vs median score of 4.8 and IQR of 1.7-7.0, respectively; P
KW - Esophagogastroduodenoscopy
KW - Meperidine
KW - Minimal sedation
UR - http://www.scopus.com/inward/record.url?scp=84879428314&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84879428314&partnerID=8YFLogxK
U2 - 10.1111/jgh.12183
DO - 10.1111/jgh.12183
M3 - Article
C2 - 23431993
AN - SCOPUS:84879428314
VL - 28
SP - 1167
EP - 1173
JO - Journal of Gastroenterology and Hepatology (Australia)
JF - Journal of Gastroenterology and Hepatology (Australia)
SN - 0815-9319
IS - 7
ER -