Medullary Vein Blockage Sign Detected by Susceptibility-Weighted Imaging for Diagnosing Metastatic Brain Tumors

Research output: Contribution to conferencePaper

Abstract

Purpose: The aim of this study was to identify an anatomical relationship between deep medullary vein and these three
common brain tumors, which may improve preoperative diagnostic accuracy.
Materials and Methods: Patients with SWI studies of the brain and pathology-confirmed PCNSL, high-grade glioma,
or intraaxial metastatic lesions between 2009 and 2015 were reviewed. On SWI, those whose deep medullary veins
could be visualized within 5-mm range of the enhancing tumor were enrolled into the study. A total of 27 patients were
recruited and images were reviewed for signs of medullary vein blockage (MVB). MVB was defined as a deep
medullary vein terminating at the margin of the tumor. The sensitivity, specificity, and diagnostic accuracy of MVB in
differentiating PCNSL, high-grade glioma, and metastasis were analyzed.
Results: A total of 11 PCNSL, 5 high-grade gliomas, and 11 metastatic cases were reviewed. MVB was not identified
in any of imaging studies for PCNSL or high-grade glioma patients. However, MVB was noted in 9 of 11 metastatic
tumors (81.8%). The MVB sign showed a diagnostic specificity and accuracy of 100% and 92.6%, respectively, for
intraaxial metastatic tumors.
Conclusion: The MVB sign on SWI images has a high accuracy and specificity for differentiating metastatic brain
tumors from PCNSL, high-grade gliomas and thus may aid physicians in treatment planning.
Original languageEnglish
Publication statusPublished - Mar 2017
EventThe 66th Annual Meeting of RSROC - NTUH International Convention Center, Taipei, Taiwan
Duration: Mar 18 2017Mar 19 2017
https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=93

Conference

ConferenceThe 66th Annual Meeting of RSROC
CountryTaiwan
CityTaipei
Period3/18/173/19/17
Internet address

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Brain Neoplasms
Veins
Glioma
Neoplasms
Pathology
Neoplasm Metastasis
Physicians
Sensitivity and Specificity
Brain

Cite this

Medullary Vein Blockage Sign Detected by Susceptibility-Weighted Imaging for Diagnosing Metastatic Brain Tumors. / Yang, Shih-Hung; Hong, Chien-Tai; Chen, Chia-Yuen; Chen, Wei-Yu; Tsai, Fong Y.; Chan, Wing P.

2017. Paper presented at The 66th Annual Meeting of RSROC, Taipei, Taiwan.

Research output: Contribution to conferencePaper

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title = "Medullary Vein Blockage Sign Detected by Susceptibility-Weighted Imaging for Diagnosing Metastatic Brain Tumors",
abstract = "Purpose: The aim of this study was to identify an anatomical relationship between deep medullary vein and these threecommon brain tumors, which may improve preoperative diagnostic accuracy.Materials and Methods: Patients with SWI studies of the brain and pathology-confirmed PCNSL, high-grade glioma,or intraaxial metastatic lesions between 2009 and 2015 were reviewed. On SWI, those whose deep medullary veinscould be visualized within 5-mm range of the enhancing tumor were enrolled into the study. A total of 27 patients wererecruited and images were reviewed for signs of medullary vein blockage (MVB). MVB was defined as a deepmedullary vein terminating at the margin of the tumor. The sensitivity, specificity, and diagnostic accuracy of MVB indifferentiating PCNSL, high-grade glioma, and metastasis were analyzed.Results: A total of 11 PCNSL, 5 high-grade gliomas, and 11 metastatic cases were reviewed. MVB was not identifiedin any of imaging studies for PCNSL or high-grade glioma patients. However, MVB was noted in 9 of 11 metastatictumors (81.8{\%}). The MVB sign showed a diagnostic specificity and accuracy of 100{\%} and 92.6{\%}, respectively, forintraaxial metastatic tumors.Conclusion: The MVB sign on SWI images has a high accuracy and specificity for differentiating metastatic braintumors from PCNSL, high-grade gliomas and thus may aid physicians in treatment planning.",
author = "Shih-Hung Yang and Chien-Tai Hong and Chia-Yuen Chen and Wei-Yu Chen and Tsai, {Fong Y.} and Chan, {Wing P.}",
year = "2017",
month = "3",
language = "English",
note = "The 66th Annual Meeting of RSROC ; Conference date: 18-03-2017 Through 19-03-2017",
url = "https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=93",

}

TY - CONF

T1 - Medullary Vein Blockage Sign Detected by Susceptibility-Weighted Imaging for Diagnosing Metastatic Brain Tumors

AU - Yang, Shih-Hung

AU - Hong, Chien-Tai

AU - Chen, Chia-Yuen

AU - Chen, Wei-Yu

AU - Tsai, Fong Y.

AU - Chan, Wing P.

PY - 2017/3

Y1 - 2017/3

N2 - Purpose: The aim of this study was to identify an anatomical relationship between deep medullary vein and these threecommon brain tumors, which may improve preoperative diagnostic accuracy.Materials and Methods: Patients with SWI studies of the brain and pathology-confirmed PCNSL, high-grade glioma,or intraaxial metastatic lesions between 2009 and 2015 were reviewed. On SWI, those whose deep medullary veinscould be visualized within 5-mm range of the enhancing tumor were enrolled into the study. A total of 27 patients wererecruited and images were reviewed for signs of medullary vein blockage (MVB). MVB was defined as a deepmedullary vein terminating at the margin of the tumor. The sensitivity, specificity, and diagnostic accuracy of MVB indifferentiating PCNSL, high-grade glioma, and metastasis were analyzed.Results: A total of 11 PCNSL, 5 high-grade gliomas, and 11 metastatic cases were reviewed. MVB was not identifiedin any of imaging studies for PCNSL or high-grade glioma patients. However, MVB was noted in 9 of 11 metastatictumors (81.8%). The MVB sign showed a diagnostic specificity and accuracy of 100% and 92.6%, respectively, forintraaxial metastatic tumors.Conclusion: The MVB sign on SWI images has a high accuracy and specificity for differentiating metastatic braintumors from PCNSL, high-grade gliomas and thus may aid physicians in treatment planning.

AB - Purpose: The aim of this study was to identify an anatomical relationship between deep medullary vein and these threecommon brain tumors, which may improve preoperative diagnostic accuracy.Materials and Methods: Patients with SWI studies of the brain and pathology-confirmed PCNSL, high-grade glioma,or intraaxial metastatic lesions between 2009 and 2015 were reviewed. On SWI, those whose deep medullary veinscould be visualized within 5-mm range of the enhancing tumor were enrolled into the study. A total of 27 patients wererecruited and images were reviewed for signs of medullary vein blockage (MVB). MVB was defined as a deepmedullary vein terminating at the margin of the tumor. The sensitivity, specificity, and diagnostic accuracy of MVB indifferentiating PCNSL, high-grade glioma, and metastasis were analyzed.Results: A total of 11 PCNSL, 5 high-grade gliomas, and 11 metastatic cases were reviewed. MVB was not identifiedin any of imaging studies for PCNSL or high-grade glioma patients. However, MVB was noted in 9 of 11 metastatictumors (81.8%). The MVB sign showed a diagnostic specificity and accuracy of 100% and 92.6%, respectively, forintraaxial metastatic tumors.Conclusion: The MVB sign on SWI images has a high accuracy and specificity for differentiating metastatic braintumors from PCNSL, high-grade gliomas and thus may aid physicians in treatment planning.

M3 - Paper

ER -