次發性副甲狀腺機能亢進的治療

Translated title of the contribution: Medical Treatment of Secondary Hyperparathyroidism

Research output: Contribution to journalArticle

Abstract

Secondary hyperparathyroidism is one of the most common complications in patients with chronic kidney disease. These patients frequently complicated with disorders of mineral and bone metabolism and cardiovascular disease. The pathophysiology of secondary hyperparathyroid disorder is complex and involves hypocalcemia, hyperphosphatemia and decreased calcitriol activity. The treatment of patients with hyperparathyroidism varies depending upon correction of hypocalcemia and hyperphosphatemia by restricting dietary phosphate intake, administering phosphate binders and vitamin D supplement in calcitriol deficiency. Calcimimetics is the alternative treatment in patients complicated with hypercalcemia. Parathyroidectomy is indicated when medical treatment fails. Efficacy of ultrasound-guided percutaneous ethanol or vitamin D injection therapy remained to be determined.
Original languageTraditional Chinese
Pages (from-to)135-140
Number of pages6
Journal腎臟與透析
Volume27
Issue number3
DOIs
Publication statusPublished - 2015

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Secondary Hyperparathyroidism
Hyperphosphatemia
Hypocalcemia
Calcitriol
Vitamin D
Phosphates
Parathyroidectomy
Hyperparathyroidism
Bone Diseases
Hypercalcemia
Therapeutics
Chronic Renal Insufficiency
Minerals
Ethanol
Cardiovascular Diseases
Injections

Cite this

次發性副甲狀腺機能亢進的治療. / 劉峻瑋(Chun-Wei Liu); 鄭仲益(Chung-Yi Cheng); 陳作孝(Tso-Hsiao Chen).

In: 腎臟與透析, Vol. 27, No. 3, 2015, p. 135-140.

Research output: Contribution to journalArticle

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title = "次發性副甲狀腺機能亢進的治療",
abstract = "次發性副甲狀腺機能亢進是慢性腎臟病病患最常見的併發症之一,罹病患者易併發腎性骨病變及心血管疾病。其致病機轉主要為低血鈣、高血磷與活性維生素D的缺乏。傳統治療上以飲食與藥物來改善低血鈣與高血磷症,以活性維生素D治療維生素D缺乏,當病患發生高血鈣與血管鈣化副作用時,擬鈣劑則是另一種藥物的選擇,副甲狀腺切除術適應於藥物治療無效時。以酒精或是高濃度維生素D注射於副甲狀腺結節上,目前未有研究定論其長期療效。",
keywords = "副甲狀腺機能亢進, 纖維母細胞生長因子-23, 血磷, Hyperparathyroidism, FGF-23, phosphate",
author = "劉, {峻瑋(Chun-Wei Liu)} and 鄭, {仲益(Chung-Yi Cheng)} and 陳, {作孝(Tso-Hsiao Chen)}",
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AU - 陳, 作孝(Tso-Hsiao Chen)

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KW - 副甲狀腺機能亢進

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