Mechanism of fulminant pulmonary edema caused by enterovirus 71

Shang Jyh Kao, Fwu Lin Yang, Yung Hsiang Ksu, Hsing I. Chen

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Pulmonary edema (PE) may occur with enterovirus 71 (EV71) infection. We monitored arterial pressure (AP) and heart rate (HR) in patients with EV71 infection and analyzed the variability of AP and HR. Sympathetic activity, AP, and HR increased with respiratory stress. Thereafter, parasympathetic activity increased with decreases in AP and HR. The lungs showed edema with inducible nitric oxide synthase (iNOS) expression. Destruction of the medial, ventral, and caudal medulla may lead to sympathetic overactivation, causing blood to shift to the lungs. The pathogenesis of PE may also involve iNOS and nitric oxide.

Original languageEnglish
Pages (from-to)1784-1788
Number of pages5
JournalClinical Infectious Diseases
Volume38
Issue number12
DOIs
Publication statusPublished - Jun 15 2004

ASJC Scopus subject areas

  • Immunology

Fingerprint Dive into the research topics of 'Mechanism of fulminant pulmonary edema caused by enterovirus 71'. Together they form a unique fingerprint.

  • Cite this

    Kao, S. J., Yang, F. L., Ksu, Y. H., & Chen, H. I. (2004). Mechanism of fulminant pulmonary edema caused by enterovirus 71. Clinical Infectious Diseases, 38(12), 1784-1788. https://doi.org/10.1086/421021