Mechanical comparison of biodegradable femoral fixation devices for hamstring tendon graft - A biomechanical study in a porcine model

Jia Lin Wu, Tsu Te Yeh, Hsain Chung Shen, Cheng Kung Cheng, Chian Her Lee

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Initial fixation strength is critical for the early post-operative rehabilitation of patients with anterior cruciate ligament reconstructions. However, even the best femoral fixation devices remain controversial. We compared the biomechanical characteristics of tendon grafts fixed by different biodegradable femoral fixation devices following anterior cruciate ligament reconstruction. Methods: The Bio-TransFix, Rigidfix, Bioscrew with EndoPearl augmentation and Bioscrew devices were used to fix porcine flexor digitorum profundus tendon grafts in 32 porcine femora. Displacement of each tendon graft was evaluated after cyclic loading testing. Stiffness, ultimate failure load and failure mode of these fixation devices were measured with load-to-failure testing. Findings: The displacement of the femur-graft-cement complex in response to cyclic loading was lower (P <0.05) for the Bio-TransFix than the Rigidfix, Bioscrew with EndoPearl augmentation, and Bioscrew groups. The fixation stiffness values of the Rigidfix and the Bioscrew were significantly greater (P <0.05) than that of the Bio-TransFix. The ultimate failure load was significantly greater for the Bio-TransFix and the Rigidfix than the Bioscrew with EndoPearl augmentation or the Bioscrew (P <0.05). Interpretation: The Bio-TransFix provided the least graft displacement under cyclic loading. However, this device gave less stability. The Rigidfix device provided better stability and stiffness of the tendon graft among those fixation devices that showed no significant differences in graft displacement under cyclic loading. However, no single fixation device provided less displacement along with a larger failure load and stiffness in this study.

Original languageEnglish
Pages (from-to)435-440
Number of pages6
JournalClinical Biomechanics
Volume24
Issue number5
DOIs
Publication statusPublished - Jun 2009
Externally publishedYes

Fingerprint

Thigh
Swine
Transplants
Equipment and Supplies
Tendons
Anterior Cruciate Ligament Reconstruction
Femur
Hamstring Tendons
Rehabilitation

Keywords

  • Anterior cruciate ligament reconstruction
  • Biodegradable device
  • Biomechanics
  • Hamstring graft

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Biophysics

Cite this

Mechanical comparison of biodegradable femoral fixation devices for hamstring tendon graft - A biomechanical study in a porcine model. / Wu, Jia Lin; Yeh, Tsu Te; Shen, Hsain Chung; Cheng, Cheng Kung; Lee, Chian Her.

In: Clinical Biomechanics, Vol. 24, No. 5, 06.2009, p. 435-440.

Research output: Contribution to journalArticle

@article{044cd399a6654e3699d8b20d64a9f70d,
title = "Mechanical comparison of biodegradable femoral fixation devices for hamstring tendon graft - A biomechanical study in a porcine model",
abstract = "Background: Initial fixation strength is critical for the early post-operative rehabilitation of patients with anterior cruciate ligament reconstructions. However, even the best femoral fixation devices remain controversial. We compared the biomechanical characteristics of tendon grafts fixed by different biodegradable femoral fixation devices following anterior cruciate ligament reconstruction. Methods: The Bio-TransFix, Rigidfix, Bioscrew with EndoPearl augmentation and Bioscrew devices were used to fix porcine flexor digitorum profundus tendon grafts in 32 porcine femora. Displacement of each tendon graft was evaluated after cyclic loading testing. Stiffness, ultimate failure load and failure mode of these fixation devices were measured with load-to-failure testing. Findings: The displacement of the femur-graft-cement complex in response to cyclic loading was lower (P <0.05) for the Bio-TransFix than the Rigidfix, Bioscrew with EndoPearl augmentation, and Bioscrew groups. The fixation stiffness values of the Rigidfix and the Bioscrew were significantly greater (P <0.05) than that of the Bio-TransFix. The ultimate failure load was significantly greater for the Bio-TransFix and the Rigidfix than the Bioscrew with EndoPearl augmentation or the Bioscrew (P <0.05). Interpretation: The Bio-TransFix provided the least graft displacement under cyclic loading. However, this device gave less stability. The Rigidfix device provided better stability and stiffness of the tendon graft among those fixation devices that showed no significant differences in graft displacement under cyclic loading. However, no single fixation device provided less displacement along with a larger failure load and stiffness in this study.",
keywords = "Anterior cruciate ligament reconstruction, Biodegradable device, Biomechanics, Hamstring graft",
author = "Wu, {Jia Lin} and Yeh, {Tsu Te} and Shen, {Hsain Chung} and Cheng, {Cheng Kung} and Lee, {Chian Her}",
year = "2009",
month = "6",
doi = "10.1016/j.clinbiomech.2009.02.003",
language = "English",
volume = "24",
pages = "435--440",
journal = "Clinical Biomechanics",
issn = "0268-0033",
publisher = "Elsevier Limited",
number = "5",

}

TY - JOUR

T1 - Mechanical comparison of biodegradable femoral fixation devices for hamstring tendon graft - A biomechanical study in a porcine model

AU - Wu, Jia Lin

AU - Yeh, Tsu Te

AU - Shen, Hsain Chung

AU - Cheng, Cheng Kung

AU - Lee, Chian Her

PY - 2009/6

Y1 - 2009/6

N2 - Background: Initial fixation strength is critical for the early post-operative rehabilitation of patients with anterior cruciate ligament reconstructions. However, even the best femoral fixation devices remain controversial. We compared the biomechanical characteristics of tendon grafts fixed by different biodegradable femoral fixation devices following anterior cruciate ligament reconstruction. Methods: The Bio-TransFix, Rigidfix, Bioscrew with EndoPearl augmentation and Bioscrew devices were used to fix porcine flexor digitorum profundus tendon grafts in 32 porcine femora. Displacement of each tendon graft was evaluated after cyclic loading testing. Stiffness, ultimate failure load and failure mode of these fixation devices were measured with load-to-failure testing. Findings: The displacement of the femur-graft-cement complex in response to cyclic loading was lower (P <0.05) for the Bio-TransFix than the Rigidfix, Bioscrew with EndoPearl augmentation, and Bioscrew groups. The fixation stiffness values of the Rigidfix and the Bioscrew were significantly greater (P <0.05) than that of the Bio-TransFix. The ultimate failure load was significantly greater for the Bio-TransFix and the Rigidfix than the Bioscrew with EndoPearl augmentation or the Bioscrew (P <0.05). Interpretation: The Bio-TransFix provided the least graft displacement under cyclic loading. However, this device gave less stability. The Rigidfix device provided better stability and stiffness of the tendon graft among those fixation devices that showed no significant differences in graft displacement under cyclic loading. However, no single fixation device provided less displacement along with a larger failure load and stiffness in this study.

AB - Background: Initial fixation strength is critical for the early post-operative rehabilitation of patients with anterior cruciate ligament reconstructions. However, even the best femoral fixation devices remain controversial. We compared the biomechanical characteristics of tendon grafts fixed by different biodegradable femoral fixation devices following anterior cruciate ligament reconstruction. Methods: The Bio-TransFix, Rigidfix, Bioscrew with EndoPearl augmentation and Bioscrew devices were used to fix porcine flexor digitorum profundus tendon grafts in 32 porcine femora. Displacement of each tendon graft was evaluated after cyclic loading testing. Stiffness, ultimate failure load and failure mode of these fixation devices were measured with load-to-failure testing. Findings: The displacement of the femur-graft-cement complex in response to cyclic loading was lower (P <0.05) for the Bio-TransFix than the Rigidfix, Bioscrew with EndoPearl augmentation, and Bioscrew groups. The fixation stiffness values of the Rigidfix and the Bioscrew were significantly greater (P <0.05) than that of the Bio-TransFix. The ultimate failure load was significantly greater for the Bio-TransFix and the Rigidfix than the Bioscrew with EndoPearl augmentation or the Bioscrew (P <0.05). Interpretation: The Bio-TransFix provided the least graft displacement under cyclic loading. However, this device gave less stability. The Rigidfix device provided better stability and stiffness of the tendon graft among those fixation devices that showed no significant differences in graft displacement under cyclic loading. However, no single fixation device provided less displacement along with a larger failure load and stiffness in this study.

KW - Anterior cruciate ligament reconstruction

KW - Biodegradable device

KW - Biomechanics

KW - Hamstring graft

UR - http://www.scopus.com/inward/record.url?scp=64949185966&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=64949185966&partnerID=8YFLogxK

U2 - 10.1016/j.clinbiomech.2009.02.003

DO - 10.1016/j.clinbiomech.2009.02.003

M3 - Article

VL - 24

SP - 435

EP - 440

JO - Clinical Biomechanics

JF - Clinical Biomechanics

SN - 0268-0033

IS - 5

ER -