Abstract
Objective: To present the maternal and female fetal virilization caused by excessive androgen secretion of pregnancy luteomas. Design: Case report. Setting: University-based teaching hospital. Patient(s): A nulligravida woman suffering from bilateral hydronephrosis and recurrent acute pyelonephritis caused by bilateral solid ovarian tumors presented virilization during the third trimester. Without prompt surgical intervention, the maternal hyperandrogenemia returned to a normal level and regression of bilateral ovarian tumors occurred spontaneously after a female fetus with clitoral hypertrophy and temporal hyperandrogenemia was delivered. In spite of lacking histology, the clinical course is compared to that of pregnancy luteomas. Intervention(s): Noninvasive imaging assessment. Main Outcome Measure(s): Maternal and female fetal virilization. Result(s): Regression of androgen-secreting pregnancy luteomas and hyperandrogenism during the puerperium but apparent female fetal clitoral hypertrophy. Conclusion(s): The maternal and female fetal virilization was caused by exaggerating androgen secretion of bilateral ovarian solid tumors. Spontaneous regression of ovarian tumors and hyperandrogenemia during the puerperium is the natural course of pregnancy luteomas, not true neoplasms.
| Original language | English |
|---|---|
| Journal | Fertility and Sterility |
| Volume | 84 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Aug 2005 |
| Externally published | Yes |
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Keywords
- Hdronephrosis
- Hperreactio luteinalis
- Pregnancy luteomas
- Vrilization
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Maternal and female fetal virilization caused by pregnancy luteomas. / Wang, Yu Chi; Su, Her Young; Liu, Jah Yao; Chang, Fung Wei; Chen, Chi Huang.
In: Fertility and Sterility, Vol. 84, No. 2, 08.2005.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Maternal and female fetal virilization caused by pregnancy luteomas
AU - Wang, Yu Chi
AU - Su, Her Young
AU - Liu, Jah Yao
AU - Chang, Fung Wei
AU - Chen, Chi Huang
PY - 2005/8
Y1 - 2005/8
N2 - Objective: To present the maternal and female fetal virilization caused by excessive androgen secretion of pregnancy luteomas. Design: Case report. Setting: University-based teaching hospital. Patient(s): A nulligravida woman suffering from bilateral hydronephrosis and recurrent acute pyelonephritis caused by bilateral solid ovarian tumors presented virilization during the third trimester. Without prompt surgical intervention, the maternal hyperandrogenemia returned to a normal level and regression of bilateral ovarian tumors occurred spontaneously after a female fetus with clitoral hypertrophy and temporal hyperandrogenemia was delivered. In spite of lacking histology, the clinical course is compared to that of pregnancy luteomas. Intervention(s): Noninvasive imaging assessment. Main Outcome Measure(s): Maternal and female fetal virilization. Result(s): Regression of androgen-secreting pregnancy luteomas and hyperandrogenism during the puerperium but apparent female fetal clitoral hypertrophy. Conclusion(s): The maternal and female fetal virilization was caused by exaggerating androgen secretion of bilateral ovarian solid tumors. Spontaneous regression of ovarian tumors and hyperandrogenemia during the puerperium is the natural course of pregnancy luteomas, not true neoplasms.
AB - Objective: To present the maternal and female fetal virilization caused by excessive androgen secretion of pregnancy luteomas. Design: Case report. Setting: University-based teaching hospital. Patient(s): A nulligravida woman suffering from bilateral hydronephrosis and recurrent acute pyelonephritis caused by bilateral solid ovarian tumors presented virilization during the third trimester. Without prompt surgical intervention, the maternal hyperandrogenemia returned to a normal level and regression of bilateral ovarian tumors occurred spontaneously after a female fetus with clitoral hypertrophy and temporal hyperandrogenemia was delivered. In spite of lacking histology, the clinical course is compared to that of pregnancy luteomas. Intervention(s): Noninvasive imaging assessment. Main Outcome Measure(s): Maternal and female fetal virilization. Result(s): Regression of androgen-secreting pregnancy luteomas and hyperandrogenism during the puerperium but apparent female fetal clitoral hypertrophy. Conclusion(s): The maternal and female fetal virilization was caused by exaggerating androgen secretion of bilateral ovarian solid tumors. Spontaneous regression of ovarian tumors and hyperandrogenemia during the puerperium is the natural course of pregnancy luteomas, not true neoplasms.
KW - Hdronephrosis
KW - Hperreactio luteinalis
KW - Pregnancy luteomas
KW - Vrilization
UR - http://www.scopus.com/inward/record.url?scp=23744457607&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=23744457607&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2005.02.029
DO - 10.1016/j.fertnstert.2005.02.029
M3 - Article
C2 - 16086574
AN - SCOPUS:23744457607
VL - 84
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 2
ER -