Masseter Muscle Volume Changes Evaluated by 3-Dimensional Computed Tomography After Repeated Botulinum Toxin A Injections in Patients With Square Facial Morphology

Chun Shin Chang, Susie Lin, Christopher Glenn Wallace, Yen Chang Hsiao, Che Min Lin, Gavin Chun Wui Kang, Zung Chung Chen, Philip Kuo Ting Chen, Lun Jou Lo, Yu Ray Chen, Jyh Ping Chen

Research output: Contribution to journalArticle

Abstract

INTRODUCTION: Botulinum neurotoxin A (BoNT-A) is a minimally invasive and technically straightforward treatment of masseter muscle (MM) volume reduction and facial contouring, but the literature on its long-term effect on MM volume remains unclear. OBJECTIVE: This study aimed to assess quantitatively for progressive volume changes of lower facial contour after 3 BoNT-A injections in patients with bilateral MM hypertrophy causing square facial morphology using 3-dimensional computed tomographic scans. MATERIALS AND METHODS: Ten female patients with square facial morphology due to bilateral MM hypertrophy were recruited to, and 6 completed, this clinical study. Each received 24 U of BoNT-A into the inferior portion of each MM on both sides, repeated 6 monthly to complete 3 treatments. Masseter muscle volume changes were assessed using 3-dimensional computed tomography at pretreatment (before injections) and posttreatment (1 year after the third injection). RESULTS: Mean MM volume significantly reduced from 26.39 ± 4.18 cm before treatment to 23.26 ± 4.31 cm 1 year after treatment (P = 0.002). CONCLUSION: Three consecutive 6-monthly BoNT-A injections into the MMs reduced their volume by 12% when assessed 1 year after completion of treatment.

Original languageEnglish
Pages (from-to)S29-S32
JournalAnnals of Plastic Surgery
Volume82
Issue number1S Suppl 1
DOIs
Publication statusPublished - Jan 1 2019
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Surgery

Cite this

Chang, C. S., Lin, S., Wallace, C. G., Hsiao, Y. C., Lin, C. M., Kang, G. C. W., Chen, Z. C., Chen, P. K. T., Lo, L. J., Chen, Y. R., & Chen, J. P. (2019). Masseter Muscle Volume Changes Evaluated by 3-Dimensional Computed Tomography After Repeated Botulinum Toxin A Injections in Patients With Square Facial Morphology. Annals of Plastic Surgery, 82(1S Suppl 1), S29-S32. https://doi.org/10.1097/SAP.0000000000001705