Mass Spectra Analyses of Amides and Amide Dimers of Steviol, Isosteviol, and Steviolbioside

Ling-Wen Lee, Tzong Huei Lee, Ching Tung Lin, Tiffany Chen, Pen-Yuan Lin

Research output: Contribution to journalArticle

Abstract

The mass spectra of a series of stevioside analogues including the amide and dimer compounds of steviol, isosteviol, and steviolbioside were examined. Positive ion mass spectral fragmentation of new steviol, isosteviol, and steviolbioside amides and the amide dimers are reported and discussed. The techniques included their synthesis procedures, fast-atom bombardment (FAB), and LC/MS/MS mass spectra. Intense [M+H]+ and [M+Na]+ ion peaks were observed on the FAB and ESI spectra. LC/MS/MS also yielded ES+ and ES− ion peaks that fairly agreed with the results of the FAB and ESI studies. Mass spectral analysis of compounds 4p-q, 5a-g, 6, and 7 revealed the different cleavage pathway patterns that can help in identifying the structures of steviolbioside and its amide derivatives.
Original languageEnglish
JournalInternational Journal of Spectroscopy
Publication statusPublished - 2012

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Amides
Dimers
Atoms
Ions
Spectrum analysis
Positive ions
Derivatives
steviol
steviolbioside
isosteviol

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Mass Spectra Analyses of Amides and Amide Dimers of Steviol, Isosteviol, and Steviolbioside. / Lee, Ling-Wen; Lee, Tzong Huei; Lin, Ching Tung; Chen, Tiffany; Lin, Pen-Yuan.

In: International Journal of Spectroscopy, 2012.

Research output: Contribution to journalArticle

Lee, Ling-Wen ; Lee, Tzong Huei ; Lin, Ching Tung ; Chen, Tiffany ; Lin, Pen-Yuan. / Mass Spectra Analyses of Amides and Amide Dimers of Steviol, Isosteviol, and Steviolbioside. In: International Journal of Spectroscopy. 2012.
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abstract = "The mass spectra of a series of stevioside analogues including the amide and dimer compounds of steviol, isosteviol, and steviolbioside were examined. Positive ion mass spectral fragmentation of new steviol, isosteviol, and steviolbioside amides and the amide dimers are reported and discussed. The techniques included their synthesis procedures, fast-atom bombardment (FAB), and LC/MS/MS mass spectra. Intense [M+H]+ and [M+Na]+ ion peaks were observed on the FAB and ESI spectra. LC/MS/MS also yielded ES+ and ES− ion peaks that fairly agreed with the results of the FAB and ESI studies. Mass spectral analysis of compounds 4p-q, 5a-g, 6, and 7 revealed the different cleavage pathway patterns that can help in identifying the structures of steviolbioside and its amide derivatives.",
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AU - Lee, Ling-Wen

AU - Lee, Tzong Huei

AU - Lin, Ching Tung

AU - Chen, Tiffany

AU - Lin, Pen-Yuan

PY - 2012

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AB - The mass spectra of a series of stevioside analogues including the amide and dimer compounds of steviol, isosteviol, and steviolbioside were examined. Positive ion mass spectral fragmentation of new steviol, isosteviol, and steviolbioside amides and the amide dimers are reported and discussed. The techniques included their synthesis procedures, fast-atom bombardment (FAB), and LC/MS/MS mass spectra. Intense [M+H]+ and [M+Na]+ ion peaks were observed on the FAB and ESI spectra. LC/MS/MS also yielded ES+ and ES− ion peaks that fairly agreed with the results of the FAB and ESI studies. Mass spectral analysis of compounds 4p-q, 5a-g, 6, and 7 revealed the different cleavage pathway patterns that can help in identifying the structures of steviolbioside and its amide derivatives.

M3 - Article

JO - International Journal of Spectroscopy

JF - International Journal of Spectroscopy

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