Marrow or Peripheral Blood for Hematopoietic Engraftment

Ronald D. Barr, Jacqueline Whang-Peng, Seymour Perry, Rainer Storb, Ross Prentice, E. Donnall Thomas

Research output: Contribution to journalLetter

3 Citations (Scopus)

Abstract

To the Editor: Implicit in the suggestion of Storb et al.1 that normal human peripheral blood may be used as a supplementary source of cells for hematopoietic engraftment is the belief that true hematopoietic stem cells circulate. This is a view with which we concur,2 and it has the support of circumstantial evidence derived from clinical experience.3 4 5 In this regard it should be noted that the demonstrable presence, in human blood, of progenitor cells committed to differentiation along established pathways6 7 8 9 10 is irrelevant to the goal of successful engraftment, since these cells have a limited capacity for self-replication.11 Using an.

Original languageEnglish
Pages (from-to)57-58
Number of pages2
JournalNew England Journal of Medicine
Volume297
Issue number1
DOIs
Publication statusPublished - Jul 7 1977
Externally publishedYes

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Bone Marrow
Hematopoietic Stem Cells
Blood Cells
Stem Cells

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Marrow or Peripheral Blood for Hematopoietic Engraftment. / Barr, Ronald D.; Whang-Peng, Jacqueline; Perry, Seymour; Storb, Rainer; Prentice, Ross; Thomas, E. Donnall.

In: New England Journal of Medicine, Vol. 297, No. 1, 07.07.1977, p. 57-58.

Research output: Contribution to journalLetter

Barr, Ronald D. ; Whang-Peng, Jacqueline ; Perry, Seymour ; Storb, Rainer ; Prentice, Ross ; Thomas, E. Donnall. / Marrow or Peripheral Blood for Hematopoietic Engraftment. In: New England Journal of Medicine. 1977 ; Vol. 297, No. 1. pp. 57-58.
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AU - Thomas, E. Donnall

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