Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise

Ching Chien Chang, Chia Wen Chen, Eddy Owaga, Wan Ting Lee, Ting Ni Liu, Rong Hong Hsieh

Research output: Contribution to journalArticle

Abstract

High-strength or long-duration exercise can lead to significant fatigue, oxidative stress, and muscle damage. The purpose of this study was to examine the effect of mangosteen concentrate drink (MCD) supplementation on antioxidant capacity and lactate clearance in rats after running exercise. Forty rats were divided into five groups: N, non-treatment; C, control; or supplemented with MCD, including M1, M5, and M10 (0.9, 4.5, and 9 mL/day) for 6 weeks. The rats were subjected to 30 min running and exhaustive-running tests using a treadmill. The blood lactate; triglyceride; cholesterol and glucose levels; hepatic and muscular malonaldehyde (MDA) levels; and antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), were analyzed. The results of this study demonstrated that MCD supplementation can increase GPx and CAT activities, alleviate oxidative stress in muscle, and increase lactate clearance, and is thereby beneficial to reduced muscle fatigue after exercise.

Original languageEnglish
Article number1447
JournalNutrients
Volume12
Issue number5
DOIs
Publication statusPublished - May 17 2020

Keywords

  • antioxidant capacity
  • exercise
  • lactate clearance
  • mangosteen
  • oxidative stress
  • Oxidative stress
  • Exercise
  • Lactate clearance
  • Mangosteen
  • Antioxidant capacity

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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