Management of symptomatic hamartomatous polyps in stomach: Analysis of a single center experience

Jung-Chun Lin, Tien-Yu Huang, Yu-Lueng Shih, Yi-Ming Chang, Heng-Cheng Chu, Wei-Kuo Chang, Tsai-Yuan Hsieh, Peng-Jen Chen

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: No consensus has been reached on the management of gastric hamartomatous polyps, owing to a lack of knowledge of the long-term outcome of after removal of these polyps. Methods: A retrospective database review was performed in a tertiary referral hospital between 1995 and 2011. Thirty-two consecutive patients who were diagnosed with gastric hamartomatous polyps were managed by surgical or endoscopic resection. Results: Patients developed the disease predominantly in their seventh and eighth decades of life. The tumors were located mostly in the antrum, and the diameter ranged from 5 to 52 mm. In one patient, adenocarcinoma in situ accompanied by gastric hamartomatous polyp was diagnosed by pathologic examination after endoscopic mucosal resection (EMR).There were no significant differences in the rates of technical success, treatment success, complications, or recurrence between surgery and endoscopic excision. The endoscopic excision group had a shorter mean post procedure hospital stay than the surgery group (7.2 vs. 21.4 days, P = 0.002). Conclusions: Endoscoipic resection for gastric hamartomatous polyps is an effective procedure and a less-invasive alternative to surgery. © 2013 JMS.
Original languageEnglish
Pages (from-to)29-36
Number of pages8
JournalJournal of Medical Sciences (Taiwan)
Volume33
Issue number1
DOIs
Publication statusPublished - 2013
Externally publishedYes

Fingerprint

Polyps
Stomach
Tertiary Care Centers
Length of Stay
Databases
Recurrence
Neoplasms
Therapeutics

Keywords

  • Endoscopic resection
  • Gastric polyp
  • Hamartomatous polyp
  • adult
  • aged
  • article
  • clinical article
  • clinical effectiveness
  • endoscopic surgery
  • female
  • follow up
  • gastric hamartomatous polyp
  • human
  • intermethod comparison
  • length of stay
  • male
  • postoperative hemorrhage
  • retrospective study
  • stomach adenocarcinoma
  • stomach perforation
  • stomach polyp
  • stomach surgery
  • treatment outcome
  • tumor localization
  • urinary tract infection

Cite this

Management of symptomatic hamartomatous polyps in stomach: Analysis of a single center experience. / Lin, Jung-Chun; Huang, Tien-Yu; Shih, Yu-Lueng; Chang, Yi-Ming; Chu, Heng-Cheng; Chang, Wei-Kuo; Hsieh, Tsai-Yuan; Chen, Peng-Jen.

In: Journal of Medical Sciences (Taiwan), Vol. 33, No. 1, 2013, p. 29-36.

Research output: Contribution to journalArticle

Lin, Jung-Chun ; Huang, Tien-Yu ; Shih, Yu-Lueng ; Chang, Yi-Ming ; Chu, Heng-Cheng ; Chang, Wei-Kuo ; Hsieh, Tsai-Yuan ; Chen, Peng-Jen. / Management of symptomatic hamartomatous polyps in stomach: Analysis of a single center experience. In: Journal of Medical Sciences (Taiwan). 2013 ; Vol. 33, No. 1. pp. 29-36.
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abstract = "Background: No consensus has been reached on the management of gastric hamartomatous polyps, owing to a lack of knowledge of the long-term outcome of after removal of these polyps. Methods: A retrospective database review was performed in a tertiary referral hospital between 1995 and 2011. Thirty-two consecutive patients who were diagnosed with gastric hamartomatous polyps were managed by surgical or endoscopic resection. Results: Patients developed the disease predominantly in their seventh and eighth decades of life. The tumors were located mostly in the antrum, and the diameter ranged from 5 to 52 mm. In one patient, adenocarcinoma in situ accompanied by gastric hamartomatous polyp was diagnosed by pathologic examination after endoscopic mucosal resection (EMR).There were no significant differences in the rates of technical success, treatment success, complications, or recurrence between surgery and endoscopic excision. The endoscopic excision group had a shorter mean post procedure hospital stay than the surgery group (7.2 vs. 21.4 days, P = 0.002). Conclusions: Endoscoipic resection for gastric hamartomatous polyps is an effective procedure and a less-invasive alternative to surgery. {\circledC} 2013 JMS.",
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author = "Jung-Chun Lin and Tien-Yu Huang and Yu-Lueng Shih and Yi-Ming Chang and Heng-Cheng Chu and Wei-Kuo Chang and Tsai-Yuan Hsieh and Peng-Jen Chen",
note = "被引用次數:3 Export Date: 22 March 2016 通訊地址: Chen, P.-J.; Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec 2, Cheng-Gong Road, Taipei 114, Taiwan; 電子郵件: doc12983@gmail.com 參考文獻: Aoki, M., Yoshida, M., Saikawa, Y., Otani, Y., Kubota, T., Kumai, K., Wakabayashi, G., Kitajima, M., Diagnosis and treatment of a gastric hamartomatous inverted polyp: Report of a case (2004) Surg Today, 34, pp. 532-536; Ono, S., Kamoshida, T., Hiroshima, Y., Okawara, A., Matsuo, T., Kakinoki, N., Ishikawa, A., Shimokama, T., A case of early gastric cancer accompanied by a hamartomatous inverted polyp and successfully managed with endoscopic submucosal dissection (2007) Endoscopy, 39 (SUPPL. 1), pp. E202; Parkdo, Y., Lauwers, G.Y., Gastric polyps: Classification and management (2008) Arch Pathol Lab Med, 132, pp. 633-640; Odashima, M., Otaka, M., Nanjo, H., Jin, M., Horikawa, Y., Matsuhashi, T., Ohba, R., Watanabe, S., Hamartomatous inverted polyp successfully treated by endoscopic submucosal dissection (2008) Intern Med, 47, pp. 259-262; Iishi, H., Tatsuta, M., Okuda, S., Clinicopathological features and natural history of gastric hamartomatous polyps (1989) Dig Dis Sci, 34, pp. 890-894; Tatsuta, M., Okuda, S., Tamura, H., Taniguchi, H., Gastric hamartomatous polyps in the absence of familial polyposis coli (1980) Cancer, 45, pp. 818-823; Grisendi, A., Lonardo, A., Solitary Peutz-Jeghers type polyp of the stomach (1990) Endoscopy, 22, p. 153; Kuwano, H., Takano, H., Sugimachi, K., Solitary Peutz-Jeghers type polyp of the stomach in the absence of familial polyposis coli in a teenage boy (1989) Endoscopy, 21, pp. 188-190; Sato, T., Sakai, Y., Ishiguro, S., Fujita, M., Kuriyama, K., Narumi, Y., Gastric hamartomatous polyp without polyposis coli: Radiologic diagnosis (1988) Gastrointest Radiol, 13, pp. 19-23; Sipponen, P., Laxen, F., Seppala, K., Cystic 'hamartomatous' gastric polyps: A disorder of oxyntic glands (1983) Histopathology, 7, pp. 729-737; Erdozain, J.C., Sanchez-Ruano, J.J., San, R.A.L., Boixeda, D., Moreira, V.F., Plaza, A.G., Solitary gastric hamartomatous polyp and upper gastrointestinal haemorrhage: An exceptional presentation of an unusual diagnosis (1990) Postgrad Med J, 66, pp. 1084-1085; Sakadamis, A.K., Ballas, K.D., Fardellas, J.G., Papanikolaou, A., A solitary gastric Peutz-Jeghers type polyp: Report of a case (2001) Surg Today, 31, pp. 517-520; Itoh, K., Tsuchigame, T., Matsukawa, T., Takahashi, M., Honma, K., Ishimaru, Y., Unusual gastric polyp showing submucosal proliferation of glands: Case report and literature review (1998) J Gastroenterol, 33, pp. 720-723; Oh, S.J., Oh, C.A., Kim, D.H., Choi, M.G., Noh, J.H., Sohn, T.S., Kim, K.M., Kim, S., Adenocarcinoma derived from gastric hamartomatous polyps (2011) J Korean Surg Soc, 81, pp. 419-422; Hirasaki, S., Tanimizu, M., Moriwaki, T., Hyodo, I., Shinji, T., Koide, N., Shiratori, Y., Efficacy of clinical pathway for the management of mucosal gastric carcinoma treated with endoscopic submucosal dissection using an insulated-tip diathermic knife (2004) Intern Med, 43, pp. 1120-1125; Lee, I.L., Wu, C.S., Tung, S.Y., Lin, P.Y., Shen, C.H., Wei, K.L., Chang, T.S., Endoscopic submucosal dissection for early gastric cancers: Experience from a new endoscopic center in Taiwan (2008) J Clin Gastroenterol, 42, pp. 42-47; Chang, C.C., Lee, I.L., Chen, P.J., Wang, H.P., Hou, M.C., Lee, C.T., Chen, Y.Y., Lin, J.T., Endoscopic sub-mucosal dissection for gastric epithelial tumors: A multicenter study in Taiwan (2009) J Formos Med Assoc, 108, pp. 38-44; Elster, K., Eidt, H., Ottenjann, R., Rosch, W., Seifert, E., The glandular cyst, a polypoid lesion of the gastric mucosa (author's transl) (1977) Dtsch Med Wochenschr, 102, pp. 183-187; Oberhuber, G., Stolte, M., Gastric polyps: An update of their pathology and biological significance (2000) Virchows Arch, 437, pp. 581-590; Stolte, M., Clinical consequences of the endoscopic diagnosis of gastric polyps (1995) Endoscopy, 27, pp. 32-37. , discussion 59-60; Harada, H., Toyonaga, A., Ohmagari, K., Ikeda, H., Tankikawa, K., Endoscopic Resection of Small Gastric Adenoma (1997) Digestive Endoscopy, 9, p. 5",
year = "2013",
doi = "10.6136/JMS.2013.33(1).029",
language = "English",
volume = "33",
pages = "29--36",
journal = "Journal of Medical Sciences",
issn = "1011-4564",
publisher = "國防醫學院",
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TY - JOUR

T1 - Management of symptomatic hamartomatous polyps in stomach: Analysis of a single center experience

AU - Lin, Jung-Chun

AU - Huang, Tien-Yu

AU - Shih, Yu-Lueng

AU - Chang, Yi-Ming

AU - Chu, Heng-Cheng

AU - Chang, Wei-Kuo

AU - Hsieh, Tsai-Yuan

AU - Chen, Peng-Jen

N1 - 被引用次數:3 Export Date: 22 March 2016 通訊地址: Chen, P.-J.; Division of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec 2, Cheng-Gong Road, Taipei 114, Taiwan; 電子郵件: doc12983@gmail.com 參考文獻: Aoki, M., Yoshida, M., Saikawa, Y., Otani, Y., Kubota, T., Kumai, K., Wakabayashi, G., Kitajima, M., Diagnosis and treatment of a gastric hamartomatous inverted polyp: Report of a case (2004) Surg Today, 34, pp. 532-536; Ono, S., Kamoshida, T., Hiroshima, Y., Okawara, A., Matsuo, T., Kakinoki, N., Ishikawa, A., Shimokama, T., A case of early gastric cancer accompanied by a hamartomatous inverted polyp and successfully managed with endoscopic submucosal dissection (2007) Endoscopy, 39 (SUPPL. 1), pp. E202; Parkdo, Y., Lauwers, G.Y., Gastric polyps: Classification and management (2008) Arch Pathol Lab Med, 132, pp. 633-640; Odashima, M., Otaka, M., Nanjo, H., Jin, M., Horikawa, Y., Matsuhashi, T., Ohba, R., Watanabe, S., Hamartomatous inverted polyp successfully treated by endoscopic submucosal dissection (2008) Intern Med, 47, pp. 259-262; Iishi, H., Tatsuta, M., Okuda, S., Clinicopathological features and natural history of gastric hamartomatous polyps (1989) Dig Dis Sci, 34, pp. 890-894; Tatsuta, M., Okuda, S., Tamura, H., Taniguchi, H., Gastric hamartomatous polyps in the absence of familial polyposis coli (1980) Cancer, 45, pp. 818-823; Grisendi, A., Lonardo, A., Solitary Peutz-Jeghers type polyp of the stomach (1990) Endoscopy, 22, p. 153; Kuwano, H., Takano, H., Sugimachi, K., Solitary Peutz-Jeghers type polyp of the stomach in the absence of familial polyposis coli in a teenage boy (1989) Endoscopy, 21, pp. 188-190; Sato, T., Sakai, Y., Ishiguro, S., Fujita, M., Kuriyama, K., Narumi, Y., Gastric hamartomatous polyp without polyposis coli: Radiologic diagnosis (1988) Gastrointest Radiol, 13, pp. 19-23; Sipponen, P., Laxen, F., Seppala, K., Cystic 'hamartomatous' gastric polyps: A disorder of oxyntic glands (1983) Histopathology, 7, pp. 729-737; Erdozain, J.C., Sanchez-Ruano, J.J., San, R.A.L., Boixeda, D., Moreira, V.F., Plaza, A.G., Solitary gastric hamartomatous polyp and upper gastrointestinal haemorrhage: An exceptional presentation of an unusual diagnosis (1990) Postgrad Med J, 66, pp. 1084-1085; Sakadamis, A.K., Ballas, K.D., Fardellas, J.G., Papanikolaou, A., A solitary gastric Peutz-Jeghers type polyp: Report of a case (2001) Surg Today, 31, pp. 517-520; Itoh, K., Tsuchigame, T., Matsukawa, T., Takahashi, M., Honma, K., Ishimaru, Y., Unusual gastric polyp showing submucosal proliferation of glands: Case report and literature review (1998) J Gastroenterol, 33, pp. 720-723; Oh, S.J., Oh, C.A., Kim, D.H., Choi, M.G., Noh, J.H., Sohn, T.S., Kim, K.M., Kim, S., Adenocarcinoma derived from gastric hamartomatous polyps (2011) J Korean Surg Soc, 81, pp. 419-422; Hirasaki, S., Tanimizu, M., Moriwaki, T., Hyodo, I., Shinji, T., Koide, N., Shiratori, Y., Efficacy of clinical pathway for the management of mucosal gastric carcinoma treated with endoscopic submucosal dissection using an insulated-tip diathermic knife (2004) Intern Med, 43, pp. 1120-1125; Lee, I.L., Wu, C.S., Tung, S.Y., Lin, P.Y., Shen, C.H., Wei, K.L., Chang, T.S., Endoscopic submucosal dissection for early gastric cancers: Experience from a new endoscopic center in Taiwan (2008) J Clin Gastroenterol, 42, pp. 42-47; Chang, C.C., Lee, I.L., Chen, P.J., Wang, H.P., Hou, M.C., Lee, C.T., Chen, Y.Y., Lin, J.T., Endoscopic sub-mucosal dissection for gastric epithelial tumors: A multicenter study in Taiwan (2009) J Formos Med Assoc, 108, pp. 38-44; Elster, K., Eidt, H., Ottenjann, R., Rosch, W., Seifert, E., The glandular cyst, a polypoid lesion of the gastric mucosa (author's transl) (1977) Dtsch Med Wochenschr, 102, pp. 183-187; Oberhuber, G., Stolte, M., Gastric polyps: An update of their pathology and biological significance (2000) Virchows Arch, 437, pp. 581-590; Stolte, M., Clinical consequences of the endoscopic diagnosis of gastric polyps (1995) Endoscopy, 27, pp. 32-37. , discussion 59-60; Harada, H., Toyonaga, A., Ohmagari, K., Ikeda, H., Tankikawa, K., Endoscopic Resection of Small Gastric Adenoma (1997) Digestive Endoscopy, 9, p. 5

PY - 2013

Y1 - 2013

N2 - Background: No consensus has been reached on the management of gastric hamartomatous polyps, owing to a lack of knowledge of the long-term outcome of after removal of these polyps. Methods: A retrospective database review was performed in a tertiary referral hospital between 1995 and 2011. Thirty-two consecutive patients who were diagnosed with gastric hamartomatous polyps were managed by surgical or endoscopic resection. Results: Patients developed the disease predominantly in their seventh and eighth decades of life. The tumors were located mostly in the antrum, and the diameter ranged from 5 to 52 mm. In one patient, adenocarcinoma in situ accompanied by gastric hamartomatous polyp was diagnosed by pathologic examination after endoscopic mucosal resection (EMR).There were no significant differences in the rates of technical success, treatment success, complications, or recurrence between surgery and endoscopic excision. The endoscopic excision group had a shorter mean post procedure hospital stay than the surgery group (7.2 vs. 21.4 days, P = 0.002). Conclusions: Endoscoipic resection for gastric hamartomatous polyps is an effective procedure and a less-invasive alternative to surgery. © 2013 JMS.

AB - Background: No consensus has been reached on the management of gastric hamartomatous polyps, owing to a lack of knowledge of the long-term outcome of after removal of these polyps. Methods: A retrospective database review was performed in a tertiary referral hospital between 1995 and 2011. Thirty-two consecutive patients who were diagnosed with gastric hamartomatous polyps were managed by surgical or endoscopic resection. Results: Patients developed the disease predominantly in their seventh and eighth decades of life. The tumors were located mostly in the antrum, and the diameter ranged from 5 to 52 mm. In one patient, adenocarcinoma in situ accompanied by gastric hamartomatous polyp was diagnosed by pathologic examination after endoscopic mucosal resection (EMR).There were no significant differences in the rates of technical success, treatment success, complications, or recurrence between surgery and endoscopic excision. The endoscopic excision group had a shorter mean post procedure hospital stay than the surgery group (7.2 vs. 21.4 days, P = 0.002). Conclusions: Endoscoipic resection for gastric hamartomatous polyps is an effective procedure and a less-invasive alternative to surgery. © 2013 JMS.

KW - Endoscopic resection

KW - Gastric polyp

KW - Hamartomatous polyp

KW - adult

KW - aged

KW - article

KW - clinical article

KW - clinical effectiveness

KW - endoscopic surgery

KW - female

KW - follow up

KW - gastric hamartomatous polyp

KW - human

KW - intermethod comparison

KW - length of stay

KW - male

KW - postoperative hemorrhage

KW - retrospective study

KW - stomach adenocarcinoma

KW - stomach perforation

KW - stomach polyp

KW - stomach surgery

KW - treatment outcome

KW - tumor localization

KW - urinary tract infection

U2 - 10.6136/JMS.2013.33(1).029

DO - 10.6136/JMS.2013.33(1).029

M3 - Article

VL - 33

SP - 29

EP - 36

JO - Journal of Medical Sciences

JF - Journal of Medical Sciences

SN - 1011-4564

IS - 1

ER -