Malignant rhabdoid tumour of the kidney occurring simultaneously with a brain tumour: A report of two cases and review of the literature

Chih Cheng Luo, Jer N. Lin, Tang H. Jaing, Chao Ping Yang, Chuen Hsueh

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Malignant rhabdoid tumour of the kidney (MRTK), an uncommon aggressive neoplasm of children, is now recognised as a separate entity from Wilms' tumour with distinct clinical and pathological features. MRTK is unique in its significant association with primary brain tumours or brain metastases. We report two cases, aged 2 and 6 months, of MRTK occurring concurrently with a brain tumour. Radical nephrectomy and ventriculo-peritoneal shunting were performed. Both patients expired 2 and 6 months later despite receiving aggressive post-operative chemotherapy and radiotherapy. Conclusion: malignant rhabdoid tumour of the kidney is an uncommon neoplasm of early childhood with a poor prognosis. Due to its significant association with brain tumours or early brain metastases, concurrent brain computer tomographic examination is essential for all patients with this disease.

Original languageEnglish
Pages (from-to)340-342
Number of pages3
JournalEuropean Journal of Pediatrics
Issue number6
Publication statusPublished - 2002
Externally publishedYes



  • Brain tumour
  • Hydrocephalus
  • Rhabdoid tumour of the kidney

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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