Malignant pleural effusion treatment outcomes

Pleurodesis via video-assisted thoracic surgery (VATS) versus tube thoracostomy

Shing Ping Luh, C. Y. Chen, C. Y. Tzao

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Study Objectives: Video-assisted thoracic surgery (VATS) has been widely used in the diagnosis and management of various thoracic diseases. The objective of this retrospective study was to compare the effectiveness of patients undergoing pleurodesis through VATS versus tube thoracostomy for malignant pleural effusion (MPE). Study design was a retrospective review of patients treated in medical centers and hospitals in Taiwan. Patients: One hundred and forty-eight patients with MPE resistant to systemic therapy resulting from various types of carcinomas were retrospectively reviewed. VATS pleurodesis was carried out in 82 and tube thoracostomy with pleurodesis in 66 patients. Results: There were no intraoperative deaths and 4 (2.7%) in-hospital deaths. One hundred and eighteen (79.7%) patients were available for follow-up. There were no statistically significant differences in the preoperative characteristics of the two treatment groups, except that the amount of effusion and the percentage of patients with dyspnea were both higher in the VATS treatment group. The duration of chest tube drainage was significantly longer (p <0.01) in the tube thoracostomy treatment group (9.1 ± 3.3 vs. 6.2 ± 2.3 days). There were no significant differences between the treatment groups with regard to the incidence of surgical complications and perioperative mortality. Median survival was similar in both treatment groups; however, the VATS treatment group had a significantly longer median recurrence-free survival than the tube thoracostomy treatment group. Conclusions: VATS treatment for MPE appears to be superior to tube thoracostomy for diagnostic accuracy and effectiveness in preventing effusion recurrence; however, the role of these treatments for MPE is palliative, and does not significantly prolong survival time.

Original languageEnglish
Pages (from-to)332-336
Number of pages5
JournalThoracic and Cardiovascular Surgeon
Volume54
Issue number5
DOIs
Publication statusPublished - Aug 2006
Externally publishedYes

Fingerprint

Thoracostomy
Pleurodesis
Malignant Pleural Effusion
Video-Assisted Thoracic Surgery
Therapeutics
Survival
Thoracic Diseases
Recurrence
Chest Tubes
Taiwan
Dyspnea
Drainage
Retrospective Studies

Keywords

  • Heart and lung transplantation
  • Heart disease
  • Thoracic surgery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Malignant pleural effusion treatment outcomes : Pleurodesis via video-assisted thoracic surgery (VATS) versus tube thoracostomy. / Luh, Shing Ping; Chen, C. Y.; Tzao, C. Y.

In: Thoracic and Cardiovascular Surgeon, Vol. 54, No. 5, 08.2006, p. 332-336.

Research output: Contribution to journalArticle

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