Maintaining gait performance by cortical activation during dual-task interference: A functional near-infrared spectroscopy study

Chia-Feng Lu, Yan-ci Liu, Yea-Ru Yang, Yu Te Wu, Ray-Yau Wang

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

In daily life, mobility requires walking while performing a cognitive or upper-extremity motor task. Although previous studies have evaluated the effects of dual tasks on gait performance, few studies have evaluated cortical activation and its association with gait disturbance during dual tasks. In this study, we simultaneously assessed gait performance and cerebral oxygenation in the bilateral prefrontal cortices (PFC), premotor cortices (PMC), and supplemental motor areas (SMA), using functional near-infrared spectroscopy, in 17 young adults performing dual tasks. Each participant was evaluated while performing normal- pace walking (NW), walking while performing a cognitive task (WCT), and walking while performing a motor task (WMT). Our results indicated that the left PFC exhibited the strongest and most sustained activation during WCT, and that NW andWMT were associated with minor increases in oxygenation levels during their initial phases. We observed increased activation in channels in the SMA and PMC during WCT and WMT. Gait data indicated that WCT and WMT both caused reductions in walking speed, but these reductions resulted from differing alterations in gait properties. WCT was associated with significant changes in cadence, stride time, and stride length, whereas WMT was associated with reductions in stride length only. During dual-task activities, increased activation of the PMC and SMA correlated with declines in gait performance, indicating a control mechanism for maintaining gait performance during dual tasks. Thus, the regulatory effects of cortical activation on gait behavior enable a second task to be performed while walking. © 2015 Lu et al.
Original languageEnglish
JournalPLoS One
Volume10
Issue number6
DOIs
Publication statusPublished - 2015

Fingerprint

Near infrared spectroscopy
Near-Infrared Spectroscopy
near-infrared spectroscopy
gait
Gait
Motor Cortex
walking
Chemical activation
Oxygenation
Walking
cortex
Prefrontal Cortex
Association reactions
young adults
Upper Extremity
Young Adult

Keywords

  • adult
  • Article
  • cognition
  • controlled study
  • dual-task performance (test)
  • female
  • functional near infrared spectroscopy
  • gait
  • human
  • human experiment
  • male
  • near infrared imaging system
  • near infrared spectroscopy
  • normal human
  • oxygenation
  • prefrontal cortex
  • premotor cortex
  • psychomotor performance
  • supplementary motor area
  • walking speed
  • young adult

Cite this

Maintaining gait performance by cortical activation during dual-task interference: A functional near-infrared spectroscopy study. / Lu, Chia-Feng; Liu, Yan-ci; Yang, Yea-Ru; Wu, Yu Te; Wang, Ray-Yau.

In: PLoS One, Vol. 10, No. 6, 2015.

Research output: Contribution to journalArticle

Lu, Chia-Feng ; Liu, Yan-ci ; Yang, Yea-Ru ; Wu, Yu Te ; Wang, Ray-Yau. / Maintaining gait performance by cortical activation during dual-task interference: A functional near-infrared spectroscopy study. In: PLoS One. 2015 ; Vol. 10, No. 6.
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title = "Maintaining gait performance by cortical activation during dual-task interference: A functional near-infrared spectroscopy study",
abstract = "In daily life, mobility requires walking while performing a cognitive or upper-extremity motor task. Although previous studies have evaluated the effects of dual tasks on gait performance, few studies have evaluated cortical activation and its association with gait disturbance during dual tasks. In this study, we simultaneously assessed gait performance and cerebral oxygenation in the bilateral prefrontal cortices (PFC), premotor cortices (PMC), and supplemental motor areas (SMA), using functional near-infrared spectroscopy, in 17 young adults performing dual tasks. Each participant was evaluated while performing normal- pace walking (NW), walking while performing a cognitive task (WCT), and walking while performing a motor task (WMT). Our results indicated that the left PFC exhibited the strongest and most sustained activation during WCT, and that NW andWMT were associated with minor increases in oxygenation levels during their initial phases. We observed increased activation in channels in the SMA and PMC during WCT and WMT. Gait data indicated that WCT and WMT both caused reductions in walking speed, but these reductions resulted from differing alterations in gait properties. WCT was associated with significant changes in cadence, stride time, and stride length, whereas WMT was associated with reductions in stride length only. During dual-task activities, increased activation of the PMC and SMA correlated with declines in gait performance, indicating a control mechanism for maintaining gait performance during dual tasks. Thus, the regulatory effects of cortical activation on gait behavior enable a second task to be performed while walking. {\circledC} 2015 Lu et al.",
keywords = "adult, Article, cognition, controlled study, dual-task performance (test), female, functional near infrared spectroscopy, gait, human, human experiment, male, near infrared imaging system, near infrared spectroscopy, normal human, oxygenation, prefrontal cortex, premotor cortex, psychomotor performance, supplementary motor area, walking speed, young adult",
author = "Chia-Feng Lu and Yan-ci Liu and Yea-Ru Yang and Wu, {Yu Te} and Ray-Yau Wang",
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year = "2015",
doi = "10.1371/journal.pone.0129390",
language = "English",
volume = "10",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "6",

}

TY - JOUR

T1 - Maintaining gait performance by cortical activation during dual-task interference: A functional near-infrared spectroscopy study

AU - Lu, Chia-Feng

AU - Liu, Yan-ci

AU - Yang, Yea-Ru

AU - Wu, Yu Te

AU - Wang, Ray-Yau

N1 - Export Date: 31 March 2016 CODEN: POLNC 商標: NIRSport 參考文獻: Sparrow, W.A., Bradshaw, E.J., Lamoureux, E., Tirosh, O., Ageing effects on the attention demands of walking (2002) Human Movement Science, 21 (5-6), pp. 961-972. , http://dx.doi.org/10.1016/S0167-9457(0200154-9, PMID: 12620719; Yogev-Seligmann, G., Hausdorff, J.M., Giladi, N., The role of executive function and attention in gait (2008) Movement Disorders, 23 (3), pp. 329-342. , PMID: 18058946; Coppin, A.K., Shumway-Cook, A., Saczynski, J.S., Patel, K.V., Ble, A., Ferrucci, L., Association of executive function and performance of dual-task physical tests among older adults: Analyses from the inchianti study (2006) Age and Ageing, 35 (6), pp. 619-624. , PMID: 17047008; Holtzer, R., Mahoney, J.R., Izzetoglu, M., Izzetoglu, K., Onaral, B., Verghese j. 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PY - 2015

Y1 - 2015

N2 - In daily life, mobility requires walking while performing a cognitive or upper-extremity motor task. Although previous studies have evaluated the effects of dual tasks on gait performance, few studies have evaluated cortical activation and its association with gait disturbance during dual tasks. In this study, we simultaneously assessed gait performance and cerebral oxygenation in the bilateral prefrontal cortices (PFC), premotor cortices (PMC), and supplemental motor areas (SMA), using functional near-infrared spectroscopy, in 17 young adults performing dual tasks. Each participant was evaluated while performing normal- pace walking (NW), walking while performing a cognitive task (WCT), and walking while performing a motor task (WMT). Our results indicated that the left PFC exhibited the strongest and most sustained activation during WCT, and that NW andWMT were associated with minor increases in oxygenation levels during their initial phases. We observed increased activation in channels in the SMA and PMC during WCT and WMT. Gait data indicated that WCT and WMT both caused reductions in walking speed, but these reductions resulted from differing alterations in gait properties. WCT was associated with significant changes in cadence, stride time, and stride length, whereas WMT was associated with reductions in stride length only. During dual-task activities, increased activation of the PMC and SMA correlated with declines in gait performance, indicating a control mechanism for maintaining gait performance during dual tasks. Thus, the regulatory effects of cortical activation on gait behavior enable a second task to be performed while walking. © 2015 Lu et al.

AB - In daily life, mobility requires walking while performing a cognitive or upper-extremity motor task. Although previous studies have evaluated the effects of dual tasks on gait performance, few studies have evaluated cortical activation and its association with gait disturbance during dual tasks. In this study, we simultaneously assessed gait performance and cerebral oxygenation in the bilateral prefrontal cortices (PFC), premotor cortices (PMC), and supplemental motor areas (SMA), using functional near-infrared spectroscopy, in 17 young adults performing dual tasks. Each participant was evaluated while performing normal- pace walking (NW), walking while performing a cognitive task (WCT), and walking while performing a motor task (WMT). Our results indicated that the left PFC exhibited the strongest and most sustained activation during WCT, and that NW andWMT were associated with minor increases in oxygenation levels during their initial phases. We observed increased activation in channels in the SMA and PMC during WCT and WMT. Gait data indicated that WCT and WMT both caused reductions in walking speed, but these reductions resulted from differing alterations in gait properties. WCT was associated with significant changes in cadence, stride time, and stride length, whereas WMT was associated with reductions in stride length only. During dual-task activities, increased activation of the PMC and SMA correlated with declines in gait performance, indicating a control mechanism for maintaining gait performance during dual tasks. Thus, the regulatory effects of cortical activation on gait behavior enable a second task to be performed while walking. © 2015 Lu et al.

KW - adult

KW - Article

KW - cognition

KW - controlled study

KW - dual-task performance (test)

KW - female

KW - functional near infrared spectroscopy

KW - gait

KW - human

KW - human experiment

KW - male

KW - near infrared imaging system

KW - near infrared spectroscopy

KW - normal human

KW - oxygenation

KW - prefrontal cortex

KW - premotor cortex

KW - psychomotor performance

KW - supplementary motor area

KW - walking speed

KW - young adult

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84937834005&partnerID=40&md5=132cdb7707b7957f2e8da11401c6a255

UR - https://www.scopus.com/results/citedbyresults.uri?sort=plf-f&cite=2-s2.0-84937834005&src=s&imp=t&sid=a0ce74a9d57321e60bb359ef9f0b6782&sot=cite&sdt=a&sl=0&origin=recordpage&editSaveSearch=&txGid=1a220fae815107e5ed9e1b5a1e18dfe8

U2 - 10.1371/journal.pone.0129390

DO - 10.1371/journal.pone.0129390

M3 - Article

VL - 10

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 6

ER -