Magnetoencephalography and its usefulness in epilepsy surgery

Yung Yang Lin, Hsiang Yu Yu, Jen Chuen Hsieh, Tzu Chen Yeh, Kai Ping Chang, Chun Hing Yiu, Shang Yeong Kwan, Der Jen Yen, Yang Hsih Shih, Tai-Tong Wong

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

About 10% to 20% of all epileptic patients ultimately suffer from medically intractable epileptic seizures. Epilepsy surgery has been considered as a useful treatment option for these patients. A successful outcome from surgery is a seizure-free state without imposition of neurological deficit. Thus, the goals of presurgical workup include the delineation of the epileptogenic zone and the identification of the nearby brain area with eloquent function. Noninvasive evaluation consists of intensive video-EEG monitoring, magnetic resonance imaging, single photon emission tomography, positron emission tomography, magnetic resonance spectroscopy, and neuropsychological test. For those patients with no convergent localization information, invasive EEG recordings with subdural or depth electrodes are indicated. However, these procedures carry significant risk. Magnetoencephalography (MEG) is a totally noninvasive tool to measure the cerebral magnetic fields generated by intraneuronal currents. The advent of whole-scalp MEG systems facilitates simultaneous measurement of the entire brain activities. MEG has been used to localize the irritative focus and surrounding brain areas with eloquent function, such as sensorimotor cortex. Thus, MEG offers a noninvasive evaluation to help the planning of invasive recordings and surgical treatment. In this article, we will review the basics of MEG and then discuss its applications in the evaluation for epilepsy surgery. Illustrated figures were obtained in our own patients measured with a whole-scalp neuromagnetometer (Vectorview™, 4-D Neuroimaging).

Original languageEnglish
Pages (from-to)273-279
Number of pages7
JournalChinese Journal of Radiology
Volume27
Issue number6
Publication statusPublished - Dec 1 2002
Externally publishedYes

Fingerprint

Magnetoencephalography
Epilepsy
Scalp
Electroencephalography
Brain
Neuropsychological Tests
Magnetic Fields
Photons
Neuroimaging
Positron-Emission Tomography
Electrodes
Seizures
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Therapeutics

Keywords

  • Epilepsy surgery
  • Localization
  • Magnetoencephalography
  • Spike

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Lin, Y. Y., Yu, H. Y., Hsieh, J. C., Yeh, T. C., Chang, K. P., Yiu, C. H., ... Wong, T-T. (2002). Magnetoencephalography and its usefulness in epilepsy surgery. Chinese Journal of Radiology, 27(6), 273-279.

Magnetoencephalography and its usefulness in epilepsy surgery. / Lin, Yung Yang; Yu, Hsiang Yu; Hsieh, Jen Chuen; Yeh, Tzu Chen; Chang, Kai Ping; Yiu, Chun Hing; Kwan, Shang Yeong; Yen, Der Jen; Shih, Yang Hsih; Wong, Tai-Tong.

In: Chinese Journal of Radiology, Vol. 27, No. 6, 01.12.2002, p. 273-279.

Research output: Contribution to journalArticle

Lin, YY, Yu, HY, Hsieh, JC, Yeh, TC, Chang, KP, Yiu, CH, Kwan, SY, Yen, DJ, Shih, YH & Wong, T-T 2002, 'Magnetoencephalography and its usefulness in epilepsy surgery', Chinese Journal of Radiology, vol. 27, no. 6, pp. 273-279.
Lin YY, Yu HY, Hsieh JC, Yeh TC, Chang KP, Yiu CH et al. Magnetoencephalography and its usefulness in epilepsy surgery. Chinese Journal of Radiology. 2002 Dec 1;27(6):273-279.
Lin, Yung Yang ; Yu, Hsiang Yu ; Hsieh, Jen Chuen ; Yeh, Tzu Chen ; Chang, Kai Ping ; Yiu, Chun Hing ; Kwan, Shang Yeong ; Yen, Der Jen ; Shih, Yang Hsih ; Wong, Tai-Tong. / Magnetoencephalography and its usefulness in epilepsy surgery. In: Chinese Journal of Radiology. 2002 ; Vol. 27, No. 6. pp. 273-279.
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