Lymph node metastasis as a single predictor in patients with Borrmann type I gastric cancer

Jen Hao Chen, Chew Wun Wu, Su Shun Lo, Anna F.Y. Li, Mao-Chih Hsieh, King Han Shen, Wing Yiu Lui

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background/Aims: Borrmann type I gastric cancers are rare. Its clinicopathological features have never been reported. Methodology: A total of 33 patients with Borrmann type I gastric cancer was evaluated. 570 patients with Borrmann type II, III and IV were used as references. Results: Borrmann type I gastric cancer occurred preferably in upper stomach, and had more T1 and T2 cancer invasion and early TNM stages, but less lymph node metastasis. Histologically, it had more intestinal type and less scirrhous stromal reaction. Five-year disease-free and overall survival rates in patients with Borrmann type I tumors were significantly higher than that of other types (73.3% vs. 45.8%; P=0.02, and 72.6% vs. 47.8%; P=0.01, respectively). Analysis of the relation between clinicopathological factors and survival showed that only lymph node metastasis significantly affected on disease-free survival with a relative risk of 8.4. Lymph node metastasis also affected overall survival rate at a marginal level (p=0.05). Conclusions: Borrmann type I gastric cancer has higher survival rate. Lymph node metastasis is a single prognostic indicator for survival.

Original languageEnglish
Pages (from-to)981-984
Number of pages4
JournalHepato-Gastroenterology
Volume54
Issue number75
Publication statusPublished - Apr 1 2007
Externally publishedYes

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Stomach Neoplasms
Lymph Nodes
Neoplasm Metastasis
Survival Rate
Disease-Free Survival
Survival
Neoplasms
Stomach

Keywords

  • Advanced gastric cancer
  • Borrmann type I
  • Gastrectomy
  • Lymph node metastasis

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Chen, J. H., Wu, C. W., Lo, S. S., Li, A. F. Y., Hsieh, M-C., Shen, K. H., & Lui, W. Y. (2007). Lymph node metastasis as a single predictor in patients with Borrmann type I gastric cancer. Hepato-Gastroenterology, 54(75), 981-984.

Lymph node metastasis as a single predictor in patients with Borrmann type I gastric cancer. / Chen, Jen Hao; Wu, Chew Wun; Lo, Su Shun; Li, Anna F.Y.; Hsieh, Mao-Chih; Shen, King Han; Lui, Wing Yiu.

In: Hepato-Gastroenterology, Vol. 54, No. 75, 01.04.2007, p. 981-984.

Research output: Contribution to journalArticle

Chen, JH, Wu, CW, Lo, SS, Li, AFY, Hsieh, M-C, Shen, KH & Lui, WY 2007, 'Lymph node metastasis as a single predictor in patients with Borrmann type I gastric cancer', Hepato-Gastroenterology, vol. 54, no. 75, pp. 981-984.
Chen, Jen Hao ; Wu, Chew Wun ; Lo, Su Shun ; Li, Anna F.Y. ; Hsieh, Mao-Chih ; Shen, King Han ; Lui, Wing Yiu. / Lymph node metastasis as a single predictor in patients with Borrmann type I gastric cancer. In: Hepato-Gastroenterology. 2007 ; Vol. 54, No. 75. pp. 981-984.
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