Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells

Yuh Ming Hwu, Sheng Hsiang Li, Robert Kuo kuang Lee, Ming Huei Lin, Yu Hui Tsai, Tian-Shun Tsai

Research output: Contribution to journalArticle

7 Citations (Scopus)


We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.

Original languageEnglish
Pages (from-to)2065-2068
Number of pages4
JournalFertility and Sterility
Issue number6
Publication statusPublished - Dec 2009


ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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