Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells

Yuh Ming Hwu, Sheng Hsiang Li, Robert Kuo kuang Lee, Ming Huei Lin, Yu Hui Tsai, Tian-Shun Tsai

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.

Original languageEnglish
Pages (from-to)2065-2068
Number of pages4
JournalFertility and Sterility
Volume92
Issue number6
DOIs
Publication statusPublished - Dec 2009

Fingerprint

Luteal Cells
Platelet-Derived Growth Factor
Luteinizing Hormone
Gene Expression
Proto-Oncogene Proteins c-sis
Messenger RNA
Genes

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells. / Hwu, Yuh Ming; Li, Sheng Hsiang; Lee, Robert Kuo kuang; Lin, Ming Huei; Tsai, Yu Hui; Tsai, Tian-Shun.

In: Fertility and Sterility, Vol. 92, No. 6, 12.2009, p. 2065-2068.

Research output: Contribution to journalArticle

Hwu, Yuh Ming ; Li, Sheng Hsiang ; Lee, Robert Kuo kuang ; Lin, Ming Huei ; Tsai, Yu Hui ; Tsai, Tian-Shun. / Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells. In: Fertility and Sterility. 2009 ; Vol. 92, No. 6. pp. 2065-2068.
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