Low anxiety disorder comorbidity rate in bipolar disorders in Han Chinese in Taiwan

Yun Hsuan Chang, Shiou Lan Chen, Shih Heng Chen, Chun Hsieh Chu, Sheng Yu Lee, Hsin Fen Yang, Nian Sheng Tzeng, I. Hui Lee, Po See Chen, Tzung Lieh Yeh, San Yuan Huang, Kuei Ru Chou, Yen Kuang Yang, Hui Chen Ko, Ru Band Lu, Jules Angst

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objectives: Studies report high comorbidity of lifetime anxiety disorders with bipolar disorders in Western patients, but it is unclear in Taiwan. The authors explored the comorbidity of anxiety disorders in different bipolar disorder subtypes in Han Chinese in Taiwan. Methods: Three hundred twenty-five patients with bipolar disorder (bipolar I: 120; bipolar II: 205) disorder were recruited from two general medical outpatient services. They were evaluated and their diagnoses confirmed by a psychiatrist using the Chinese version of the Modified Schedule of Affective Disorder and Schizophrenia-Lifetime. The exclusion criteria were: any DSM-IV-TR Axis I diagnosis, other than bipolar disorder, being outside the 18-65-year-old age range, any other major and minor mental illnesses except anxiety disorder, any neurological disorders or organic mental disorders. Results: Thirty-two (26.7%) of patients were comorbid with lifetime anxiety disorder and bipolar I, 80 (39.0%) with lifetime anxiety disorder and bipolar II, 7 (5.8%) were comorbid with two or more anxiety disorders and bipolar I, and 27 (13.2%) with two or more anxiety disorders and bipolar II. Conclusion: That more than twice as many bipolar II than bipolar I patients reported two or more anxiety disorders implies that the complication is more prevalent in bipolar II patients.

Original languageEnglish
Pages (from-to)194-197
Number of pages4
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Volume36
Issue number1
DOIs
Publication statusPublished - Jan 10 2012

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Keywords

  • Anxiety disorder
  • Bipolar disorder
  • Comorbidity
  • Han Chinese

ASJC Scopus subject areas

  • Biological Psychiatry
  • Pharmacology

Cite this

Chang, Y. H., Chen, S. L., Chen, S. H., Chu, C. H., Lee, S. Y., Yang, H. F., Tzeng, N. S., Lee, I. H., Chen, P. S., Yeh, T. L., Huang, S. Y., Chou, K. R., Yang, Y. K., Ko, H. C., Lu, R. B., & Angst, J. (2012). Low anxiety disorder comorbidity rate in bipolar disorders in Han Chinese in Taiwan. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 36(1), 194-197. https://doi.org/10.1016/j.pnpbp.2011.09.013