Low ambient temperature as the only meteorological risk factor of seizure occurrence: A multivariate study

Kai Chieh Chang, Tzy Haw Wu, Jean Ching Yuan Fann, Sam Li sheng Chen, Amy Ming Fang Yen, Sherry Yueh Hsia Chiu, Fei Chi Liu, Hsiu Hsi Chen, Horng Huei Liou

Research output: Contribution to journalArticle

Abstract

Background: The onset of epileptic seizures is influenced by weather, which is multifactorial. It is unknown which specific weather factors affect the occurrence of seizures. Objectives: We studied the correlation between the onset of epileptic seizures and multiple weather parameters based on a population-based registry profile. Methods: We determined the number of patients who visited emergency services in Taiwan diagnosed as having epilepsy. Then we used a linear regression model to analyze the monthly average number of patients who received emergency treatment for epilepsy in relation to temperature, barometric pressure, accumulated precipitation, relative humidity, and hours of sunshine. The Poisson regression model was used to analyze multiple meteorological factors in relation to the number of daily emergency visits because of epilepsy. A receiver operating characteristic curve was used to determine the cutoff temperature for the occurrence of seizures. Results: Temperature appeared to be the robust factor for the onset of epilepsy. For every 1 °C decrease in temperature, there was a relative risk increase of 1.016 in the number of emergency visits as a result of epilepsy. Temperature lower than 18 °C had the best predictive value for seizure. Barometric pressure, accumulated precipitation, relative humidity, and the number of hours of sunshine were not related to the occurrence of seizures. Significance: Our results suggest that temperature is the only influential meteorological factor that affects seizure occurrence.

Original languageEnglish
Article number106283
JournalEpilepsy and Behavior
Volume100
DOIs
Publication statusPublished - Nov 1 2019

Fingerprint

Meteorological Concepts
Epilepsy
Seizures
Temperature
Weather
Emergencies
Sunlight
Humidity
Linear Models
Pressure
Emergency Treatment
Taiwan
ROC Curve
Registries

Keywords

  • Epilepsy
  • Meteorology
  • Seizure
  • Temperature

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

Cite this

Low ambient temperature as the only meteorological risk factor of seizure occurrence : A multivariate study. / Chang, Kai Chieh; Wu, Tzy Haw; Fann, Jean Ching Yuan; Chen, Sam Li sheng; Yen, Amy Ming Fang; Chiu, Sherry Yueh Hsia; Liu, Fei Chi; Chen, Hsiu Hsi; Liou, Horng Huei.

In: Epilepsy and Behavior, Vol. 100, 106283, 01.11.2019.

Research output: Contribution to journalArticle

Chang, Kai Chieh ; Wu, Tzy Haw ; Fann, Jean Ching Yuan ; Chen, Sam Li sheng ; Yen, Amy Ming Fang ; Chiu, Sherry Yueh Hsia ; Liu, Fei Chi ; Chen, Hsiu Hsi ; Liou, Horng Huei. / Low ambient temperature as the only meteorological risk factor of seizure occurrence : A multivariate study. In: Epilepsy and Behavior. 2019 ; Vol. 100.
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