Love hurts

An fMRI study

Yawei Cheng, Chenyi Chen, Ching Po Lin, Kun Hsien Chou, Jean Decety

Research output: Contribution to journalArticle

118 Citations (Scopus)

Abstract

Being in a close relationship is essential to human existence. Such closeness can be described as including other in the self and be underpinned on social attachment system, which evolved from a redirection of nociceptive mechanisms. To what extent does imagining a loved-one differs from imagining an unfamiliar individual being in painful situations? In this functional MRI study, participants were exposed to animated stimuli depicting hands or feet in painful and non-painful situations, and instructed to imagine these scenarios from three different perspectives: self, loved-one and stranger after being primed with their respective photographs. In line with previous studies, the three perspectives were associated with activation of the neural network involved in pain processing. Specifically, adopting the perspective of a loved-one increased activity in the anterior cingulate cortex and insula, whereas imagining a stranger induced a signal increase in the right temporo-parietal junction (TPJ) and superior frontal gyrus. The closer the participants' relationships were with their partner, the greater the deactivation in the right TPJ. A negative effective connectivity between the right TPJ and the insula, and a positive one with the superior frontal gyrus were found when participants imagined the perspective of a stranger. These results demonstrate that intimacy affects the bottom-up information processing involved in empathy, as indicated by greater overlap between neural representations of the self and the other.

Original languageEnglish
Pages (from-to)923-929
Number of pages7
JournalNeuroImage
Volume51
Issue number2
DOIs
Publication statusPublished - Jun 2010
Externally publishedYes

Fingerprint

Ego
Love
Prefrontal Cortex
Magnetic Resonance Imaging
Gyrus Cinguli
Automatic Data Processing
Foot
Hand
Pain

Keywords

  • Anterior cingulate cortex
  • Attachment
  • Empathy
  • Insula
  • Intimacy
  • Perspective taking
  • Temporo-parietal junction

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

Cite this

Cheng, Y., Chen, C., Lin, C. P., Chou, K. H., & Decety, J. (2010). Love hurts: An fMRI study. NeuroImage, 51(2), 923-929. https://doi.org/10.1016/j.neuroimage.2010.02.047

Love hurts : An fMRI study. / Cheng, Yawei; Chen, Chenyi; Lin, Ching Po; Chou, Kun Hsien; Decety, Jean.

In: NeuroImage, Vol. 51, No. 2, 06.2010, p. 923-929.

Research output: Contribution to journalArticle

Cheng, Y, Chen, C, Lin, CP, Chou, KH & Decety, J 2010, 'Love hurts: An fMRI study', NeuroImage, vol. 51, no. 2, pp. 923-929. https://doi.org/10.1016/j.neuroimage.2010.02.047
Cheng Y, Chen C, Lin CP, Chou KH, Decety J. Love hurts: An fMRI study. NeuroImage. 2010 Jun;51(2):923-929. https://doi.org/10.1016/j.neuroimage.2010.02.047
Cheng, Yawei ; Chen, Chenyi ; Lin, Ching Po ; Chou, Kun Hsien ; Decety, Jean. / Love hurts : An fMRI study. In: NeuroImage. 2010 ; Vol. 51, No. 2. pp. 923-929.
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