Long-term results of esophageal transection and devascularization procedure in treatment of esophageal variceal bleeding.

M. T. Huang, P. H. Lee, C. S. Lee

Research output: Contribution to journalArticle

Abstract

Fifty-three patients with bleeding esophageal varices received a non-shunting operation--esophageal transection and devascularization of the proximal stomach with splenectomy--from March 1977 to October 1986. The ages of these patients ranged from 26 to 69 years with a mean of 49.70 +/- 10.03 years (+/- SD). Thirty-six patients were male and 17 were female. The pathology of the liver was post-necrotic liver cirrhosis in 39 cases, alcoholic liver cirrhosis in seven cases, liver cirrhosis with hepatocellular carcinoma in six cases and non-cirrhotic in one case. The operative mortality was 26.4% (14/53); major causes of operative death were due to liver failure (six cases) and recurrent bleeding (five cases). The operative mortality was 10% in Child's Class A, 37.5% in Class B, and 73% in Class C (p <0.05 by Fisher's exact test). The operative mortality was 18.5% in the elective group and 40% in the emergent group, but the difference was not statistically significant. The absolute overall five-year survival rate was 61.1%, but the expected 10-year survival was only 46.4%. The major causes of death during long-term follow-up were liver failure (nine cases) and recurrent bleeding (seven cases). The incidence of recurrent bleeding of esophageal varices was 44.4% in long-term follow-up. Two patients developed hepatocellular carcinoma 22 and 37 months after their operations; this incidence was much lower than that of our previous report.(ABSTRACT TRUNCATED AT 250 WORDS)

Original languageEnglish
Pages (from-to)117-121
Number of pages5
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume92
Issue number2
Publication statusPublished - Feb 1993
Externally publishedYes

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Hemorrhage
Esophageal and Gastric Varices
Liver Failure
Liver Cirrhosis
Mortality
Cause of Death
Hepatocellular Carcinoma
Alcoholic Liver Cirrhosis
Incidence
Splenectomy
Therapeutics
Stomach
Survival Rate
Pathology
Survival
Liver

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Long-term results of esophageal transection and devascularization procedure in treatment of esophageal variceal bleeding.",
abstract = "Fifty-three patients with bleeding esophageal varices received a non-shunting operation--esophageal transection and devascularization of the proximal stomach with splenectomy--from March 1977 to October 1986. The ages of these patients ranged from 26 to 69 years with a mean of 49.70 +/- 10.03 years (+/- SD). Thirty-six patients were male and 17 were female. The pathology of the liver was post-necrotic liver cirrhosis in 39 cases, alcoholic liver cirrhosis in seven cases, liver cirrhosis with hepatocellular carcinoma in six cases and non-cirrhotic in one case. The operative mortality was 26.4{\%} (14/53); major causes of operative death were due to liver failure (six cases) and recurrent bleeding (five cases). The operative mortality was 10{\%} in Child's Class A, 37.5{\%} in Class B, and 73{\%} in Class C (p <0.05 by Fisher's exact test). The operative mortality was 18.5{\%} in the elective group and 40{\%} in the emergent group, but the difference was not statistically significant. The absolute overall five-year survival rate was 61.1{\%}, but the expected 10-year survival was only 46.4{\%}. The major causes of death during long-term follow-up were liver failure (nine cases) and recurrent bleeding (seven cases). The incidence of recurrent bleeding of esophageal varices was 44.4{\%} in long-term follow-up. Two patients developed hepatocellular carcinoma 22 and 37 months after their operations; this incidence was much lower than that of our previous report.(ABSTRACT TRUNCATED AT 250 WORDS)",
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AU - Lee, P. H.

AU - Lee, C. S.

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N2 - Fifty-three patients with bleeding esophageal varices received a non-shunting operation--esophageal transection and devascularization of the proximal stomach with splenectomy--from March 1977 to October 1986. The ages of these patients ranged from 26 to 69 years with a mean of 49.70 +/- 10.03 years (+/- SD). Thirty-six patients were male and 17 were female. The pathology of the liver was post-necrotic liver cirrhosis in 39 cases, alcoholic liver cirrhosis in seven cases, liver cirrhosis with hepatocellular carcinoma in six cases and non-cirrhotic in one case. The operative mortality was 26.4% (14/53); major causes of operative death were due to liver failure (six cases) and recurrent bleeding (five cases). The operative mortality was 10% in Child's Class A, 37.5% in Class B, and 73% in Class C (p <0.05 by Fisher's exact test). The operative mortality was 18.5% in the elective group and 40% in the emergent group, but the difference was not statistically significant. The absolute overall five-year survival rate was 61.1%, but the expected 10-year survival was only 46.4%. The major causes of death during long-term follow-up were liver failure (nine cases) and recurrent bleeding (seven cases). The incidence of recurrent bleeding of esophageal varices was 44.4% in long-term follow-up. Two patients developed hepatocellular carcinoma 22 and 37 months after their operations; this incidence was much lower than that of our previous report.(ABSTRACT TRUNCATED AT 250 WORDS)

AB - Fifty-three patients with bleeding esophageal varices received a non-shunting operation--esophageal transection and devascularization of the proximal stomach with splenectomy--from March 1977 to October 1986. The ages of these patients ranged from 26 to 69 years with a mean of 49.70 +/- 10.03 years (+/- SD). Thirty-six patients were male and 17 were female. The pathology of the liver was post-necrotic liver cirrhosis in 39 cases, alcoholic liver cirrhosis in seven cases, liver cirrhosis with hepatocellular carcinoma in six cases and non-cirrhotic in one case. The operative mortality was 26.4% (14/53); major causes of operative death were due to liver failure (six cases) and recurrent bleeding (five cases). The operative mortality was 10% in Child's Class A, 37.5% in Class B, and 73% in Class C (p <0.05 by Fisher's exact test). The operative mortality was 18.5% in the elective group and 40% in the emergent group, but the difference was not statistically significant. The absolute overall five-year survival rate was 61.1%, but the expected 10-year survival was only 46.4%. The major causes of death during long-term follow-up were liver failure (nine cases) and recurrent bleeding (seven cases). The incidence of recurrent bleeding of esophageal varices was 44.4% in long-term follow-up. Two patients developed hepatocellular carcinoma 22 and 37 months after their operations; this incidence was much lower than that of our previous report.(ABSTRACT TRUNCATED AT 250 WORDS)

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