Long-term mortality assessment using biological measures among elderly people. Ten-year follow-up of 597 healthy elderly subjects in Taiwan

Tzy Haw Wu, Ti Kai Lee, Ming Fang Yen, Tao Hsin Tung, Tony Hsiu Hsi Chen

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background. Identifying biological measures that are predictive of mortality for elderly people aged over 65 years has not been fully elucidated in oriental studies. Objective. The associations between these biological measures and long-term mortality were therefore investigated, and classifications for risk of death were developed among Taiwanese elderly people Methods. Data used in this study were derived from a total of 597 apparently healthy subjects aged over 65 years identified from a nationwide survey that was conducted between 1989 and 1991 in Taiwan. Each participant received a physical examination and a wide range of biological measures. These 597 apparently healthy subjects were followed to 31 December 1999 to determine the cause of death. The grouping technique using factor analysis was first used to aggregate similar characteristics of biological measures into reduced components. Risk of death for each subject was classified into four groups: good (A), fair (B), modest (C) and poor (D). Hazard ratios for groups B, C, D against A were calculated. Results. The overall 10-year survival rate was 72% [95% confidence interval (CI) 68-76%]. The adjusted hazard ratios for all-cause death in high and mid-level categories of haematological components versus the lowest group were 0.51 (95% CI 0.33-0.80) and 0.56 (95% CI 0.37-0.85), respectively. Group D had a 6-fold risk of death as compared with group A (relative risk = 6.34, 95% CI 3.85-10.52). The corresponding figures were 2.48 (95% CI 1.43-4.29) and 1.60 (95% CI 2.88-6.89) for groups B and C, respectively. Conclusions. The relationships of biological measures to long-term mortality were elucidated. Information on classification for risk of death may be helpful for elderly people to pay attention to their health status after receiving a health check-up.

Original languageEnglish
Pages (from-to)272-277
Number of pages6
JournalFamily Practice
Volume19
Issue number3
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Taiwan
Healthy Volunteers
Confidence Intervals
Mortality
Cause of Death
Health Status
Statistical Factor Analysis
Physical Examination
Survival Rate
Health

Keywords

  • Biological measures
  • Elderly people
  • Long-term mortality

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Long-term mortality assessment using biological measures among elderly people. Ten-year follow-up of 597 healthy elderly subjects in Taiwan. / Wu, Tzy Haw; Lee, Ti Kai; Yen, Ming Fang; Tung, Tao Hsin; Chen, Tony Hsiu Hsi.

In: Family Practice, Vol. 19, No. 3, 2002, p. 272-277.

Research output: Contribution to journalArticle

@article{c2d08e39089c467fb36fe931062cdb67,
title = "Long-term mortality assessment using biological measures among elderly people. Ten-year follow-up of 597 healthy elderly subjects in Taiwan",
abstract = "Background. Identifying biological measures that are predictive of mortality for elderly people aged over 65 years has not been fully elucidated in oriental studies. Objective. The associations between these biological measures and long-term mortality were therefore investigated, and classifications for risk of death were developed among Taiwanese elderly people Methods. Data used in this study were derived from a total of 597 apparently healthy subjects aged over 65 years identified from a nationwide survey that was conducted between 1989 and 1991 in Taiwan. Each participant received a physical examination and a wide range of biological measures. These 597 apparently healthy subjects were followed to 31 December 1999 to determine the cause of death. The grouping technique using factor analysis was first used to aggregate similar characteristics of biological measures into reduced components. Risk of death for each subject was classified into four groups: good (A), fair (B), modest (C) and poor (D). Hazard ratios for groups B, C, D against A were calculated. Results. The overall 10-year survival rate was 72{\%} [95{\%} confidence interval (CI) 68-76{\%}]. The adjusted hazard ratios for all-cause death in high and mid-level categories of haematological components versus the lowest group were 0.51 (95{\%} CI 0.33-0.80) and 0.56 (95{\%} CI 0.37-0.85), respectively. Group D had a 6-fold risk of death as compared with group A (relative risk = 6.34, 95{\%} CI 3.85-10.52). The corresponding figures were 2.48 (95{\%} CI 1.43-4.29) and 1.60 (95{\%} CI 2.88-6.89) for groups B and C, respectively. Conclusions. The relationships of biological measures to long-term mortality were elucidated. Information on classification for risk of death may be helpful for elderly people to pay attention to their health status after receiving a health check-up.",
keywords = "Biological measures, Elderly people, Long-term mortality",
author = "Wu, {Tzy Haw} and Lee, {Ti Kai} and Yen, {Ming Fang} and Tung, {Tao Hsin} and Chen, {Tony Hsiu Hsi}",
year = "2002",
language = "English",
volume = "19",
pages = "272--277",
journal = "Family Practice",
issn = "0263-2136",
publisher = "Oxford University Press",
number = "3",

}

TY - JOUR

T1 - Long-term mortality assessment using biological measures among elderly people. Ten-year follow-up of 597 healthy elderly subjects in Taiwan

AU - Wu, Tzy Haw

AU - Lee, Ti Kai

AU - Yen, Ming Fang

AU - Tung, Tao Hsin

AU - Chen, Tony Hsiu Hsi

PY - 2002

Y1 - 2002

N2 - Background. Identifying biological measures that are predictive of mortality for elderly people aged over 65 years has not been fully elucidated in oriental studies. Objective. The associations between these biological measures and long-term mortality were therefore investigated, and classifications for risk of death were developed among Taiwanese elderly people Methods. Data used in this study were derived from a total of 597 apparently healthy subjects aged over 65 years identified from a nationwide survey that was conducted between 1989 and 1991 in Taiwan. Each participant received a physical examination and a wide range of biological measures. These 597 apparently healthy subjects were followed to 31 December 1999 to determine the cause of death. The grouping technique using factor analysis was first used to aggregate similar characteristics of biological measures into reduced components. Risk of death for each subject was classified into four groups: good (A), fair (B), modest (C) and poor (D). Hazard ratios for groups B, C, D against A were calculated. Results. The overall 10-year survival rate was 72% [95% confidence interval (CI) 68-76%]. The adjusted hazard ratios for all-cause death in high and mid-level categories of haematological components versus the lowest group were 0.51 (95% CI 0.33-0.80) and 0.56 (95% CI 0.37-0.85), respectively. Group D had a 6-fold risk of death as compared with group A (relative risk = 6.34, 95% CI 3.85-10.52). The corresponding figures were 2.48 (95% CI 1.43-4.29) and 1.60 (95% CI 2.88-6.89) for groups B and C, respectively. Conclusions. The relationships of biological measures to long-term mortality were elucidated. Information on classification for risk of death may be helpful for elderly people to pay attention to their health status after receiving a health check-up.

AB - Background. Identifying biological measures that are predictive of mortality for elderly people aged over 65 years has not been fully elucidated in oriental studies. Objective. The associations between these biological measures and long-term mortality were therefore investigated, and classifications for risk of death were developed among Taiwanese elderly people Methods. Data used in this study were derived from a total of 597 apparently healthy subjects aged over 65 years identified from a nationwide survey that was conducted between 1989 and 1991 in Taiwan. Each participant received a physical examination and a wide range of biological measures. These 597 apparently healthy subjects were followed to 31 December 1999 to determine the cause of death. The grouping technique using factor analysis was first used to aggregate similar characteristics of biological measures into reduced components. Risk of death for each subject was classified into four groups: good (A), fair (B), modest (C) and poor (D). Hazard ratios for groups B, C, D against A were calculated. Results. The overall 10-year survival rate was 72% [95% confidence interval (CI) 68-76%]. The adjusted hazard ratios for all-cause death in high and mid-level categories of haematological components versus the lowest group were 0.51 (95% CI 0.33-0.80) and 0.56 (95% CI 0.37-0.85), respectively. Group D had a 6-fold risk of death as compared with group A (relative risk = 6.34, 95% CI 3.85-10.52). The corresponding figures were 2.48 (95% CI 1.43-4.29) and 1.60 (95% CI 2.88-6.89) for groups B and C, respectively. Conclusions. The relationships of biological measures to long-term mortality were elucidated. Information on classification for risk of death may be helpful for elderly people to pay attention to their health status after receiving a health check-up.

KW - Biological measures

KW - Elderly people

KW - Long-term mortality

UR - http://www.scopus.com/inward/record.url?scp=0036265239&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036265239&partnerID=8YFLogxK

M3 - Article

VL - 19

SP - 272

EP - 277

JO - Family Practice

JF - Family Practice

SN - 0263-2136

IS - 3

ER -