Long-term management of craniofacial osteosarcoma

Erh Kang Chou, Sophia Chia Ning Chang, Philip Kuo Ting Chen, Yu Ray Chen, Jack Chung Kai Yu, Shih Ming Jung, Sophia Chia Ning Chang

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Primary osteosarcoma of the calvarium is rare. A 22-year-old female patient was admitted for a progressively enlarging, indurated mass under her scalp for 6 months. A computed tomographic scan revealed a 4 × 3 × 2-cm osteolytic lesion over the right parietal cortex with a sunburst appearance. The patient underwent en bloc tumor resection using bicortical parietal craniectomy with a 2-cm margin of normal bone, including the tightly adherent periosteum over the tumor. Immediate cranioplasty was performed with split-thickness autogenous calvarial bone grafts. Histopathologic examination showed the tumor to be a primary high-grade osteosarcoma of the skull. She received postoperative chemotherapy. She has recovered well and remains without any evidence of disease at her most recent, 8-year follow-up. The key to disease-free survival in treating primary osteosarcoma of the calvarium is complete surgical resection with immediate reconstruction followed by adjuvant chemotherapy.

Original languageEnglish
Pages (from-to)406-409
Number of pages4
JournalJournal of Craniofacial Surgery
Issue number2
Publication statusPublished - Mar 1 2009
Externally publishedYes


  • Calvarial bone graft
  • Craniectomy
  • Osteosarcoma

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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