Long-term indoor air conditioner filtration and cardiovascular health

A randomized crossover intervention study

Hsiao Chi Chuang, Kin Fai Ho, Lian Yu Lin, Ta Yuan Chang, Gui Bing Hong, Chi Ming Ma, I. Jung Liu, Kai Jen Chuang

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The association of short-term air pollution filtration with cardiovascular health has been documented. However, the effect of long-term indoor air conditioner filtration on the association between air pollution and cardiovascular health is still unclear. We recruited 200 homemakers from Taipei and randomly assigned 100 of them to air filtration or control intervention; six home visits were conducted per year from 2013 to 2014. The participants under air filtration intervention during 2013 were reassigned to control intervention in 2014. The air pollution measurements consisted of particulate matter less than or equal to 2.5 μm in diameter (PM2.5) and total volatile organic compounds (VOCs); blood pressure was monitored for each participant during each visit. The following morning, blood samples were collected after air pollution monitoring. The blood samples were used to analyze biological markers, including high sensitivity-C-reactive protein (hs-CRP), 8-hydroxy-2′-deoxyguanosine (8-OHdG) and fibrinogen. Household information, including cleaning, cooking, and air conditioning, was collected by a questionnaire. Mixed-effects models were used to investigate the associations among air pollution measurements, blood pressure and biological markers. The results showed that increased levels of PM2.5 and total VOCs were associated with increased hs-CRP, 8-OHdG and blood pressure. The health variables were higher among participants in the control intervention phase than among those in the air filtration intervention phase. We concluded that air pollution exposure was associated with systemic inflammation, oxidative stress and elevated blood pressure. The long-term filtration of air pollution with an air conditioner filter was associated with cardiovascular health of adults.

Original languageEnglish
Pages (from-to)91-96
Number of pages6
JournalEnvironment International
Volume106
DOIs
Publication statusPublished - Sep 1 2017

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indoor air
atmospheric pollution
blood
air
volatile organic compound
pollution exposure
pollution monitoring
protein
air conditioning
health
particulate matter
filter

Keywords

  • Air pollution
  • Blood pressure
  • Epidemiology
  • Indoor air filtration
  • Inflammation

ASJC Scopus subject areas

  • Environmental Science(all)

Cite this

Long-term indoor air conditioner filtration and cardiovascular health : A randomized crossover intervention study. / Chuang, Hsiao Chi; Ho, Kin Fai; Lin, Lian Yu; Chang, Ta Yuan; Hong, Gui Bing; Ma, Chi Ming; Liu, I. Jung; Chuang, Kai Jen.

In: Environment International, Vol. 106, 01.09.2017, p. 91-96.

Research output: Contribution to journalArticle

Chuang, Hsiao Chi ; Ho, Kin Fai ; Lin, Lian Yu ; Chang, Ta Yuan ; Hong, Gui Bing ; Ma, Chi Ming ; Liu, I. Jung ; Chuang, Kai Jen. / Long-term indoor air conditioner filtration and cardiovascular health : A randomized crossover intervention study. In: Environment International. 2017 ; Vol. 106. pp. 91-96.
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