LOCATION OF DISULFIDE BRIDGES IN CARDIOTOXIN FROM THE VENOM OF FORMOSAN COBRA (NAJA NAJA ATRA)

Kozo Narita, King‐Lan ‐L Cheng, Wen‐Chang ‐C Chang, Tung‐Bin ‐B Lo

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The location of the four disulfide bridges in cardiotoxin from the venom of the Formosan cobra, Naja naja atra, was determined by isolating cystine‐containing peptides from the enzymic and partial acid hydrolyzates of the intact toxin. The results indicate that the disulfide bridges are formed by half cystine residues 3–21, 14–38, 42–53, and 54–59. The amino acid sequence at the position 48–49 was revised to ‐Leu‐Val‐ instead of ‐Val‐Leu‐ as reported previously.

Original languageEnglish
Pages (from-to)229-237
Number of pages9
JournalInternational Journal of Peptide and Protein Research
Volume11
Issue number3
DOIs
Publication statusPublished - Jan 1 1978
Externally publishedYes

Keywords

  • cardiotoxin
  • disulfide bridges
  • Formosan cobra venom
  • Naja naja atra.

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'LOCATION OF DISULFIDE BRIDGES IN CARDIOTOXIN FROM THE VENOM OF FORMOSAN COBRA (NAJA NAJA ATRA)'. Together they form a unique fingerprint.

Cite this